Drug anti-virus docx

DRUG DISCOVERY docx

DRUG DISCOVERY docx

... of cytochrome P450 3A4 and potential drug – drug interactions. Curr. Drug Metab Fruit/Vegetable -Drug Interactions: Effects on Drug Metabolizing Enzymes and Drug Transporters http://dx.doi.org/10.5772/48283 33 Sacrolysin, ... interact with a drug and hence, the response to a drug may differ among indi‐ viduals. Sequence variations in drug- disposition genes can alter the pharm...
Ngày tải lên : 29/03/2014, 21:20
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Báo cáo khoa học: Human liver mitochondrial cytochrome P450 2D6 – individual variations and implications in drug metabolism docx

Báo cáo khoa học: Human liver mitochondrial cytochrome P450 2D6 – individual variations and implications in drug metabolism docx

... therefore serve as an important guideline for determining the dose of anti- depressant drugs and preventing drug- induced toxicity [2–6]. A large majority of studies on the biochemical and genetic ... localization of CYP2D6 may be an important physiological process with a possible role in drug metabolism and drug- induced toxicity. Results Localization of CYP2D6 in human liver mitochondri...
Ngày tải lên : 29/03/2014, 23:20
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Guidance for Industry Botanical Drug Products docx

Guidance for Industry Botanical Drug Products docx

... food, drug, medical device, or cosmetic. Botanical Drug Product; Botanical Drug: A botanical product that is intended for use as a drug; a drug product that is prepared from a botanical drug substance. ... Complex Drug Substances Coordinating Committees in the Center for Drug Evaluation and Research (CDER) at the Food and Drug Administration (FDA). 2 FDA has issued a draft gu...
Ngày tải lên : 30/03/2014, 06:20
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Tài liệu Trình Antivirus miễn phí tốt nhất hiện nay docx

Tài liệu Trình Antivirus miễn phí tốt nhất hiện nay docx

... AVG Anti-Virus Free Edition: Trình Antivirus miễn phí tốt nhất hiện nay AVG Anti-Virus Free Edition 9.0.709 ra mắt được một thời gian. Qua trải nghiệm, tác giả thấy AVG Anti-Virus Free ... dùng phiên bản AVG Anti-Virus Free Edition 9.0.709. Đây được xem là phiên bản miễn phí tốt nhất hiện nay và cách thức sử dụng phần mềm này cũng rất đơn giản. Phiên bản AVG Anti-Virus Free Edit...
Ngày tải lên : 20/01/2014, 16:20
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Tài liệu Báo cáo khoa học: Amprenavir complexes with HIV-1 protease and its drug-resistant mutants altering hydrophobic clusters docx

Tài liệu Báo cáo khoa học: Amprenavir complexes with HIV-1 protease and its drug-resistant mutants altering hydrophobic clusters docx

... in Fig. 1B. Multidrug-resistant mutation V32I, which alters a residue in the active site cavity, appears in  20% of patients treated with APV [14] and is associ- ated with high levels of drug resistance ... MA, Merigan TC & Kovari LC (2005) ‘‘Wide-open’’ 1.3 A structure of a multidrug-resistant HIV-1 protease as a drug target. Structure 13, 1887–1895. 46 Saskova KG, Kozisek M, Rezaco...
Ngày tải lên : 18/02/2014, 04:20
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Tài liệu Báo cáo khoa học: Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2? docx

Tài liệu Báo cáo khoa học: Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2? docx

... interconnected drug binding sites. The present investigation examines the coupling of drug binding to ATP hydrolysis. Initial drug binding to the protein requires a high-affinity interaction with the drug ... multidrug transporters, con- tains more than one drug binding site. In addition, the binding sites are linked by both negative and positive heterotropic allostery. In a departur...
Ngày tải lên : 18/02/2014, 18:20
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Managing Drug Interactions in the Treatment of HIV-Related Tuberculosis docx

Managing Drug Interactions in the Treatment of HIV-Related Tuberculosis docx

... determine pathways of drug metabolism. Furthermore, there are no published studies of possible drug- drug interactions between second-line antituberculosis drugs and antiretroviral drugs. Based on ... populations (young children, pregnant women, patients with drug- resistant tuberculosis). We include drug- drug interaction data for antiretroviral drugs that have been approved or are...
Ngày tải lên : 06/03/2014, 04:20
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Low Occurrence of Tuberculosis Drug Resistance among Pulmonary Tuberculosis Patients froman Urban Setting, with a Long-Running DOTS Programin Zambia docx

Low Occurrence of Tuberculosis Drug Resistance among Pulmonary Tuberculosis Patients froman Urban Setting, with a Long-Running DOTS Programin Zambia docx

... access to drug susceptibility testing (DST) is limited and not performed routinely, the picture of drug resistance in Zambia may be imprecise. This study was set out to document the prevailing drug ... levels of any resistance to first-line drugs (8.8%) in Ndola, and for the first time systematically investigated and documented absence of resistance to second-line drugs (OFL and KAN). The...
Ngày tải lên : 22/03/2014, 18:20
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Radiological Findings of Extensively Drug-Resistant Pulmonary Tuberculosis in Non-AIDS Adults: Comparisons with Findings of Multidrug-Resistant and Drug-Sensitive Tuberculosis docx

Radiological Findings of Extensively Drug-Resistant Pulmonary Tuberculosis in Non-AIDS Adults: Comparisons with Findings of Multidrug-Resistant and Drug-Sensitive Tuberculosis docx

... TB = drug- sensitive tuberculosis, MDR TB = multidrug-resistant tuberculosis, XDR TB = extensively drug- resistant tuberculosis, GGO = ground-glass opacity Fig. 1. Findings for extensively drug- resistant ... parentheses are median, standard error and range. DS TB = drug- sensitive tuberculosis, MDR TB = multidrug-resistant tuberculosis, XDR TB = extensively drug- resistant tuberculosis,...
Ngày tải lên : 22/03/2014, 18:20
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