Play how it shapes the brain opens the imagination and invigorates the soul stuart brown
... serious’ but at the same time absorbing the player intensely and utterly. It is an activity connected with no material interest, and no profit can be gained from it. It proceeds within its own proper ... in a sandbox. For Salk and other scientists I talked to, the thrill of their play was amplified because their particular sandboxes were filled with expensive toys, and t...
Ngày tải lên: 20/07/2014, 20:39
... IRX LEAPS The aggregate position and exercise limit is 5,000 contracts on either side of the market. FVX, TNX, TYX, and their respective LEAPS The aggregate position and exercise limit is 25,000 ... maturity and the yield of a Treasury bond with 29-3/4 years to maturity than there is between the yield of a 13-week T-Bill with 3 months to maturity and the yield of a 13-we...
Ngày tải lên: 06/03/2014, 14:20
... of 0.33 A ˚ . The electron density in the area local to the substitution is shown in Fig. 4. The positions of catalytic residues and all other residues local to the substitution site do not differ ... at this site was shown to lower the N-glycosidase activity 37.5-fold, and cytotoxicity of the reassociated holotoxin by 30-fold, without affecting the overall structure or t...
Ngày tải lên: 19/02/2014, 12:20
The Power of “Independence”: Defending and Extending the Jurisdiction of Accounting in the UK pdf
... parried, the claim to independence, and the status and power that it bestows, may become discredited and devalued, with consequences for the reputation of accountants and their capacity to secure and ... actual and anticipated criticism from the DTI inspectors, politicians and the press 24 . The explicit purpose of this committee was "to satisfy our critic...
Ngày tải lên: 06/03/2014, 15:21
Báo cáo khoa học: The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B1 and B2 bradykinin receptors potx
... C-terminus of the G a subunit G t and of the Gc subunit of transducin inter- acted with rhodopsin and kept it in an activated state [28]. This interaction, however, was abolished in mutants with replacements ... IP responses obtained with the wild-type receptors and the chimera let us speculate that each wild-type helix 8 may be specific either for selected bc subunits or for e...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid b-protein doc
... ubiquitination confer specificity to the ubiquitin system by directly interacting with the sub- strate proteins and helping to transfer ubiquitin to them. Therefore, to determine whether NCT is the substrate ... Syno- violin and NCT were immunoprecipitated with anti-FLAG antibody and immunode- tected with anti-NCT antibody. (B) The same cell lysates were immunoprecipitated with a...
Ngày tải lên: 23/03/2014, 04:20
The Complete Book of Alphabet and Numbers (The Complete Book Series) doc
Ngày tải lên: 23/03/2014, 11:20
the united nations security council and war the evolution of thought and practice since 1945 aug 2008
... arrangements or agencies and their activities are consistent with the Purposes and Principles of the United Nations. Article 53 addresses the delicate question of how the Security Council and regional arrangements ... Although it was the General Assembly that established the Commission, the resolution speciWed that the new body was to report to the Security Council...
Ngày tải lên: 11/06/2014, 09:44
Select the bad habit you have and give the reason why you have that habit pot
Ngày tải lên: 23/06/2014, 00:20