Pharmaceutical Substances Syntheses, Patents, Applications - Part 53 ppt
Pharmaceutical Substances Syntheses, Patents, Applications - Part 53 ppt
... anticonvulsant
RN: 162 2-6 1-3 MF: C15HloC1N,03 MW: 3 15.72 EINECS: 21 6-5 9 6-2
CN: 5-( 2-chloropheny1 )- 1,3-dihydro-7-nitro-2H- l,4-benzodiazepin-2-one
H
Hz,
Raney-Ni
":-Ic,
'XBr
%rBr ...
\
2-chloro-2&apos ;- 2-amino-2&apos ;-
(1)
n~trobenzo- chlorobenzo-
phenone phenone
liq
NH3
NVNH~
pyridine
KNOJ, H2S0,
I
F
___*
-N
+
/
\
Cl
\
-...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 14 pptx
... Hakko)
Aspartame
LJse: sweetener (pharmaceutical agent)
RN: 2283 9-4 7-0
MF:
C,,H,,N,O, MW: 294.31 EINECS: 24 5-2 6 1-3
CN:
N-L-a-aspartyl-L-phenylalanine
1-methyl ester
L-osportic L-aspartic ... antiarrhythmic
RN: 3764 0-7 1-4 MF: CI2,H3,N, MW: 322.50
LD,,: 274 mgkg
(M,
p.0.)
CN:
N-(2,3-dihydro-lH-inden-2-yl)-RP,N-diethyl-N-phenyl-l,3-propanediamine
monohydrochlo...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 18 ppt
... penicillin)
RN: 5097 2-1 7-3 MF: CzIHz7N,07S MW: 465 .53
CN:
[2S-[2a,5a,6~(S*)] ]-6 -[ (aminophenylacetyl)a~no ]-3 , 3-~ methyl-7-oxo-4-thia-l-
azabicyclo[3.2.0]heptane-2-carboxylic
acid 1
-[ (ethoxycarbonyl)oxy]ethyl ...
RN:
201 6-6 3-9
MF: C,,H,,N,O,
MW:
385.47
CN:
7-[ 2-[ ethyl(2-hydroxyethyl)aminolethyl ]-3 ,7-dihydro-1,3-dimethyl- 8-( phenylmethyl...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 19 pptx
... 469 6-7 6-8 MF: C,8H,7N,01, MW: 483.52 EINECS: 22 5-1 7 0-5
LD,,: 136 rnglkg (M, i.v.)
CN:
0-3 -amino-3-deoxy-cx-~-glucopyranosyl-(l+6 )-0 -[ 2,6-diamino-2,6-dideoxy-a-~-glucopyranosyl-
(I
+4) ]-2 -deoxy-D-streptamine ...
ethyl 11
3-chloro-2.3.4.5-te-
trohydro-1H-1 -benz-
ozepin-2-one (I)
3-ozido-2.3.4.5-te- bromoacetote
trohydro-1 H-l-benz-
ozepin-2-one
0
1.
Hz...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 24 ppt
... glucocorticoid
RN: 381 9 6-4 4-0 MF: C3,H4,F0, MW: 560.70 EINECS: 25 3-8 2 0-8
CN: (1 1
P,
16P )-9 -fluoro-l l-hydroxy-
16-methyl-17,21-bis[(1-oxopentyl)oxy]pregna-l,4-diene-3,20-dione
pyridine
betamethasane ... 559 3-2 0-4 MF: C2,H,,FO7 MW: 504.60 EINECS: 22 7-0 0 5-2
LDso: >5 glkg (M, p.0.);
>4 gkg (R, pa.)
CN: (1 IP,16P )-9 -fluoro-l
l-hydroxy-16-methyl...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 28 ppt
... phosphorus
5-( 2-chl0rophenyl )- pentosulfide 7-brom 0-5 -( 2-
1,3-dihydro-2H-thieno- chloropheny1 )- 1. 3-
[2,3-el-1.4-diozepin-
2-one
(I)
278
B
Buclizine
bucladesine
RN: 36 2-7 4-3 MF: C,xH,N,OxP ... (synthetic)
RN: 47 9-6 8-5 MF:
CzzHI,Br MW: 363.30 EINECS: 20 7-5 3 7-1
CN:
1-( 2-bromo-l,2-diphenylethenyl )-4 -ethylbenzene
I-ethyl-4-phenyl-...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 30 ppt
...
[5a,7a(S) ]-1 7-( cyclopropylmethyl)-a-(l,l-dimethylethyl )-4 ,5-epoxy-18,19-dihydr 0-3 -hydroxy- 6-
rnethoxy-a-methyl-6,14-ethenomorphinan-7-methanol
hydrochloride
RN:
531 5 2-2 1-9 MF: C2,H4,N04
.
HCI MW: 504.1
1
EINECS: 25 8-3 9 6-8
thebaine
7a-acetyl-6,14-endo- ...
cyclopropone-
1. brornocyan
carbonyl chloride
CHs
6.14-endo-ethano-7a-
[(IS )-1 -hydrox...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 33 ppt
...
7-chloro-2,3-dihydro-l-methyl-2-oxo-5-phenyl-1H-l,4-benzodiazepin-3-y1
ester
6-chloro-2-chloro- 7-chloro-5-phenyl-
methyl-4-phenyl- 1.3-dihydro-2H-1. 4-
quinazoline 3-oxide benzodiazepin-2-one
(cf. chlordiozepoxide 4-oxide
synthesis) ... 316.49
CN:
(7~,17~ )-1 7-hydroxy-7,17-dimethylandrost-4-en-3-one
J,7.17,7-diocetoxy-17a-methyl-
methyl-
7-0 x 0-5 -ondrostene lithium...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 34 ppt
... 3-acetylthio-2-methyl-
(11)
acid
(I)
acid propionic ocid
L-proline
(Ill)
benzyl
U
N-benzyloxycorbonyl-
chloroformote L-proline
N-benzyloxycarbonyl-L- L-proline tert-
proline tert-butyl ...
N-Carbamoyl-L-aspartic acid calcium salt
Use: psychoenergetic, tranquilizer
(Calcii
carbaspartas)
RN: 1664 9-7 9-9 MF: C5H,CaN,0, MW: 214.19 EINECS: 24 0-6 9 8-6
CN:
N-(aminocarbo...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 41 ppt
...
methyl-
potassium N-omino-
hydrozine
rhodanide N-melhyl-
thiourea
7-orninocephalo-
sporonic ocid
7(R)-omino- 3-[ [(2,5-dihydro-
6-hydroxy-2-methyl-50x 0-
1,2,4-triazin-3-yl)thio]methyl ]-
3-cephem-4-corboxylic ...
[6R-[6a,7~(Z)J ]-7 -[ [(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-X-oxo- 3-[ [(1,2,5,6-tetrahydro- 2-
methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]met...