Neurochemical Mechanisms in Disease P82 ppsx
Neurochemical Mechanisms in Disease P82 ppsx
... clearing tissue deposits and clinical effi- cacy in modifying disease phenotype when used as a singular approach remains to be established. As the drugs (isofogamine for Gaucher disease and the imino sugar ... wlukiw@lsuhsc.edu 799 J.P. Blass (ed.), Neurochemical Mechanisms in Disease, Advances in Neurobiology 1, DOI 10.1007/978-1-4419-7104-3_24, C Springer Science+Business M...
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Neurochemical Mechanisms in Disease P1 ppsx
... material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com) Contents Mechanisms Versus Diagnoses 1 John P. Blass Molecular Mechanisms ... Neurodegenerative Disorders: Parkinson’s Disease and Alzheimer’s Disease 243 Ivan Bodis-Wollner and Herman Moreno NF-κB in Brain Diseases 293 Cheng-Xin Gong Trinucleotide-Expansion D...
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Neurochemical Mechanisms in Disease P12 ppsx
... deficiencies, examines the role of vitamins in cellular function, and reviews current mechanisms involved in the pathogenesis of brain dysfunction in vitamin deficiencies. 2Thiamine(VitaminB 1 ) Thiamine is ... locus in autosomal dominant parkinsonism: confirmation of linkage and further delineation of the disease- containing interval. Am J Hum Genet 74:11–19 Zuscik MJ, Sands S, Ross...
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Neurochemical Mechanisms in Disease P38 ppsx
... In normal brain tissue caspase-1 is activated within molecular platforms called in ammasomes. Key proteins of in ammasomes are proteins containing caspase recruitment domains (CARDS), or pyrin ... producing proinflammatory cytokines. These cytokines then enter the brain by volume diffusion. Third, the overflow of cytokines in the systemic circulation can gain entry to the brain via cytoki...
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Neurochemical Mechanisms in Disease P52 ppsx
... JM, Wang R (2008) In vivo characterization of the effects of human hemokinin-1 and human hemokinin-1(4–11), mammalian tachykinin peptides, on the modulation of pain in mice. Brain Behav Immun 22:850–860 Fu ... acid inhibits synaptic and acidic amino acid-induced responses in the rat hippocampus and spinal cord. Brain Res 273: 170–174 Gao L, Yu LC (2004) Involvement of opioid receptors...
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Neurochemical Mechanisms in Disease P54 ppsx
... Nrf2-mediated haeme oxygenase-1 up-regulation induced by cobalt protoporphyrin has antinociceptive effects against in ammatory pain in the formalin test in mice. Pain 137:332–339 Rosen A, Zhang YX, Lund ... microinjected into the periaqueductal gray matter induces antinociception and is released following morphine administration. Brain Res 1001:87–94 Rossier J, French ED, R ivier C, Ling...
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Neurochemical Mechanisms in Disease P71 ppsx
... oligomers in protein misfolding diseases. J Biol Chem 279:46363–46366 Kelleher SL, Lonnerdal B (2002) Zinc transporters in the rat mammary gland respond to marginal zinc and vitamin A intakes during ... zinc and its functional significance in the brain. Brain Res Brain Res Rev 34:137–148 Takeda A, Minami A, Takefuta S, Tochigi M, Oku N (2001) Zinc homeostasis in the brain of adult rats...
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Neurochemical Mechanisms in Disease P81 ppsx
... lipofuscinosis (NCL) Late-infantile NCL Congenital NCL protective protein/cathepsin A SUMF-1 Acid lipase NPC1; HE1 Sialin Cystinosis Cathepsin K Palmitoyl-protein thioesterase Pepstatin-insensitive ... (protective protein/cathepsin A) Multiple sulfatases (Austin disease) Wolman disease, CESD (cholesterol ester storage disease) Niemann–Pick disease type C Salla, ISSD Cystinosis Pycnodys...
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Neurochemical Mechanisms in Disease P84 ppsx
... in, 274 J.P. Blass (ed.), Neurochemical Mechanisms in Disease, Advances in Neurobiology 1, DOI 10.1007/978-1-4419-7104-3, C Springer Science+Business Media, LLC 2011 823 Genetic Signaling in ... as predictors of response to chemotherapy in gliomas. Curr Opin Oncol 19:606–611 Johansson Swartling F (2008) Identifying candidate genes involved in brain tumor formation. Ups J M...
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Neurochemical Mechanisms in Disease P86 pps
... 299–301 in brain diseases, 307 domains, 298 in glial cells, 306 in Huntington’s disease (HD), 309–310 inhibitors, 297 in ischemic and traumatic brain injury, 307–308 in learning and memory, 305 in ... 364 Receptor-interacting kinase-1 (RIP1), 24 Reelin, 392 Rel family, 297 polypeptides, 301 Remyelination, in MS, 545 Renin-angiotensin system (RAS), 444 Retina, 250, 260 dopamine...
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