Báo cáo sinh học: "Beyond toxicity: aryl hydrocarbon receptor-mediated functions in the immune system" docx

... compilation ê 2007 FEBS 3329 Modulation of aryl hydrocarbon receptor transactivation by carbaryl, a nonconventional ligand Susanna Boronat1, Susana Casado2, Jose´M. Navas2and Benjamin ... Casado S, Alonso M, Herrado´n B, Tarazona J & NavasJ (2006) Activation of the aryl hydrocarbon receptor by carbaryl: computacional evidence of the ability of carba-ryl to assume a planar ... function is bypassed by fusing aryl hydrocar-bon receptor to a heterologous DNA binding domain. This dual action of carbaryl, agonist and partial antagonist, was also observed by comparingcarbaryl...

... 9:2http://www.translational-medicine.com/content/9/1/2Page 10 of 11 RESEA R C H Open AccessInvolvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteinsTonia ... Buonomo et al.: Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins. Journal of Translational Medicine2011 9:2.Submit ... subsequentlyleading to progression of the cell into the S-phase [14].Furthermore, E7 binds to inhibitors of cyclin-dependentkinases (p16, p21), increasing the level of phosphory-lated pRb. In t his way, HPV...

... changes in service quality after two rounds of forma-tive supervision in four districts of Senegal. Supervision and quality Approaches to improving quality of care have usuallyfocused on training ... defined in the supervision checklist.To measure community involvement in improving serviceExample of page 1 of infection prevention in supervision checklistFigure 1Example of page 1 of infection ... of the most promising aspects of formative supervi-sion is the participation of the community in evaluatingand improving service quality. Through their involvement in developing action plans,...

... conditions in Uganda and abroad were comparable. Intent to migrate We found 70 percent of nursing students expressed an intent to migrate out of Uganda. The percentage of nurs-ing students desiring to ... groups of students intending to emigrate to the U.K. or U.S. were of having a positiveoutlook of working conditions abroad, including findinga job matched to skill, ability to increase in rank, ... think nurseswill think of leaving. People want to stay with their fami-lies, but then they sacrifice to go."Urban-inclined nursing student versus rural-inclined nursing studentThose inclined...

... Discussions within the United States of America began among federal policymakers, medical and specialty societies, and educators,leading to the American Academy of Pediatrics (AAP)establishing a multi-organizational ... survey of ‘inactive’ physicians in the United States of America: enticements to reentryEthan A Jewett1, Sarah E Brotherton2*, Holly Ruch-Ross3AbstractBackground: Physicians leaving and reentering ... by a grant from the American Medical AssociationWomen Physicians Congress through the Joan F. Giambalvo MemorialScholarship, to aid in data acquisition, survey printing and mailing, andstatistical...

... of hantavirus antigens in S. araneus in the former Yugoslavia and Russia[15-17]. The important distinction is that we now havesequence data to substantiate the existence of a hantavirus in the ... purposes) in Hungary and Finland (S. Arai and R. Yanagihara,unpublished observations).Found in woodlands, grasslands and hedgelands through-out Northern Europe, including Scandinavia and GreatBritain ... 5'-TAGTAGTAGACTCC-3' andSWS S1093F: 5'-TACAGCTGAGGAGAAGC-3' for the Ssegments; OSM55 and SWS L1351F: 5'-CAAGGCCCAG-CAAAACATAC-3' for the L segment; and OSV697: 5'-GGACCAGGTGCADCTTGTGAAGC-3'...

... and3GPP-LTE. Therefore, we will focus on the maximizing energy efficiency problem in the downlink MIMO systems in this article.Previous works mainly focused on maximizing energy efficiency in the single-input ... single-output (SISO) systems[3–7] and point to point single user (SU) MIMO systems [8–10]. In the uplink TDMA SISO channels, the optimal transmission rate was derived for energy saving in the ... increase the inter-user interference, in which the multiplexing gain makes transmit power saving, but inter-user interference inducestransmit power wasting. In order to maximize BPJ-EE, the trade-off...

