Different roles of functional residues in the hydrophobic bi

Báo cáo khoa học: Glutamic acid residues in the C-terminal extension of small heat shock protein 25 are critical for structural and functional integrity pptx

... examined the role of residues in the C-terminal extensions of other sHsps, notably aA- and aB-crystallin, the ﬂexible regions of these proteins are unique and distinct from that of Hsp25. The ... residues in the C-terminal extension of small heat shock protein 25 are critical for structural and functional integrity Amie M. Morris...

Ngày tải lên : 07/03/2014, 04:20

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Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx

... However, the mechanistic roles of several of these residues are not described well and there is no example of mutational analysis of all of these residues in the same enzyme. To obtain an insight into ... circulans, whereas it may be mutated to asparagine without loss of activity in other family 18 chitinases [28,30]. Preliminary results of a comparative...

Ngày tải lên : 07/03/2014, 14:20

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Báo cáo khoa học: Leishmania donovani methionine adenosyltransferase Role of cysteine residues in the recombinant enzyme pptx

... [16]. Ó FEBS 2003 Cysteine residues in leishmanial MAT (Eur. J. Biochem. 270)31 Leishmania donovani methionine adenosyltransferase Role of cysteine residues in the recombinant enzyme Yolanda Pe ´ rez-Pertejo 1 , ... domain of each subunit, in the interface between the two dimers compri- sing the tetrameric structure [29]. This domain contains ﬁve cyst...

Ngày tải lên : 08/03/2014, 08:20

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Báo cáo khoa học: Different roles of functional residues in the hydrophobic binding site of two sweet orange tau glutathione S-transferases pdf

... of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248–254. 40 Laemmli UK (1970) Cleavage of structural proteins during the assembly of head of ... al. Functional role of the GST H -site residues FEBS Journal 277 (2010) 255262 ê 2009 The Authors Journal compilation ê 2009 FEBS 257 Different roles of functiona...

Ngày tải lên : 15/03/2014, 09:20

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Báo cáo khoa học: Kinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus – the role of conserved residues in the active site pdf

... 2010) doi:10.1111/j.1742-4658.2010.07685.x The hyperthermostable chitinase from the hyperthermophilic archaeon Pyrococcus furiosus has a unique multidomain structure containing two chi- tin-binding domains and two catalytic domains, and ... analyses of the catalytic domain of chitinase from Pyrococcus furiosus – the role of conserved residues...

Ngày tải lên : 15/03/2014, 11:20

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Báo cáo khoa học: Identiﬁcation of functional domains in the formyl peptide receptor-like 1 for agonist-induced cell chemotaxis doc

... domains in the formyl peptide receptor-like 1 for agonist-induced cell chemotaxis Yingying Le 1, 2 , Richard D. Ye 3 , Wanghua Gong 4 , Jianxiang Li 1 , Pablo Iribarren 1 and Ji Ming Wang 1 1 Laboratory ... G-protein-coupled receptor formyl peptide receptor- like 1. J Immunol 16 6, 14 48 14 51. 12 Quehenberger O, Prossnitz ER, Cavanagh SL, Cochrane CG &...

Ngày tải lên : 16/03/2014, 18:20

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Báo cáo khoa học: Identiﬁcation and characterization of important residues in the catalytic mechanism of CMP-Neu5Ac synthetase from Neisseria meningitidis potx

... important catalytic residues, indicating a role in binding the nucleotide into the active site [15,16]. The crystal structure of CNS from Neisseria meningitidis crystallized in the presence of ... stereo-view of the residues of interest (blue) in the active site of the CNS from Neisseria meningitidis containing CDP (yellow) (PDB 1EYR) [12] supe...

Ngày tải lên : 22/03/2014, 21:21

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Báo cáo khoa học: Characterization of mutations in crucial residues around the Qo binding site of the cytochrome bc1 complex from Paracoccus denitriﬁcans pdf

... despite the close prox- imity of the tyrosines to the Q o binding site. Most of the mutants studied here alter the spectral features of the quinone, indicating a variation of the hydrogen- bonding ... bc 1 complexes from other organisms. The mutated residues are highlighted in Fig. 1. Results Site- directed mutations in the Q o binding site Mutatio...

Ngày tải lên : 23/03/2014, 10:20

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Báo cáo hóa học: " Contribution of cysteine residues in the extracellular domain of the F protein of human respiratory syncytial virus to its function" docx

... of the individual cysteine residues in the extracellular domain in protein expression and cell fusion of the HRSV F protein and represents the first analysis of the contribution of the cysteine ... extracellular domain of the F protein of human parainfluenza virus 3 (hPIV3) has been solved [37]. The mature F protein of human...

Ngày tải lên : 20/06/2014, 01:20

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Different roles of functional residues in the hydrophobic binding site of two sweet orange tau pps

... of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248–254. 40 Laemmli UK (1970) Cleavage of structural proteins during the assembly of head of ... product reveals two completely different binding modes for the intermediate and the product, suggesting that a speciﬁc motion is associated with the collapse of the...

Ngày tải lên : 07/08/2014, 01:20

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Báo cáo lâm nghiệp: "Red deer density in the air-polluted area of forest ecosystems in the Krušné hory" pdf

... in the research area, mean values of the estimate of the red deer population density were deter- mined in the Jelení hora hunting district in 2007 and 2008 using the FSC method, viz 24 ± 23 individuals·km –2 ... (2): 59–63 59 JOURNAL OF FOREST SCIENCE, 57, 2011 (2): 59–63 Red deer density in the air-polluted area of forest ecosystems in the...

Ngày tải lên : 07/08/2014, 10:21

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Báo cáo khoa học: "Targeted surveillance to assess the presence of BSE in the age risk population of cattle slaughtered in Bursa, Turkey: preliminary results of an immunohistochemical detection study for the 2004-2005 period" pdf

Ngày tải lên : 07/08/2014, 20:23

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Báo cáo y học: "The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin" ppsx

... the numbers of arginine residues in the CDRs of these antibodies can lead to significant alterations in binding to DNA. Arginines in V H CDR3 often play a particularly important role in binding ... CDR3 of UK4V L hinders DNA binding sterically. A similar effect may be occurring with regards to the binding of UK4V L to CL. The effect of point...

Ngày tải lên : 09/08/2014, 06:22

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Báo cáo y học: " Fluorodeoxyglucose-positron emission tomography/computed tomography in the staging and evaluation of treatment response in a patient with Castleman''''s disease: a case report" pps

... tomography/ computed tomography in the staging and evaluation of treatment response in a patient with Castleman's disease: a case report Ettore Pelosi* 1 , Andrea Skanjeti †2 , Angelina ... in a patient with a mediastinal mass. Then, other authors reported new cases of the disease with different localisations, including abdominal and s...

Ngày tải lên : 11/08/2014, 23:21

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Báo cáo y học: "Large-scale discovery and validation of functional elements in the human genome" ppt

... goal of identifying all the functional elements in the human genome. The functional elements discussed at the meeting included protein-coding genes, reg- ulatory elements, RNA genes and DNA sequences ... [http:// www.genome.gov/10005107]. The consortium, organized and funded by the National Human Genome Research Insti- tute, is initially focusing on designated...

Ngày tải lên : 14/08/2014, 14:21

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