Pharmaceutical Substances Syntheses, Patents, Applications - Part 9 pot
Pharmaceutical Substances Syntheses, Patents, Applications - Part 1 pot
...
transcriptase inhibitor
I
RN: 13 647 0-7 8-5 MF: C,4H,uN60 MW: 286.34
1
CN:
(1S,4R )-4 -[ 2-Amino- 6-( cyclopropylamino )-9 H-purin-9-yl ]-2 -cyclopentene-l-methanol
succinate
RN: 16 814 6-8 4-7 MF: Cl,HluN,O
. ... 23.7 .19 91; appl. 22 .12 .19 89; GB-prior. 27.6 .19 88).
d
WO 9 924 4 31 (Glaxo; appl. 12 .1 1 .19 98; WO-prior. 12 .1 1 .19 97).
alternative...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 2 potx
... levulinoyloxyacetate
benzyl 1 2- ( 4-methoxyphenylhydrozano )-
'=?'
benzyl
(5-meVloxy -2 - methyl-3-lndolyl-
4-chloro-
benzoyl chloride
benzyl
[I
-( 4-chlorobenzoyl )-5 -methoxy-
2- methyl-3-indolylocetoxy]acetate ... C,yH22N20S MW: 326 .46 EINECS: 23 6-6 6 1-9
LD,,: 517 mgkg (M, p.0.)
CN:
1-[ l 0-[ 2- ( dimethylamino)propyl ]-1 0H-phenothiazin -2...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 8 potx
... 5 58 8- 1 6-9 MF: C,,H14C1N304S3
MW:
383 .90 EINECS: 22 6-9 9 4 -8
CN:
6-chloro-3,4-dihydro- 3-[ (2-propenylthio)methy1 ]-2 H-
1,2,4-benzothiadiazine-7-sulfonamide
1,
l-dioxide
6-amino-4-chloro- chloroocetaldehyde ... hydrochloride
CH3-CO-NH-NH2
,
butanol
-
acetohydrazide
2-0 x 0-2 .3-dihydro-lH-
2-thioxo-2,3-dihydro- 7-chloro-5-phenyl-3H-
1.4-benzodiazepin...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 9 pot
... 3751 7-2 8-5 MF: C22H43NJ013 MW: 585.61 EINECS: 25 3-5 3 8-5
LD5,:
280 mgkg (M, i.v.); >6 glkg (M, p.0.)
CN:
(S)-O-3-amino-3-deoxy- ~-~ -glucopyranosyl-(1+6 )-0 -[ 6-amino-6-deoxy-a-u-glucopyranosyl-(l~4) ]- ... 298 499 (Res. Triangle Inst.; appl. 5.7. 199 1; USA-prior. 5.7. 199 1).
WO 8 90 7 94 2 (US Bioscience; appl. 21.2. 198 9; USA-prior. 23.2. 198 8).
US 5 167...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 13 potx
...
1-cyclohexyl-3-morpholinyl-
ethyl-corbodiimide
+
N
b
VII
H-Val-Tyr-Val-His-Pro-Phe-0-CH
(VI)
I-N
ti2,
~d-C.CH~OH
-m
H H
Z-Asn-Arg(N02)-Val-Tyr-Val-His-Pro-Phe-0-CH
(W)
130
A
Apalcillin ...
Z-N
0
111
+
HN,COOH
\INYN/~0,
H
H
Z
-Asn-Arg(N0,)-OH
(N)
DMF,
1
-cyclahexyl- 3-
morpholinylethyl-carbodiimide
+
I1
v
Z-Val-Tyr-Val-His-Pro-Phe-0-CH
(V)
DMF,
1-cyc...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 22 potx
...
1,2,3.4-tetrahydro-6,7-dimethoxy-
2-isoquinolineprapionote
[Ill)
ethyl 1.3.4.6.7.1 1 b-hexohydm-
N.N-diethyl-1.3.4.6.7,ll
b-hexahydro-9.10.
dimethoxy- 2-0 x 0-2 H-
9,lO-dimethaxy- 2-0 x 0-2 H-
benzo[o]quinalizine- ...
6-chloro- 3-[ [(phenylmethyl)thio]methyl ]-2 H-1,2,4-benzothiadiazine-7-sulfonamide
1,l-dioxide
5-chloro-2.4-diomino- chloro-
7-ominonulfonyl-6-chloro-...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 23 pot
... 98 7-2 4-6 MF: C,H3,F06 MW: 434.50 EINECS: 21 3-5 7 8-6
CN: (1 1
~,16~ )-2 1-( acetyloxy )-9 -fluoro-l1,17-dihydroxy-16-methylpregna-l,4-diene-3,20-dione
1.
CH3-SO2-CI,
pyridine
0
2.
CH3-CO-NH-Br, ... anti-inflammatory, steroidal
(BBP;
TO-
I
86)
agent
RN: 553 4-0 2-1 MF: C,,H,,F07 MW: 518.62
CN:
(1 1 P, 16P )-9 -fluoro-1 I-hydroxy- 16-methyl- 1 7-( 1
-ox...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 25 potx
...
