Chapter 109 Disorders of Platelets and Vessel Wall (Part 7) ppt
Chapter 109. Disorders of Platelets and Vessel Wall (Part 7) ppt
... number of young red blood cells, and
nucleated RBCs are often present, which is thought to be due to infarction in the
microcirculatory system of the bone marrow.
Chapter 109. Disorders of Platelets ...
and Vessel Wall
(Part 7)
Thrombotic Thrombocytopenic Purpura
TTP and HUS were previously considered overlap syndromes. However, in
the past few years the pa...
Chapter 109. Disorders of Platelets and Vessel Wall (Part 5) ppt
... in treatment of HIT, with prompt discontinuation
of heparin and use of alternative anticoagulants. Thrombosis is a common
complication of HIT, even after heparin discontinuation, and can occur ... Introduction of warfarin alone in the setting of HIT or HITT may
precipitate thrombosis, particularly venous gangrene, presumably due to clotting
activation and severely reduced...
Chapter 109. Disorders of Platelets and Vessel Wall (Part 10) pptx
... the setting of upper urinary tract bleeding, due to the risk of
ureteral obstruction.
Disorders of the Vessel Wall
The vessel wall is an integral part of hemostasis, and separation of a fluid ... replaced.
von Willebrand Disease: Treatment
The mainstay of treatment for type 1 vWD is 1-deamino-8-D-
arginine vasopressin (DDAVP, or desmopressin), which results in rele...
Chapter 109. Disorders of Platelets and Vessel Wall (Part 1) docx
... enlarges. Platelets are physiologically very
Chapter 109. Disorders of Platelets
and Vessel Wall
(Part 1)
Harrison's Internal Medicine > Chapter 109. Disorders of Platelets and
Vessel Wall ... Platelets and
Vessel Wall
Disorders of Platelets and Vessel Wall: Introduction
Hemostasis is a dynamic process in which the platelet a...
Chapter 109. Disorders of Platelets and Vessel Wall (Part 2) ppsx
...
macrothrombocytopenia. D.
Schistocytes and decreased platelets in
microangiopathic hemolytic anemia.
Chapter 109. Disorders of Platelets
and Vessel Wall
(Part 2)
Thrombocytopenia
Thrombocytopenia ... from one or more of three processes: (1)
decreased bone marrow production; (2) sequestration, usually in an enlarged
spleen; and/ or (3) increased platelet...
Chapter 109. Disorders of Platelets and Vessel Wall (Part 3) pot
... production and platelet
Chapter 109. Disorders of Platelets
and Vessel Wall
(Part 3)
Approach to the Patient: Thrombocytopenia
The history and physical examination, results of the CBC, and review ... CBC, and review of the
peripheral blood smear are all critical components in the initial evaluation of the
thrombocytopenic patients (Fig. 109- 2). The ove...
Chapter 109. Disorders of Platelets and Vessel Wall (Part 4) potx
...
thrombocytopenia, timing of platelet count drop, thrombosis and other sequelae
such as localized skin reactions, and other cause of thrombocytopenia not evident.
Figure 109- 3
... with bleeding and, in fact, markedly increases the risk of
thrombosis. HIT results from antibody formation to a complex of the platelet-
specific protein platelet factor 4 (PF4) and heparin...
Chapter 109. Disorders of Platelets and Vessel Wall (Part 6) potx
... anomaly and Sebastian, Epstein's, and Fechtner syndromes, all of which
have distinct distinguishing features. A common feature of these disorders is large
Chapter 109. Disorders of Platelets ... Platelets
and Vessel Wall
(Part 6)
Immune Thrombocytopenic Purpura: Treatment
The treatment of ITP utilizes drugs that decrease reticuloendothelial uptake
o...
Chapter 109. Disorders of Platelets and Vessel Wall (Part 8) potx
... Disorders of Platelet Function
Inherited Disorders of Platelet Function
Inherited platelet function disorders are thought to be relatively rare,
although the prevalence of mild disorders of ... for such disorders is suboptimal. Rare qualitative disorders
include the autosomal recessive disorders Glanzmann's thrombasthenia (absence
of the platelet GpIIbIIIa rec...
Chapter 109. Disorders of Platelets and Vessel Wall (Part 9) pdf
...
1
Nl or
up
down
down
down
Normal
distribution,
Chapter 109. Disorders of Platelets
and Vessel Wall
(Part 9)
von Willebrand Disease
vWD is the most common inherited bleeding disorder. ... subtypes of type
2 (Table 109- 2). By far the most common type of vWD is type 1 disease, with a
parallel decrease in vWF protein, vWF function, and FVIII levels, acc...
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