... move away from the heme and the B-helix moves closer to the heme in the WTmetHbthanintherWTmetHbH2O crystal structure, with the result that the ligated water is lost in the latter complex [16,17].Prior ... position E7 as the source of the H- bond to ligand on the basis of apartial sequence, which had indicated a Tyr on the distalE-helix. The similarity in the 1HNMRspectraofthethree globin complexes ... properties of the active site for the cyanomet complex of O2-avid hemoglobin from the trematode Paramphistomum epiclitum Weihong Du1, Zhicheng Xia1, Sylvia Dewilde2, Luc Moens2 and Gerd...