Pharmaceutical Substances Syntheses, Patents, Applications - Part 6 doc

... 551 1-9 8-8 MF: C 431 1hh015 MW: 822.99 EINECS: 22 6-8 5 5-1 LD,,,: 33 00 vg/kg(g. p., p.0.); 200 vg/kg (cat, p.0.) CN: (3~ ,5~,12~ ) -3 -[ ( 0 -3 -0 -acetyl-2,6-dideoxy- ~-~ -ribo-hexopyranosy-(+4 )-0 -2 ,6-dideoxy- ~-~ -ribo- ... (dog, p.o.1 CN: (3~ ,5~,12~ ) -3 -[ ( 0-4 -0 -acetyl-2,6-dideoxy-[oxy- ~-~ -ribo- hexopyranosyl-(l~4 )-2 ,6-dideoxy- ~-~...

Ngày tải lên: 02/07/2014, 02:20

... 2435 6- 9 4-3 MF: C2,H3,04 MW: 448 .60 EINECS: 24 6- 1 9 5-8 CN: [16a(R) ]-1 6, 1 7-[ (l-phenylethylidene)bis(oxy)]pregn-4-ene-3,2O-dione dgestone RN: 59 5-7 7-7 MF: C2,H3,0, MW: 3 46. 47 EINECS: 20 9-8 6 9-2 ... analgesic, short-time anesthetic (for basal narcosis) RN: 7119 5-5 8-9 MF: C2,H32N,03 MW: 4 16. 53 CN: N-[ 1-[ 2-( 4-ethyl-4,5-dihydro-5-oxo-1H-...

Ngày tải lên: 02/07/2014, 02:20

... o,-agonist RN: 8262 6-0 1 -5 MF: C2,Hz3CI2N3O MW: 404.34 CN: 6-chloro- 2-( 4-chlorophenyl)-N,~propylimidazo[l,2-a]pyridine-3-acetamide 2-omino- 5- 4'-chloro-2-brorno- 6-chloro- 2-( 4-chloro- ... ATC: R07AB 07 Use: analeptic, respiratory stimulant RN: 274 6 9-5 3-0 MF: C,,H,,F,N, MW: 477 .56 EINECS: 24 8-4 7 5-5 CN: 6-[ 4-[ bis(4-fluorophenyl)methy...

Ngày tải lên: 02/07/2014, 02:20

... [2S-(2a,5a,6~)]-N-methyl-~-asparaginyl-N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia- 1 - azabicyclo[3.2.0]hept-6-yl)-D- 2-( 4-hydroxyphenyl)glycinamide 0 NH, Nps-CI . K2CD3. pH 8 HN/N~s o-nitrophenyl- ... CN: l-[(4-fluorophenyl)methyl]-N-[I-[ 2-( 4-methoxyphenyl)dhyl ]-4 -piperidinyl ]-1 H-benzimidazol-2-amine H2N ~o~cH3 ethyl 4-ornino- piperidine-1 -carboxylaie 2-nit...

Ngày tải lên: 02/07/2014, 02:20

... S-[ 2-[ [(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino ]- 1-[ 2- (benzoyloxy)ethyl ]-1 -propenyl] ester thiamine N-(4-amino-2-methylpyrimidin- (q v.) 5-ylrnethy1)-N-(4-hydroxy- 1- methyl-2-mercaptobutl-enyl )- forrnarnide (1) 208 B Benziodarone ... Benzathine) RN: 153 8-0 9-6 MF: C,6H,,N204S . 1/2Cl6HzON, MW: 909.14 EINECS: 21 6-2 6 0-5 LD...

Ngày tải lên: 02/07/2014, 02:20

... EINECS: 22 0-0 7 2-9 CN: 1-[ 1 0-[ 3-[ 4-( 2-hydroxyethyl)-l-piperazinyl]propy1 ]-1 OH-phenothiazin-2-yl]-I-propanone dimaleate RN: 297 5-3 4-0 MF: C2,H3,N302S 2C4H404 MW: 657.74 EINECS: 22 1-0 1 9-2 LD,,: ... 2702 5-4 9-6 MF: C23H22N206S MW: 454.50 EINECS: 24 8-1 7 1-2 LD,,: 728 mg/kg (M, i.v.); 3924 mglkg (M, p.0.) CN: [2S-(2a,5a,6~) 1-6 -[ (1,3-...

Ngày tải lên: 02/07/2014, 02:20

... [6R-[6a,7~(R*)] ]-7 -[ [amino(4-hydroxyphenyl)acetyl]amino ]-3 -methyl-8-oxo-5-thia-l- azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 2. 7-amino-3-deacetoxy- cepholosporonic acid D (-) -4 -hydroxy-N-(2-meth- oxycorbonyl- 1 -methyl- etheny1)phenylglycine ... II R' H R' H 4-nitrobenzyl 4-nitrobenzyl 3- 3-methylane- 7-( 2- hydroxy- 7-( 2-thienyl thien...

Ngày tải lên: 02/07/2014, 02:20

... [6R-(6a,7a) ]-7 -[ [[ 4-( 2-amino-l-carboxy-2-oxoethylidene)-l,3-dithietan-2-yl]carbonyl]amino ]-7 - methoxy- 3-[ [(1 -methyl- lH-tetrazol-5-yl)thio]rnethyl ]-8 -oxo-5-thia-l -azabicyclo[4.2.0]oct-2-ene- 2- carboxylic ... 51 1.57 CN: , [6R-[6a,7~(Z)l ]-7 -[ [(2-amino-4-thiazolyl)(methoxyiminv)cetyl]amino ]-3 -[ [(l-methyl-1H-tetrazol- 5- yl)thiolmethyl ]-8...

