Chapter 003 Decision-Making in Clinical Medicine (Part 2) pdf

... Chapter 003. Decision-Making in Clinical Medicine (Part 2) The following three examples introduce the subject of clinical reasoning:  A 46-year-old man presents to his internist ... therefore more influential on clinical judgments. The third commonly used cognitive shortcut, the anchoring heuristic, involves estimating a probability by starting from a familiar poin...

Ngày tải lên: 06/07/2014, 08:20

... involved in Chapter 065. Gene Therapy in Clinical Medicine (Part 2) Figure 65-1 Indications in gene therapy clinical trials. The chart divides clinical gene transfer studies by disease ... single clone of T cells. In these children, the retroviral vector had integrated within a gene, LMO-2 (LIM only -2), which encodes a component of a transcription factor comp...

Ngày tải lên: 07/07/2014, 01:20

... documented in the pedigree include the presence or absence of nonhereditary risk factors among those affected with diseases, and the finding of multiple diseases in an individual patient. For instance, ... including grandparents. When pedigrees appear to suggest an inherited disease, they should be extended to include additional family members. The determination of risk for an asympto...

Ngày tải lên: 07/07/2014, 01:20

... heart has been viewed as a terminally differentiated organ without the capacity for Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 2) Strategies for Stem Cell ... considered (Fig. 67-1): (1) injection of stem cells directly into the damaged organ or into the circulation, allowing them to "home" into the damaged tissue; (2) in vitro...

Ngày tải lên: 07/07/2014, 01:20

... Prevention of urinary tract infections Kidney transplantation Nephrogenic XL, AR AVPR2, Fluid Chapter 064. The Practice of Genetics in Clinical Medicine (Part 7) Therapeutic Interventions ... Parkinson disease AD SNCA, PARK2 Amantadine, anticholinergics, levodopa, monoamine oxidase B inhibitors Wilson disease AR ATP7B Zinc, trientene Abbreviations: AD, autoso...

Ngày tải lên: 07/07/2014, 01:20

... Chapter 003. Decision-Making in Clinical Medicine (Part 1) Harrison's Internal Medicine > Chapter 3. Decision-Making in Clinical Medicine Decision-Making in Clinical Medicine: ... Uncertainty is compounded by the information overload that characterizes modern medicine. Today's experienced clinician needs close to 2 million pieces of inform...

Ngày tải lên: 06/07/2014, 08:20

... disease is the underlying cause. The absence of a resting Chapter 003. Decision-Making in Clinical Medicine (Part 3) Diagnostic Hypothesis Generation Cognitive scientists studying the thought ... make teaching diagnostic reasoning difficult is that expert clinicians do not follow a fixed pattern in patient examinations. From the outset, they are generating, refining, an...

Ngày tải lên: 06/07/2014, 08:20

... influence this role include the physician's knowledge, training, and experience. It is obvious that physicians cannot practice evidence-based medicine (EBM; described later in the chapter) if ... therapy in their heart failure patients because they are more familiar with what the targets are (as defined by large clinical trials), have more familiarity with the specific drugs...

Ngày tải lên: 06/07/2014, 08:20

... patients Chapter 003. Decision-Making in Clinical Medicine (Part 5) Economic Incentives Economic incentives are closely related to the other two categories of practice-modifying factors. Financial ... understanding of the patient's problem qualifies as a diagnostic test. Thus, even the history and physical examination can be considered a form of diagnostic test. In...

Ngày tải lên: 06/07/2014, 08:20

... predictive value is best avoided in favor of the more informative posttest probability. Chapter 003. Decision-Making in Clinical Medicine (Part 6) Calculating sensitivity and specificity ... response in a treadmill exercise test) to the exclusion of other potentially relevant data. In addition, ROC area comparisons do not simulate the way test information is actuall...

Ngày tải lên: 06/07/2014, 08:20