Báo cáo sinh học: " Chromatin ‘programming’ by sequence - is there more to the nucleosome code than %GC" pot

... observations, the extent to which genomic sequence directs chromatin structure through intrinsic Minireview Chromatin ‘programming’ by sequence - is there more to the nucleosome code than %GC? Amanda ... into the rules underlying histone-DNA interactions. For example, selections for tight-binding sequences provided the chromatin community with t...

Ngày tải lên: 06/08/2014, 19:21

... Consequently, these strains might be comparatively less prone to acquisition of resistance to antimicrobials – another advantage. But the country is now seeing slow but gradual rise of Bei- jing geno-family ... since more than 10, 000 BC) that continues to haunt the popu- lation here. Genotyping of patient isolates through the repertoire of variable-number tandem repeats (VN...

Ngày tải lên: 08/08/2014, 19:20

... is the space BMOΩ.InSection 3, we establish a relation between these two norms and L p -norm. We first present the local two- weight Poincar ´ e inequality for A-harmonic tensors. Then, as the ... estimates to such equation. In this paper, we extend some estimates that Ding has presented in 8 into the two-weight case. Our results are more general, so they can be used broadly....

Ngày tải lên: 21/06/2014, 20:20

... resulted to be lower in comparison to the mean fluore scence of the SW620 cells and consid- erably lower in comparison to the fluorescence of the SW620 cells we were able to detect in the enriched ... times, supporting the hypothesis of their neoplastic origin. An enrichment method based on EpCAM-positive selection would therefore not have been able to detect this fracti...

Ngày tải lên: 18/06/2014, 19:20

... K M is 1 5- to 30-fold larger compared to the wild-type at pH 4. The value of k cat reported in Table 1 is that obtained by fitting the data; the apparent maximal k cat in Fig. 1 is lower due to the ... and ⁄ or His92. While Asn91 is a ligand to the divalent metal of the mixed-valent di-iron center, the role of His92 in the catalytic mechanism is unknow...

Ngày tải lên: 23/03/2014, 13:20

... CAF-1 copurifies with histones displaying a similar pattern of lysine acetyla- tion to that reported for newly synthesized H4 [38]. There- fore, CAF-1 appears to act as a histone chaperone to deposit ... synthesized histones H3 and H4 onto newly replicated DNA in vitro (Fig. 2; [39]). The assembly of chromatin by CAF-1 occurs by a mechanism that is preferentially coupled to...

Ngày tải lên: 31/03/2014, 21:21

... density LMICs -0 .177** -0 .317** -0 .400** 0.101** MHICs -0 .643** -0 .792** -0 .878** 0.186** Nurse density LMICs -0 .026 0.044 -0 .284 *-0 .034 MHICs -0 .197 -0 .238 -0 .397 *-0 .032 Female literacy LMICs -0 .573** -0 .689** ... contribution to the acquisition of data and data analysis. KK made con- tribution to the acquisition of data in...

Ngày tải lên: 18/06/2014, 17:20

... many dis- ciplines. There are other attempts to develop an educa- tional context to Open Educational Resources (OER) in other disciplines – such as the peer -to- peer university [14]. There is a ... has led the business model to dominate in the educa- tion-for-capacity-building sector. Many well-meaning teachers are subverted to meet the goals of their institu- tions or...

Ngày tải lên: 18/06/2014, 17:20

... ART than did clinicians. These find- ings point to the limits to which tasks can be shifted, and underline the need to address the question of what tasks can be delegated, and to whom. Non-medical ... improving the design and analysis of future studies. Another important gap relates to the analysis of profes- sional, regulatory and other barriers to policy change in sp...

Ngày tải lên: 18/06/2014, 17:20

... classes. The underly- ing theme of the FETP model is that trainees ‘learn by doing’, and therefore the remaind er of the time is spent gaining hands-on experience through a field placement. This is ... FET P co-owner- ship by the MoH has ensured that training remains rele- vant to the needs of the ministry and the country’s health sector; hence graduates get placem...

Ngày tải lên: 18/06/2014, 17:20