Ngày tải lên: 02/07/2014, 02:20

... 2-( 4-chlorophenyl)tetrahydro-3-methyl-4H-l,3-thiazin-4-one 1, I-dioxide 3-mercapto- methyl- 4-chloro- 2-( 4-chloropheny1 )- propionic amine benzoldehyde 3-methyltetm- acid hydro- 1.3-thiozin- 4-one Rejierence(s): GB ... antihistaminic RN: 14 8-6 5-2 MF: C,,H,,ClN,S MW: 295.84 LD,,,: 105 mg/kg (M, i.p.) CN: N-[(5-chloro-2-thienyl)methyl]-A~,h~-dimethyl-N-2-pydinyl-1,2...

Ngày tải lên: 02/07/2014, 02:20

... (NSC- 1 0501 4-F; RWJ-2625 1 ; 2-CdA) RN: 429 1-6 3-8 MF: C,,H,,CIN,O, MW: 285.69 CN: 2-chloro-2'-deoxyadenosine ATC: LOlBB04 Use: antineoplastic CH, 2.6-dichloro- 2-deoxy-3.5-di-O-p- ... HN CH3 K 0 methyl 2-methoxy- 4-aceiamido- 5- chlorobenzoate (I) COOH 2-methoxy- 4- amino-5-chloro- benzaic acid (11) 2. 111 NH2 Clebopride 1-benzyl-4-amino- piper...

Ngày tải lên: 02/07/2014, 02:20

... MW: 435.89 EINECS: 20 0-5 1 4-7 CN: [2S-(2a,5a,6~) ~-6 -[ [[ 3-( 2-chlorophenyl )-5 -methyl-4-isoxazolyl]carbonyl]amino ]-3 ,3-dimethyl-7-oxo- 4- thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid monosodium ... EINECS: 20 5-8 3 6-1 LD,,,: >I g/kg (M, i.m.); >500 mglkg (R, i.m.) CN: 3-[ (4-amino-2-methyl-5-pyrimidinyl)methy1 ]-4 -methyl- 5-( 4,6,6-trih...

Ngày tải lên: 02/07/2014, 02:20

... 3449 3-9 8-6 MF: C18H3,N508 MW: 451.52 EINECS: 25 2-0 6 4-6 LD,,: 37 3-3 80 mgkg (M, i.p.); 6 1-6 8 mdkg (M, i.v.) CN: 0-3 -amino-3-deoxy-a-~-g~ucopyranosy ~-( l+6 )-0 -[ 2,6-diamino-~,3,4,6-tetradeoxy-a-~-erythro- ... Use: tranquilizer, hypnotic RN: 43 9-1 4-5 MF: C,,H,,ClN,O MW: 284.75 EINECS: 20 7-1 2 2-5 CN: 7-chloro-1,3-dihydro-l-methyl-5-phenyl-2H-l...

Ngày tải lên: 02/07/2014, 02:20

... (3~,5~,12~ )-3 -[ ( 0-2 ,6-dideoxy- ~-~ -ribo-hexopyranosy 1-( 1~4 )-0 -2 ,6-dideox ~-~ -~ -ribo-hexo~~ranos~l- (14 )-2 ,6-dideoxy- ~-~ -ribo-hexopyranosyl)oxy ]-1 2,14-dihydroxycard-20(22)-enolide @ from Digitalis lonata ... 24 1-4 9 3-4 CN: (5'a,lOa )-9 ,I0-dihydro-l2'-hydroxy-2&apos ;-( l-methylethyl )-5 &apos ;-( phenylmethyl)crgotaman-3&...

Ngày tải lên: 02/07/2014, 02:20

... antihistaminic RN: 247 0-7 3-7 MF: C24H33N302S MW: 427.61 EINECS: 21 9-5 9 1-3 LDS,,: 37.5 mg/kg (R, i.v.); 400 mg/kg (R, p.0.) CN: 2-[ 2-[ 4-[ 2-methyl- 3-( 1OH-phenothiazin-1O-yl)-propyl ]-1 -piperazinyl]ethoxy]ethanol ... 12b-(acetyloxy )-1 2-( benzoyloxy )-2 a,3,4,4a,5,6,9,10,11,12,12a ,-1 2b- dodecahydro-4,6,1l-trihydroxy-4a,8,13,13-tetramethyl-5-o...

Ngày tải lên: 02/07/2014, 02:20

... I - Docetoxel , I CH3 3-ocetoxy-4-phenyl- 1- [(S )-1 -phenylethyll- 2- ' ozetidinone (XV) (? )-1 -phenyl- 1- (tert-butoxycorbonyl- amino )-2 -hydroxy- 3-butene (XVII) P Docetaxel ... _____* ethyl (2RJS )-2 -hydroxy- 3-[ (S )-1 -phenylethylamino ]- 3-phenylpropionate ethyl (2R.X )-3 -omino- 2-hydroxy-3-phenyl- propionate (XVI)...

Ngày tải lên: 02/07/2014, 02:20