... glucoamylaseactivity, 20% of the maltase activity, and 1% of the sucrase activity [10]. Together, these two enzymes forma complex in the epithelial cells of the small intestineand complete the hydrolysis of oligosaccharide ... generated in the intestinal scrapings by a-amylase present in the hetero-geneous sample or by activity in the C-terminaldomain of the full-size protein, thereby accounting for the inhibition by ‘acarbose’ ... candi-dates for the treatment of Type 2 diabetes [23]. Inorder to examine the mechanism of action of thisclass of inhibitors, 3, 5, the stereoisomers of salacinol6, 7 [25], and the six-membered...