Chapter 097 Paraneoplastic Neurologic Syndromes (Part 1) potx
Chapter 097. Paraneoplastic Neurologic Syndromes (Part 1) potx
... in 30–50% of patients
with thymoma or sclerotic myeloma.
Table 97-1 Paraneoplastic Syndromes of the Nervous System
Syndromes of the brain, brainstem, and cerebellum
Focal encephalitis ...
Paraneoplastic cerebellar degeneration
Opsoclonus-myoclonus
Syndromes of the spinal cord
Subacute necrotizing myelopathy
Motor neuron dysfunction
Myelitis
Stiff-person syndrome
S...
Chapter 097. Paraneoplastic Neurologic Syndromes (Part 2) potx
... Chapter 097. Paraneoplastic
Neurologic Syndromes
(Part 2)
Pathogenesis
Most PNDs are mediated by immune responses triggered ... conditions to therapy.
Table 97-
2 Paraneoplastic Antineuronal Antibodies, Associated
Syndromes and Cancers
Antibody Syndrome Associated
Cancers
Anti-Hu
(ANNA -1)
PEM (including cortical,
limbic, ... dysfunction, myelitis),
PSN, autono...
Chapter 097. Paraneoplastic Neurologic Syndromes (Part 3) doc
... Chapter 097. Paraneoplastic
Neurologic Syndromes
(Part 3)
Neuronal cell-surface antigens can be the target of antibodies in some
patients with paraneoplastic encephalitis. ... antigens are
unknown. These include several syndromes of inflammatory neuropathies and
myopathies. In addition, many patients with typical PND syndromes are antibody-
negative.
For still other...
Chapter 097. Paraneoplastic Neurologic Syndromes (Part 4) docx
... synthesis of IgG, and a variable presence of
oligoclonal bands.
Chapter 097. Paraneoplastic
Neurologic Syndromes
(Part 4)
PND of the Central Nervous System and Dorsal Root Ganglia ... important to rule out neurologic complications
due to the direct spread of cancer, particularly metastatic and leptomeningeal
disease. In most PNDs the MRI findings are nonspecific. Par...
Chapter 097. Paraneoplastic Neurologic Syndromes (Part 5) pdf
... present with
Chapter 097. Paraneoplastic
Neurologic Syndromes
(Part 5)
Specific Paraneoplastic Neurologic Syndromes
(Table 97-3)
Table 97-3 Antibody-
Associated Paraneoplastic and Nonparaneoplastic ...
(Table 97-3)
Table 97-3 Antibody-
Associated Paraneoplastic and Nonparaneoplastic
Syndromesa
Antibodies
Paraneoplastic
Chapter 097. Paraneoplastic Neurologic Syndromes (Part 6) doc
... of these antibodies are shown in Table 97-2.
Figure 97-3
Chapter 097. Paraneoplastic
Neurologic Syndromes
(Part 6)
Paraneoplastic Encephalomyelitis and Focal Encephalitis
The term ... loss, gliosis)
beyond the symptomatic regions. Several clinicopathologic syndromes may occur
alone or in combination: (1) cortical encephalitis, which may present as "epilepsia...
Chapter 097. Paraneoplastic Neurologic Syndromes (Part 7) pps
... monoclonal protein in serum or
CSF.
Chapter 097. Paraneoplastic
Neurologic Syndromes
(Part 7)
Encephalitis and Encephalomyelitis: Treatment
Most types of paraneoplastic encephalitis and encephalomyelitis ... in anti-Ri-associated syndromes is breast cancer.
teratoma of the ovary, and the encephalitis that associates with VGKC antibodies
in some patients with thymoma...
Chapter 097. Paraneoplastic Neurologic Syndromes (Part 8) pptx
... A benefit of IVIg has been demonstrated for the nonparaneoplastic
disorder but remains to be established for the paraneoplastic syndrome.
Paraneoplastic Sensory Neuronopathy or Dorsal Root ... metastasis to vertebral bodies and pelvis, deposits of amyloid in
peripheral nerves, and paraneoplastic mechanisms. The paraneoplastic variety has
several distinctive features. Approximately...
Chapter 097. Paraneoplastic Neurologic Syndromes (Part 9) ppt
... feature of encephalomyelitis, serum anti-Hu and anti-CV
2
/CRMP5
Chapter 097. Paraneoplastic
Neurologic Syndromes
(Part 9)
Vasculitis of the nerve and muscle causes a painful symmetric ... Paraneoplastic Visual Syndromes
This group of disorders involves the retina and, less frequently, the uvea
and optic nerves. The term cancer-associated retinopathy is used to descr...
Chapter 020. Hypothermia and Frostbite (Part 1) potx
... glycogen stores and gluconeogenesis, as well as a
Chapter 020. Hypothermia and Frostbite
(Part 1)
Harrison's Internal Medicine > Chapter 20. Hypothermia and Frostbite
Hypothermia ... diabetic ketoacidosis, and lactic acidosis can lead to
altered hypothalamic thermoregulation.
Neurologic injury from trauma, cerebrovascular accident, subarachnoid
hemorrhage, or hypotha...
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