... Medicine 2011, 4:52http://www.intjem.com/content/4/1/52Page 3 of 3 CAS E REP O R T Open Access Meningeal carcinomatosis diagnosed during stroke evaluation in the emergency departmentDerek R ... carcinomatosis diagnosed during stroke evaluation in the emergency department.International Journal of Emergency Medicine 2011 4:52.Submit your manuscript to a journal and benefi t from:7 Convenient online ... direct the physician to a neuro-logic etiology. The CT of the head confirmed the pre-sence of a structural brain abnormality. MRI of the brainconfirmed the diagnosis of meningeal carcinomatosis, and...

... difficultResearch news Tracking evolution’s footprints in the genomeJonathan B Weitzman BioMed CentralJournalof Biology The strategy of using ‘phylogenetic footprinting’ to find regulatory sites ... AlbinSandelin for his thesis project studying the binding similarities of transcrip-tion factors in the same structuralfamilies,” says Wasserman. (See the ‘Behind the scenes’ box for further ... tolocate and explore the regulatory ele-ments in their chosen genome (see The bottom line’ box for a summaryof their work).Predicting binding sitesUnderstanding the principles thatgovern...

... < D0) and swapping a random pair of branches.AAddddiittiioonnaall ddaattaa ffiilleessAdditional data file 1 contains a list of species (59 bacterialand 41 archaeal) used for the FOL construction. ... simulation of a BBB at a depth of 0.8 orgreater is meaningless within the context of the presentanalysis or any imaginable further analysis, because the archaea and bacteria are thought to be the ... construction. Additionaldata file 2 contains all the phylogenetic trees. Additionaldata file 3 contains a list of the 102 COGs that arerepresented in at least 90 of the1 00 selected archaea andbacteria.AAcckknnoowwlleeddggeemmeennttssWe...

... role in promoting (though not in initiating) the differentiation of TH17 cells, and more importantly, in inducing them to secrete the cytokine interleukin (IL)-22 (a cytokine impli-cated in ... functional subsets, distinguished by the different cytokines they produce (indicated under each CD4 T cell type): the cytokines act on other immune cells, activating them in turn. The four known subsets ... further subdivided into four clearly defined subsets with distinct functions that are mediated by the distinct cytokines they secrete and that act on other immune cells (Figure 1), including...

... treatments’, host seeds’ and ’rearing host ; table II) wasstatistically significant. Original article Laboratory evolution of host plant utilization in the bean weevil(Acanthoscelides ... than those in the Phaseolus lines.This finding was statistically confirmed by the results of the factorial analysis of variance (table II). In addition, the host seeds ... searching for the preferred host, thus reducinglaying time. Also, the lower magnitude of these correlations in ’no-choice’ linesmay be explained through selection favouring...

... approach in the analysis of conformation traits in the Montbeliarde cattle breed. A completelyheteroskedastic univariate mixed model allowing for genotype x environment inter-action ... Z!iZli and parts of the inverse of the coefficient matrix. For instance, in the case of model (a), six traces, three of them involving products of symmetric matrices(X’Xj ... easilycomputed: For computing the trace of these matrices, one can use the Cholesky decompo-sition of the coefficient matrix C. For instance, for the computation of tr 4, we usethe...

... Biology and Medical ModellingOpen AccessResearchCommon angiotensin receptor blockers may directly modulate the immune system via VDR, PPAR and CCR2bTrevor G Marshall*1, Robert E Lee2 and ... from the 1-hydroxyl oxy-gen to the aminoacetal of ARG274 and the hydroxyl ofSER237, and another pair from the ligand's O3 oxygen toSER278 and TYR143.Figure 6 shows that the VDR agonist ... hydrogen bond between the oxygen of itstriol group, the imidazole of HIS397, and the imidazoleof HIS305. The 3-hydroxyl-oxygen is hydrogen-bonded toTYR 143 and SER278, while the 1-hydroxyl-oxygen...