Báo cáo sinh học: "Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements " doc

... Minireview Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements Zhaolei Zhang and Mark Gerstein Address: Department of Molecular Biophysics and Biochemistry, ... sites, and the technique itself in this context has become known as phylogenetic footprinting [15,16], a term inspired by the wet-lab technique of DNAse footpr...

Ngày tải lên: 06/08/2014, 18:20

... Interestingly, the gi parameters of the average curves were similar to the mean values of the g i of the ten lines. Wing/thorax ratio The gi parameters of the third degree ... to the fourth degree and gave TMS values of 13.5 °C (females) and 12.4 °C (males) for the wing, and of 16.1 °C (females) and 13.2 °C (males) for...

Ngày tải lên: 09/08/2014, 18:22

... between the N- and C-termini of the AR, and interferes with the binding of the coactivator TIF2 [86,91]. There is evidence that interaction between the FXXLF (X = any amino acid) motif of the TAD and the ... Injection of anti-actin Ig into the nuclei of salamander oocytes results in contraction of the lateral loops and the inhi- bition of transcriptio...

Ngày tải lên: 07/03/2014, 01:20

... an MOI of 100 infectious units [24]. The construction and characterization of the mutant PAdV-3s has been described [19,20]. At 6 h post infection, the cells were har- vested and processed for the ... reduce the activity of luciferase reporter gene. The results of the reporter gene expression indicated that E1B large reduced the NF-κB activated gene expression an...

Ngày tải lên: 18/06/2014, 18:20

... either parent, and can be thought of as regulation in trans. On the other hand, a downregulation or upregulation of only one parental allele of the pair in the new hybrid environment suggests the existence ... contribu- tions of the parental alleles; dominance was detected by the suppression of genes in the allopolyploid that are strongly expressed in one parent and...

Ngày tải lên: 06/08/2014, 19:20

... on their own communication style, and by increasing their awareness of the gaps between their own views and the views of the different actors with whom they interact: patients, communities and ... by assessing the profes- sional career of all doctors who participated in the train- ing from 2003 to 2007. Baseline data of retention of rural doctors prior to the int...

Ngày tải lên: 18/06/2014, 17:20

... resources; and four, organizational resources. The structural aspects of EmOC and the inter- personal constituents of the EmOC process were easily identified. The clinical aspects of EmOC, where the ... AND "quality health care OR quality care" AND "developing countries". Based on the advice of one of the authors (PF), an expert in the fie...

Ngày tải lên: 18/06/2014, 17:20

... conceived of the study, participated in the design and coordination, and helped to draft the manuscript. SC and MP participated in the conceptualization and design of the study and helped to draft the manuscript. ... 8 of 11 andUP,andacrosspublicandprivatesectors[12], items were added to examine these aspects of the work environment: one item on political inter...

Ngày tải lên: 18/06/2014, 17:20

... are necessary and sufficient to mediate protein-protein inter- action. We then investigated whether the integrity of the coiled coil region of NP is important for the binding of NP to the polymerase cofactor ... for the homooligomerization of NP, formation of NP-induced intracellular inclusions, interac- tion of NP with VP35 and for the function of NP in RNA synt...

Ngày tải lên: 18/06/2014, 18:20

... hypermethyla- tion of the neu promoter and loss of neu both at mRNA and protein levels [3,5], resulting in escape of the tumor from further neu-specific immune responses. On the clinical front, ... didnotshowanychangein the expression of HER-2/neu [10]. Such failure of the LNCaP to respond to IFN-g was later shown to be due to the lack of JAK1 expression [11]. The...

Ngày tải lên: 18/06/2014, 19:20