Báo cáo sinh học: "SnoPatrol: how many snoRNA genes are there" pdf

... Access Methodology Determination of suitable housekeeping genes for normalisation of quantitative real time PCR analysis of cells infected with human immunodeficiency virus and herpes viruses Sarah Watson 1 , ... Ref- erence gene selection for quantitative real- time PCR analy- sis in virus infected cells: SARS corona virus, Yellow fe...

Ngày tải lên: 18/06/2014, 18:20

... below). For information about publishing your research in Advances in Difference Equations go to http://www.advancesindifferenceequations.com/authors/instructions/ For information about other SpringerOpen ... we approximate the singular fourth-order BVP to singular second-order BVP by constructing an integral operator. In Section 3, the sufficient condition for the existence of single...

Ngày tải lên: 18/06/2014, 22:20

... as starvation, decrease signaling activity within the pathway, which in turn drives the worms into the developmentally arrested ‘dauer stage’ (DAF denotes ‘dauer forma- tion’). Dauer larvae alter ... DAF-16 is also disabled, the worms develop as normal. The clear implication is that in normal animals the insulin pathway has its effects on dauer formation via negative regulation of DAF-16. “Bu...

Ngày tải lên: 06/08/2014, 18:20

... current absence of knowledge of the physiological functions of at least half of all mammalian genes. Given that distinct and coordinate expression of a group of functionally related genes implies ... Number of genes defined as expressed in each of the 55 tissues, using criteria in (a). Number of expressing tissues Number of genes arcsinh (normalized intensity) Proportion...

Ngày tải lên: 06/08/2014, 18:21

... mountain of microarray data Hughes’ first concern was which genes to spot onto his microarray slides (see the ‘Background’ box). Researchers are Research news Co-regulation of mouse genes predicts ... preliminary functional annotation for thousands of genes of unknown function is a major advance.” The Hogenesch group is also creating an atlas of mammalian genes [5]. “Thi...

Ngày tải lên: 06/08/2014, 18:21

... provide rapid in vitro screens for analyzing new therapies and discovering means of achieving selective protection or targeted killing. In light of the ease of use of these in vitro and in vivo assays, ... Research article CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo Joerg Dietrich*, R...

Ngày tải lên: 06/08/2014, 18:21

... some of the aptamers tested have been shown to inhibit the function of their cognate targets and to cause phenotypes in the experimental models in which they were expressed. The use of peptide ... orders of magnitude. This work opens the way to an important extension of the therapeutic research applications of peptide aptamers, which are already used throughout th...

Ngày tải lên: 06/08/2014, 18:21

... acceptor 1a/1b 3 5′ splice acceptor 1a/1b 3 loxP X-NY X-Freiburg NFIA NFIB-NY NFIC NFI wild-type allele 1a/1b PGK-neo 3 LacZ 1a/1b 3 NFIB-Freiburg LacZ-neo 1a/1b 3 1a/1b PGK-neo 3 Transcript 1 2 3 1 21 3 + 1 ... 77:: 29 (P) 2 1-2 8. The X-NY strain, on the other hand, did not suffer from such severe impairments. Callosal agenesis as seen in the X-Freiburg strain was not noted in X-NY N...

Ngày tải lên: 06/08/2014, 18:21

... ORNs activated by an odor increases with odor concentration - thus creating a shifting odor representation in the antennal lobe. Despite this, Drosophila larvae can navigate towards an attractive odor source ... in Journal of Biology suggests that lateral inhibition in the Drosophila antennal lobe is similarly required for concentration-invariant perception of odors. Journal o...

Ngày tải lên: 06/08/2014, 18:21

... pheromone and other odorant signal processing and odor- quality discrimination. The anterior face of the moth is looking up toward the top of the figure. Sex pheromone information comes into the antennal ... odor- flux peaks of the plume s pheromone strands and the troughs of the clean air pockets are sharpened by the antennal lobe’s inhibitory circuitry, an...

Ngày tải lên: 06/08/2014, 18:21

... to Quantitative Genetics , 4 th edition. Harlow, Essex: Longman; 1996. Lynch M, Walsh B: Genetics and Analysis of Quantitative Traits . Sunderland, MA: Sinauer; 1998. Published: 17 April 2009 Journal of ... environments. These resources offer the prospect of elucidating the genetics of the interdependence of multiple phenotypes, and addressing the longstanding question of t...

Ngày tải lên: 06/08/2014, 19:20

... ooffffss Finding mechanisms that explain the difference in life span between males and females is hindered by our lack of understanding of the basic mechanisms of aging and underlying causes of ... 8 8:: 38 Published: 29 April 2009 Journal of Biology 2009, 8 8:: 38 (doi:10.1186/jbiol141) The electronic version of this article is the complete one and can be found on...

Ngày tải lên: 06/08/2014, 19:20

... compositions of the cells expressing connexin26 and connexion32 are slightly different. Collective physical properties Because high concentrations of anionic lipid are needed to affect channel ... interface, and similar charge interactions are likely to be important for other channels. It is also likely that the effects of anionic lipids on channel function follow directly...

Ngày tải lên: 06/08/2014, 19:21

... SnoPatrol: how many snoRNA genes are there? Journal of Biology 2010, 9:4. Page 4 of 4 that for many major taxonomic clades there are few or no known snoRNAs annotated. In the Archaea, annotated snoRNAs ... 1. snoRNA structure. The structure of a H/ACA snoRNA (left) and a C/D box snoRNA (right). The targets for RNA modification are shown in blue. The most important sn...

Ngày tải lên: 06/08/2014, 19:21

... finding of a major gene affecting fat androstenone level gives rise to new prospects for reducing incidence of boar taint by means of breeding. The average level of individuals ... results of a selection experiment based on an index associating fat androstenone level and bulbo-urethral gland size. In: Measurement and Prevention...

Ngày tải lên: 09/08/2014, 18:22