Pharmaceutical Substances Syntheses, Patents, Applications - Part 93 ppt

... BuLi. THF " + - aOH, H3C 0 CH- I tert-butyl acetometote tert-butyl (2 )-( E )-7 -[ 3-( 4-lluoro- phenyl). 1 -isopropylind0l- 2-~ l ]- 5-hydroxy-3-oxohept-6-enoate (VI) 1. CH,OB(C,H,), ... 2-( tributylstannyl)vinyl ethyl ether H3Cy~~3 THF, -7 8 OC ___, (E )-3 -[ 3-( 4-fluoro- phenyl )-1 -isopropyl- indol-2-yl ]- propenal (11) me...

Ngày tải lên: 02/07/2014, 02:20

... Hakko) Aspartame LJse: sweetener (pharmaceutical agent) RN: 2283 9-4 7-0 MF: C,,H,,N,O, MW: 294.31 EINECS: 24 5-2 6 1-3 CN: N-L-a-aspartyl-L-phenylalanine 1-methyl ester L-osportic L-aspartic ... antiarrhythmic RN: 3764 0-7 1-4 MF: CI2,H3,N, MW: 322.50 LD,,: 274 mgkg (M, p.0.) CN: N-(2,3-dihydro-lH-inden-2-yl)-RP,N-diethyl-N-phenyl-l,3-propanediamine monohydrochlo...

Ngày tải lên: 02/07/2014, 02:20

... RN: 201 6-6 3-9 MF: C,,H,,N,O, MW: 385.47 CN: 7-[ 2-[ ethyl(2-hydroxyethyl)aminolethyl ]-3 ,7-dihydro-1,3-dimethyl- 8-( phenylmethyl )-1 H-purine-2,6~ dione monohydrochloride RN: 2068 4-0 6-4 MF: ... penicillin) RN: 5097 2-1 7-3 MF: CzIHz7N,07S MW: 465.53 CN: [2S-[2a,5a,6~(S*)] ]-6 -[ (aminophenylacetyl)a~no ]-3 , 3-~ methyl-7-oxo-4-thia-l- azabicy...

Ngày tải lên: 02/07/2014, 02:20

... 469 6-7 6-8 MF: C,8H,7N,01, MW: 483.52 EINECS: 22 5-1 7 0-5 LD,,: 136 rnglkg (M, i.v.) CN: 0-3 -amino-3-deoxy-cx-~-glucopyranosyl-(l+6 )-0 -[ 2,6-diamino-2,6-dideoxy-a-~-glucopyranosyl- (I +4) ]-2 -deoxy-D-streptamine ... ethyl 11 3-chloro-2.3.4.5-te- trohydro-1H-1 -benz- ozepin-2-one (I) 3-ozido-2.3.4.5-te- bromoacetote trohydro-1 H-l-benz- ozepin-2-one 0 1. Hz...

Ngày tải lên: 02/07/2014, 02:20

... 559 3-2 0-4 MF: C2,H,,FO7 MW: 504.60 EINECS: 22 7-0 0 5-2 LDso: >5 glkg (M, p.0.); >4 gkg (R, pa.) CN: (1 IP,16P )-9 -fluoro-l l-hydroxy-16-methyl-l7,21-bis(l-oxopropoxy)pregna-l,4-diene-3,20-dione ... glucocorticoid RN: 36 0-6 3-4 MF: CZ2H,FO8P MW: 472.45 EINECS: 20 6-6 3 6-7 LD,,: 700 mglkg (M, i.p.) CN: (1 1 P, 16~ )-9 -fluoro-l1,17-dihydroxy-l6-methyl-...

Ngày tải lên: 02/07/2014, 02:20

... (synthetic) RN: 47 9-6 8-5 MF: CzzHI,Br MW: 363.30 EINECS: 20 7-5 3 7-1 CN: 1-( 2-bromo-l,2-diphenylethenyl )-4 -ethylbenzene I-ethyl-4-phenyl- phenylmognesium 1.2-diphenyl- 1-( 4- Broporestrol ocetylbenzene ... acetonitrile 1 -3 -dithiane ester 2-omino- 3-( 2- chlorobenzoyl )- thiophene 1. Br2, pyridine 1. bromine HN 2. phosphorus 5-( 2-chl0rop...

Ngày tải lên: 02/07/2014, 02:20

... [5a,7a(S) ]-1 7-( cyclopropylmethyl)-a-(l,l-dimethylethyl )-4 ,5-epoxy-18,19-dihydr 0-3 -hydroxy- 6- rnethoxy-a-methyl-6,14-ethenomorphinan-7-methanol hydrochloride RN: 5315 2-2 1-9 MF: C2,H4,N04 . HCI MW: 504.1 1 EINECS: 25 8-3 9 6-8 thebaine 7a-acetyl-6,14-endo- ... cyclopropone- 1. brornocyan carbonyl chloride CHs 6.14-endo-ethano-7a- [(IS )-1 -hydroxy...

Ngày tải lên: 02/07/2014, 02:20

... 7-chloro-2,3-dihydro-l-methyl-2-oxo-5-phenyl-1H-l,4-benzodiazepin-3-y1 ester 6-chloro-2-chloro- 7-chloro-5-phenyl- methyl-4-phenyl- 1.3-dihydro-2H-1. 4- quinazoline 3-oxide benzodiazepin-2-one (cf. chlordiozepoxide 4-oxide synthesis) ... 316.49 CN: (7~,17~ )-1 7-hydroxy-7,17-dimethylandrost-4-en-3-one J,7.17,7-diocetoxy-17a-methyl- methyl- 7-0 x 0-5 -ondrostene lithium...

Ngày tải lên: 02/07/2014, 02:20

... RN: 6 9-8 1-8 MF: CloHI,N4O3 MW: 236.23 EINECS: 20 0-7 1 7-0 LD,,,: >35.832 glkg (M, p.0.); >17.280 glkg (R, p.0.) CN: 2-( 1,2,3,6-tetrahydro-3-hydroxy-1-methyl-6-oxo-5H-indol-5-ylidene)hydrazinecarb0xamide ... 3-acetylthio-2-methyl- (11) acid (I) acid propionic ocid L-proline (Ill) benzyl U N-benzyloxycorbonyl- chloroformote L-proline N-benzyloxycarbonyl-L...

Ngày tải lên: 02/07/2014, 02:20

... methyl- potassium N-omino- hydrozine rhodanide N-melhyl- thiourea 7-orninocephalo- sporonic ocid 7(R)-omino- 3-[ [(2,5-dihydro- 6-hydroxy-2-methyl-50x 0- 1,2,4-triazin-3-yl)thio]methyl ]- 3-cephem-4-corboxylic ... [6R-[6a,7~(Z)J ]-7 -[ [(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-X-oxo- 3-[ [(1,2,5,6-tetrahydro- 2- methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]met...

Ngày tải lên: 02/07/2014, 02:20