Báo cáo sinh học: "Shrinkage control: regulation of insulin-mediated growth by FOXO transcription factors" ppt

... transcrip- tion of a number of target genes. Growth control by FOXO factors Could FOXO- regulated transcription play a role in growth regulation by the insulin/PI 3-kinase pathway? Several lines of evidence ... understanding of the multiple layers of insulin-mediated growth regulation. Control of gene expression by FOXO factors in response to insulin allows...

Ngày tải lên: 06/08/2014, 18:20

... acts downstream of IL-15 in the regulation of memory CD8 T-cell homeostasis. Blood 2006, 107:3992-3999. 26. Sandalova E, Wei CH, Masucci MG, Levitsky V: Regulation of expression of Bcl-2 protein ... biology, in view of proteomic experiments demon- strating that a single miRNA can directly repress the production of hundreds of proteins in mammalian cells, through both downreg...

Ngày tải lên: 18/06/2014, 19:20

... concerning the stability of 1.5 in the sense of the JMRassias stability of functional equations controlled by the mixed product- sum of powers of norms introduced by J. M. Rassias 26 and ... stability of the linear functional equation,” Proceedings of the National Academy of Sciences of the United States of America, vol. 27, pp. 222–224, 1941. 8 T. Aoki, “On the...

Ngày tải lên: 21/06/2014, 16:20

... recommended by the WHO antibiotics. Nevertheless sporadic cases of a kind of antibiotic resistance have been reported [7,8]. The aim of this essay was to determine the antibiotic susceptibilities of the ... Laboratory of Clinical Bacteriology, Parasitology, Zoonoses, and Geographical medicine of the University of Crete. Methods A number of 74 strains were included in this re...

Ngày tải lên: 08/08/2014, 19:20

... amplitude of the slow phase (extent of ligation) is independent of the concentration of ATP, approaching % 90% of the total concentration of the ndsDNA substrate in the reaction mixture. Effect of Mg 2+ concentration Mg 2+ is ... member of the same superfamily of nucleotidyl- transferases [34,35]. In the cell, capping of the 5¢-end of mRNA ensures protection from degrada...

Ngày tải lên: 21/02/2014, 00:20

... q 1 ,q 2 are weak limit points of {x n }. Lemma 2.9 the demiclosedness principle of nonexpansive mappings 13. Let T be a nonexpansive selfmapping of a closed convex subset of E of a uniformly convex ... Proceedings of the National Academy of Sciences of the United States of America, vol. 54, pp. 1041–1044, 1965. 14 C. Moore, “A double-sequence iteration process for fixe...

Ngày tải lên: 22/06/2014, 11:20

... results of these activities. It should be noted that this was not a pilot project, but part of routine pro- gramme management by the Ministry of Health. Case description The systematic development of ... 2000-2002, followed by a project proposal for funding of the plan. The funding proposal was approved by the Dutch government. The overall goal of the plan was to improve the...

Ngày tải lên: 18/06/2014, 17:20

... expression of estrogen receptor-a (ERa) is autoregulated by miR-18a, -19b and -20b, which in turn are upregulated by the activation of ERa. This mechanism of regulation provides a wide range of coordinated ... the fine-tuning of p53 activity [45,46]. miR-34a is also induced by a p53-independent pathway: ELK1, which is a member of the ETS family of transcription factors,...

Ngày tải lên: 14/02/2014, 19:20

... physiological regulation of sirtuins by NAD + metabolites and by enzymes in the NAD + salvage path- way. In addition, we will cover the use and efficacy of small molecule inhibitors and activators of sirtuin ... Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y et al. (2004) Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303, 2...

Ngày tải lên: 20/02/2014, 01:20

... mechanism of regulation of both domains involves a common iron dependent process [74,75,79]. Regulation of HIFa subunits by oxygen-dependent prolyl and asparaginyl hydroxylation A variety of oxygen ... Post- transcriptional regulation of vascular endothelial growth factor by hypoxia. J. Biol. Chem. 271, 2746–2753. 120. Shima, D.T., Deutsch, U. & D’Amore, P.A. (1995)...

Ngày tải lên: 20/02/2014, 23:20