MOLECULAR REGULATION OF ENDOCYTOSIS pot
... Molecular Regulation of Endocytosis 12 9. Possible implications of synaptic vesicle endocytosis for disease mechanisms Knowledge about the mechanisms of synaptic vesicle endocytosis ... distribution of Vid24p by immunofluorescence microscopy. In contrast, Vid24p produced a stronger Molecular Regulation of Endocytosis 34 Figure 9. Current model of the Vid...
Ngày tải lên: 28/06/2014, 15:20
... reactions could potentially be part of a Molecular Regulation of Endocytosis 42 help of electron tomography, we have been able to quantify the distribution of vesicles in the cell cortex. ... heavy chain, Molecular Regulation of Endocytosis 48 fluorescent dot may in some instances correspond to a cluster of several clathrin-coated pits and vesicles (Fig....
Ngày tải lên: 24/03/2014, 02:21
... None of these mutations was detected through direct sequencing of lesion DNA, emphasizing the lack of sensitivity of direct sequencing of lesion DNA. These data established the existence of biallelic somatic ... future The recent identification of the three CCM genes is an important step towards the elucidation of the mecha- nisms of this condition. It helped to clarify sever...
Ngày tải lên: 15/03/2014, 10:20
Báo cáo khoa học: MicroRNAs and the regulation of fibrosis potx
... development of diabetic nephropathy through the down -regulation of PTEN and the subsequent acti- vation of Akt (Fig. 1) [43]. Increased expression of miR-377 is also thought to regulate the expression of fibronectin, ... ARTICLE MicroRNAs and the regulation of fibrosis Xiaoying Jiang 1,2 , Eleni Tsitsiou 2 , Sarah E. Herrick 2 and Mark A. Lindsay 2 1 Department of Genetics and...
Ngày tải lên: 15/03/2014, 11:20
Tài liệu Báo cáo Y học: Presence and regulation of the endocannabinoid system in human dendritic cells potx
... representative of all the samples analyzed, as in only three preparations out of the six analyzed was a decrease of mRNA transcripts observed. Fig. 3. Western immunoblotting of protein homogenates of human immature ... amounts of CB 1 and CB 2 receptors and of FAAH. Cell maturation did not consistently modify the expression of these pro- teins, although in some cell preparatio...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo khoa học: Molecular basis of perinatal hypophosphatasia with tissue-nonspecific alkaline phosphatase bearing a conservative replacement of valine by alanine at position 406 Structural importance of the crown domain potx
... conformation of the crown domain, which is presumably indispensable for the efficient catalytic function of TNSALP. In support of our hypothesis, the cysteine residue at position 433 in one subunit of TNSALP ... Left lane: 14 C-methylated protein markers of 200, 97.5, 66, 46 and 30 kDa, from the top of the gel. N. Numa et al. Molecular basis of perinatal form of hypophosphata...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Iron regulatory protein-independent regulation of ferritin synthesis by nitrogen monoxide pot
... Arosio P (1988) Mechanism of fer- ritin iron uptake: activity of the H-chain and deletion mapping of the ferro-oxidase site. A study of iron uptake and ferro-oxidase activity of human liver, recom- binant ... (2004) Balancing acts: molecular control of mammalian iron metabolism. Cell 117, 285–297. 13 Richardson DR & Ponka P (1997) The molecular mechanisms of the metaboli...
Ngày tải lên: 07/03/2014, 12:20
REGULATION OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL on the Cohesion Fund and repealing Council Regulation (EC) No 1084/2006 pot
... *All figures in constant 2011 prices 5. SUMMARY OF CONTENT OF THE PROPOSED REGULATION The proposed Regulation determines the scope of intervention of the Cohesion Fund. It includes an article ... This Regulation replaces Council Regulation (EC) No 1084/2006 of 11 July 2006 establishing the Cohesion Fund and repealing Regulation (EC) No 1164/94 12 . In the interest o...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: Diverging regulation of pyruvate dehydrogenase kinase isoform gene expression in cultured human muscle cells pot
... electrophoresis (data not shown). Molecular cloning of each PDK or PDP isoform was confirmed by sequence comparison of each clone with E. L. Abbot et al. Regulation of hPDK2 and hPDK4 gene expression FEBS ... dehydrogenase phosphatase (PDP). To date, four isoforms of PDK (PDK1–4) and two isoforms of PDP (PDP1–2) have been identified in humans [3–5]. These isoforms display unique t...
Ngày tải lên: 07/03/2014, 17:20
Báo cáo khoa học: Regulation of arginase II by interferon regulatory factor 3 and the involvement of polyamines in the antiviral response potx
... in the regulation of apop- tosis [21,22]. Thus, the possibility that the antiviral effect of spermine is mediated by induction of apop- tosis was analyzed. For this purpose, the effect of spermine ... MG-132 [20], suggesting indirectly an involvement of NF-jBin ArgII regulation. Our study is thus the first direct demonstration of the involvement of IRF-3 in ArgII regulation...
Ngày tải lên: 07/03/2014, 21:20