Báo cáo khoa học: " Activation of embryonic intermediate filaments contributes to glial scar formation after spinal cord injury in rats" potx

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Ngày tải lên: 07/08/2014, 17:22

... major role in receptor assembly or sur- face expression. In uence of aR55F and aR55W mutant receptors on the binding of acetylcholine The binding properties of ACh were investigated in intact Xenopus ... localized to the a–c and a–d subunit interfaces. We investigated the involvement of amino acids lying at an adjacent interface (c–a) in receptor properties. Recombinant Torpe...

Ngày tải lên: 19/02/2014, 07:20

... transferred in the membrane fraction. Binding properties of muscarinic ligands with M 2 ::GOA-1 fusion protein The binding properties of muscarinic ligands were examined to reveal whether the M 2 receptor ... Sade ´ eW (1994) Activation of a GTP-binding protein and a GTP- binding-protein-coupled receptor kinase (beta-adrener- gic-receptor kinase-1) by a muscarinic receptor m 2 mut...

Ngày tải lên: 07/03/2014, 11:20

... human insulinoma cell line CM. J Endocrinol 161, 59–68. 47 Stadheim TA, Saluta GR & Kucera GL (2000) Role of c-Jun N-terminal kinase ⁄ p38 stress signaling in 1-b-d- arabinofuranosylcytosine-induced ... further indicating that hA-elicited activation of c-Jun and ATF-2 are independent of the ERK pathway. Activation of ATF-2 is associated with increased CRE-DNA binding activit...

Ngày tải lên: 07/03/2014, 12:20

... production of b-casein. Expression of brain type fatty acid binding protein brain type fatty acid binding protein in virgin transgenic mice also resulted in a reduced ratio of n-6 ⁄ n-3 PUFA, a robust increase ... alternation of the n-6 ⁄ n-3 compositional ratio in favor of n-3 fatty acid results in a phosphorylation of Stat5, indicating a potential role of n-3 fatty aci...

Ngày tải lên: 16/03/2014, 10:20

... activator inhibitor; HAI-1KD-1, secreted form of hepatocyte growth factor activator inhibitor type 1 consisting of the first Kunitz domain; HGF ⁄ SF, hepatocyte growth factor ⁄ scatter factor; HGFA, ... activated in response to tissue injury. Although thrombin is considered to be an activator of pro-HGFA, alterna- tive pro-HGFA activation pathways in tumor microenvironments r...

Ngày tải lên: 23/03/2014, 07:20

... western blotting using staining with anti- bodies to total PMCA, PMCA4 isoform and acety- lated tubulin. These proteins were present in PMVs (Fig. 1A, ‘PMV’). After partition in Triton X-114, total ... aliquots were incubated in the presence of increasing concentrations of calmodu- lin, followed by the immediate determination of PMCA activity and the amount of acetylated tub...

Ngày tải lên: 23/03/2014, 07:20

... adsorption of Cel7A after incubation for 120 min as representative results of four time points (120, 180, 240, and 320 min). The lines indicate the fitting of the data to the two-bind- ing-site ... University of Tokyo, Japan Cellulose is a linear polymer of b-1,4-linked anhydrous glucose residues, and is the major component of plant cell walls. In nature, cellulose chains are...

Ngày tải lên: 23/03/2014, 09:21

... blocking of the ATP- ase activating effect of glucose was not the result of a toxic effect of 2-deoxy-d-glucose, as subsequent incuba- tion in the presence of 10 mm glucose resulted again in H + -ATPase ... twice in 2 mL of 0.1 m Tris ⁄ HCl, pH 7.2, containing 5 mm EGTA and 5 mm dithiothreitol, incubated with stirring for 10 min, washed with water (containing 1 mm dithio- th...

Ngày tải lên: 23/03/2014, 11:20

... Studies of the binding of heparin oligosaccharides to well- known heparin-binding proteins, including the protease thrombin and fibroblast growth factor, have reported binding affinities (K D ) in the ... the binding of GAGs to the N-terminal part of the prodomain may accelerate the reaction in the first rate-limiting step in the activation of the zymogen, in which the co...

Ngày tải lên: 30/03/2014, 02:20