RN:
3463 3-3 4-6 MF: C,,H,,F,O, MW: 292.33
CN:
(R*,S* )-4 ,4&apos ;-( 1-ethyl-2-methyl-l,2-ethanediyl)bis[2-fluorophenol]
3-chloro- 2-
trans-2.3-bis(3-fluora-4-methoxy-
pentanone phenyl )-2 -pentene ... 20 0-3 9 9-3
CN:
[3aS-(3aa,4~,6aa)]-hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic
acid
fumoric ocid mesa-2.3-dibromo- cis-1,3-dibenzyl-
succinic ocid 2-axo...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 26 pot
... (? )-3 .4-dihydro- 4-
hydroxy-2H-thieno-
[3,2-el-1,2-thiozine
1
,l
-dioxide
(111)
hydride
OH
1,3-dibromo- (? )-2 -( 3-bromopropyl )-
propone
3,4-dihydro-4-hydroxy-
2H-thieno[3.2-el-1. 2-
thiozine ... 1310 3-3 4-9 MF: C,,HN03
MW:
452.68 EINECS: 23 6-0 2 4-5
CN:
(17~ )-1 7-[ (I-oxo-l0-undecenyl)oxy]androsta-l,4-dien-3-one
boldenone
RN: 84 6-4 8-0...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 27 potx
... ocetate. O°C
XI1
-
XI11
3-( brornoocetyl )-
5-chloro- 2-
thiophenesulfonomide
(XlIl)
K2C03, DMSO
XN
+
X
b
4-hydroxy- 2-( 3-rnethoxy-
propy1 )-2 H- thieno[3.2-el-
1,2-thiozine 1.1-dioxide (XV) ... oxolate
Z-picaline 2-picoline ethyl 2-pyridyl-
1
-axide pyruvate 1'-oxide
(In)
4-brornophenyl-
hydrozine hydrochloride
ethyl 5-brorno- 3-
(2-pyridy1)ind...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 42 potx
... 143 1 .O6
CN:
N-Acetyl- 3-( 2-naphthalenyl )-~ -alanyl-4-choro-~-phenyaanyl- 3-( 3-pyridinyl )-~ -alanyl-~-seryl- ~-
tyrosyl- ~-( aminocarbonyl )-~ -ornithyl-~-leucyl-~-arginy ~-~ -prolyl-~-alaninamide
... 1765 0-9 8-5 MF:
C5RH73N1302LS2
MW: 1352 .42
LD,,:
1012 mgkg
(M,
i.v.)
CN:
5-oxo-~-prolyl-~-glutaminyl-~-a-asparty-O-sulfo-~-tyrosyl-~-threonylglycyl-~-tr...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 46 potx
... bronchodilator
RN: 449 9-4 0-5 MF: C7H7N402. C5H,,N0 MW: 283.33 EINECS: 22 4-7 9 8-7
CN:
2-hydroxy-N,N,N-trimethylethanaminium,
salt with
3,7-dihydro-l,3-dimethyl-IH-purine-2,6-dione
(1:l)
a-Chymotrypsin ...
CN:
(2R-trans )-2 -( 3,4-dihydroxyphenyl )-3 ,4-dihydro-2H-I-benzopyran-3,5,7-triol
Cholestyramine
C
453
Formulation(s):
tabl. 250 mg, 500 mg
Trade Name(s):
D...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 47 potx
... 5986 5-1 3-3 MF: C,,Hll,N,,O,, MW: 1202.64
CN:
[R-[R*,S *-( E)]]-cyclic(~-alanyl-~-alanyl-N-methyl-~-leucyl-N-methyl-~-leucyl-N-methyl-~-valyl- 3-
hydroxy-N,4-dimethyl- ~-2 -amino-6-octenoyl-~-a-aminobutyryl-N-methylglycyl-N-methyl-~-leucyl- ~- ...
hydrochloride
methyl 5-cyclohexyl-
3-methyl- 5-0 x 0-2 -
pentenoote (mixture
with
the 3-pentenoote:
from methyl 4-me...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 48 pot
...
RN: 2388 7-4 6-9 MF:
Cz2H,,N3Os MW: 417.51 EINECS: 24 5-9 2 8-9
CN:
1-[ 2-oxo- 2-( l-pyrrolidinyl)ethyl ]-4 -[ l-oxo- 3-( 3,4,5-trimethoxyphcnyl)2-propenyl]pipera~ine
maleate
(1:l)
RN: 2632 8-0 4-1 MF: ...
7569 6-0 2-5
MF:
C,,H,,ClFN,O,
MW:
357.77
LD,,,:
3.5 glkg (R, p.0.)
3.5 glkg (M, p.o)
CN:
(+ )-7 -Chloro- 5-( 2-fluorophenyl )-2 ,3-dihydro-...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 56 potx
...
l 0-[ 3-( dimethylamino )-2 -methylpropyl ]-1 0H-phenothiazine-2-carbonitrile
Z-chloropheno-
thiozine
P-cyanopheno-
thiozine
1.
NaNH2, xylene
2.
cl&i:3
CH3
I
2.
1
-chloro-3-dimethyl-
amino-2-methyl-
Cyamemazine ... tonic
RN: 63 3-4 7-6 MF: C,3H24N202
MW:
240.35 EINECS: 2
1
1-1 9 3-8
CN:
N-[ 1-[ (dirnethylamino)carbonyI]propyl]-N-propyl-2-butenamid...