Chapter 097 Paraneoplastic Neurologic Syndromes (Part 2) potx

... Chapter 097. Paraneoplastic Neurologic Syndromes (Part 2) Pathogenesis Most PNDs are mediated by immune responses triggered ... the resistance of many of these conditions to therapy. Table 97- 2 Paraneoplastic Antineuronal Antibodies, Associated Syndromes and Cancers Antibody Syndrome Associated Cancers Anti-Hu ... nervous system (CNS), many antibody-associated...

Ngày tải lên: 07/07/2014, 04:20

... in 30–50% of patients with thymoma or sclerotic myeloma. Table 97-1 Paraneoplastic Syndromes of the Nervous System Syndromes of the brain, brainstem, and cerebellum Focal encephalitis ... Paraneoplastic cerebellar degeneration Opsoclonus-myoclonus Syndromes of the spinal cord Subacute necrotizing myelopathy Motor neuron dysfunction Myelitis Stiff-person syndrome S...

Ngày tải lên: 07/07/2014, 04:20

... Chapter 097. Paraneoplastic Neurologic Syndromes (Part 3) Neuronal cell-surface antigens can be the target of antibodies in some patients with paraneoplastic encephalitis. ... antigens are unknown. These include several syndromes of inflammatory neuropathies and myopathies. In addition, many patients with typical PND syndromes are antibody- negative. For still other...

Ngày tải lên: 07/07/2014, 04:20

... synthesis of IgG, and a variable presence of oligoclonal bands. Chapter 097. Paraneoplastic Neurologic Syndromes (Part 4) PND of the Central Nervous System and Dorsal Root Ganglia ... can occur with other disorders [e.g., nonparaneoplastic limbic encephalitis with antibodies to VGKC, human herpesvirus (HHV) 6 encephalitis] (Fig. 97 -2). The CSF profile of patients with...

Ngày tải lên: 07/07/2014, 04:20

... present with Chapter 097. Paraneoplastic Neurologic Syndromes (Part 5) Specific Paraneoplastic Neurologic Syndromes (Table 97-3) Table 97-3 Antibody- Associated Paraneoplastic and Nonparaneoplastic ... (Table 97-3) Table 97-3 Antibody- Associated Paraneoplastic and Nonparaneoplastic Syndromesa Antibodies Paraneoplastic

Ngày tải lên: 07/07/2014, 04:20

... of these antibodies are shown in Table 97-2. Figure 97-3 Chapter 097. Paraneoplastic Neurologic Syndromes (Part 6) Paraneoplastic Encephalomyelitis and Focal Encephalitis The term ... Several clinicopathologic syndromes may occur alone or in combination: (1) cortical encephalitis, which may present as "epilepsia partialis continua"; (2) limbic encephali...

Ngày tải lên: 07/07/2014, 04:20

... monoclonal protein in serum or CSF. Chapter 097. Paraneoplastic Neurologic Syndromes (Part 7) Encephalitis and Encephalomyelitis: Treatment Most types of paraneoplastic encephalitis and encephalomyelitis ... large series of patients with antibody-positive paraneoplastic cerebellar degeneration show that this disorder rarely improves with any treatment. Paraneoplastic...

Ngày tải lên: 07/07/2014, 04:20

... A benefit of IVIg has been demonstrated for the nonparaneoplastic disorder but remains to be established for the paraneoplastic syndrome. Paraneoplastic Sensory Neuronopathy or Dorsal Root ... metastasis to vertebral bodies and pelvis, deposits of amyloid in peripheral nerves, and paraneoplastic mechanisms. The paraneoplastic variety has several distinctive features. Approximately...

Ngày tải lên: 07/07/2014, 04:20

... feature of encephalomyelitis, serum anti-Hu and anti-CV 2 /CRMP5 Chapter 097. Paraneoplastic Neurologic Syndromes (Part 9) Vasculitis of the nerve and muscle causes a painful symmetric ... Paraneoplastic Visual Syndromes This group of disorders involves the retina and, less frequently, the uvea and optic nerves. The term cancer-associated retinopathy is used to descr...

Ngày tải lên: 07/07/2014, 04:20

... Chapter 026. Confusion and Delirium (Part 2) Epidemiology Delirium is a common disease, but its reported incidence

Ngày tải lên: 06/07/2014, 13:20