Báo cáo khoa học: "Altered maturation of dendritic cells by taxol, an anticancer drug" ppt

... 229–234 Altered maturation of dendritic cells by taxol, an anticancer drug Hong-Gu Joo Department of Veterinary Medicine, Cheju National University, Jeju 690-756, Korea Taxol is a clinically useful anticancer ... direct killing of DCs. Key words: dendritic cells, taxol, maturation Introduction Taxol is a clinically effective anticancer drug against a variety o...

Ngày tải lên: 07/08/2014, 17:22

... elegans upp-1 mutant interacts with the anticancer drug 5-FU. As C. elegans is a simple metazoan, interpreting the relationships between anticancer drugs and gene function may be less complex than ... worms and three upp-1 mutants. Fig. S3. Sequence alignments of C. elegans UPP-1 and human UPP-1. Fig. S4. Sequence alignments of C29F7.3 and F40F8.1. Fig. S5. Sequence alignments of hu...

Ngày tải lên: 30/03/2014, 01:20

... Iron-induced upregulation of cell surface CD1d is accompanied by an increase in total protein and mRNA transcripts. HepG2 cells were cultured as indicated in legend of Fig. 1 and cells processed for ... comments on TEM, and M. Santos and R. Hultcrantz for critical reading of the manu- script. We also thank M. de Sousa for mentoring this work. M.C. and C.F.P. were supported by...

Ngày tải lên: 19/02/2014, 16:20

... expression in androgen dependant prostate cancer cells (LNCaP). (A) LNCaP cells transfected with either EGFP (left panel) or EGFP-TPD52 (right panel) fusion protein producing recombinant vector and, 24 ... LNCaP cells (Fig. 4G). In 30% of the TPD52 knockdown cells, a significant decrease of Dw m (P £ 0.0013) could be observed, whereas nontransfected or mock transfected cells were...

Ngày tải lên: 30/03/2014, 02:20

Ngày tải lên: 07/08/2014, 18:21

... process of C-peptide and ana- lyzed the formation of oligomers and their secondary structure by complementary methods, including the detection of C-peptide oligomers by PAGE electropho- resis and ... of SDS. In conclusion, we find that the formation of oligo- meric species is accompanied by a structural transition from a largely random coil C-peptide structure to pre- dominantl...

Ngày tải lên: 18/02/2014, 04:20

... mononucleosome size of samples con- sisting of a mixture of hepta-, octa- and nonanucleosomes and half the amount of hexa- and decanucleosomes (6- to 10-mer sample). (A) (a) Nonamer of a sequential ... 2008) doi:10.1111/j.1742-4658.2008.06522.x The folding of eukaryotic DNA into the 30 nm fibre comprises the first level of transcriptionally dormant chromatin. Understanding its str...

Ngày tải lên: 18/02/2014, 18:20

... are an important source of fuel for many tissues because they can yield relatively large quantities of ATP, obesity-related persistent oversupply of nonesterified fatty acids and accumula- tion of ... effects of palmitoyl-CoA was inhibi- tion of the ANT. Assessment of the metabolic control of fluxes and intermediate concentrations by the ANT then revealed that this enzyme pa...

Ngày tải lên: 19/02/2014, 05:20

... and no replacement of any of the two axial ligands of the iron, His18 or RNO, by an amino acid side-chain of the antibody protein. Binding site topology of antibody 3A3 Figure 1 shows the changes ... sulphoxidation of thioanisole catalysed by Table 3. Yield and enantiomeric excess for the S-oxidation of thioani- sole by H 2 O 2 in the presence of microperoxidase 8 (MP8...

Ngày tải lên: 19/02/2014, 12:20

... 0.6 0.7 0.8 0.9 1 10 100 1000 10000 100000 1e+06 size(KB) recall precision 434 Proceedings of the COLING/ACL 2006 Main Conference Poster Sessions, pages 428–435, Sydney, July 2006. c 2006

Ngày tải lên: 20/02/2014, 12:20