NON-VIRAL GENE THERAPY pptx
Báo cáo khoa học: Recombinant derivatives of the human high-mobility group protein HMGB2 mediate efficient nonviral gene delivery pptx
... barriers in gene transfer. Hum Gene Ther 12, 861–870. 16 Wiethoff CM & Middaugh CR (2003) Barriers to non- viral gene delivery. J Pharm Sci 92 , 203–217. Recombinant HMGB2 mediates gene delivery ... carriers in gene transfer. Gene Ther 4, 586–592. 8 Demirhan I, Hasselmayer O, Chandra A, Ehemann M & Chandra P (1998) Histone-mediated transfer and expression of the HIV-1 tat...
Ngày tải lên: 16/03/2014, 22:20
NON-VIRAL GENE THERAPY pptx
... method. Nucleic acids research, 31(15), e81. Non-Viral Gene Therapy 20 gene therapy for cystic fibrosis requires only partial gene correction. Gene therapy, 3(9), pp. 797-801. Eastman, SJ., ... This form of gene therapy is being used at most genetic engineering laboratories throughout the world. Clearly, gene therapy provides great opportunities for treating di...
Ngày tải lên: 27/06/2014, 18:20
TARGETS IN GENE THERAPY pptx
... treatment with radiotherapy or chemotherapy. Another approach to cancer gene therapy is gene- directed enzyme prodrug therapy (GDEPT). GDEPT transfers an activating transgene into tumor cells ... Strategy in Gene Therapy Choosing Targets for Gene Therapy 9 Gene therapy of human β-thalassemia is still in its infancy and requires the development of efficient, safe a...
Ngày tải lên: 28/06/2014, 05:20
GENE THERAPY pptx
... that mice have a gene that is similar to the human HD gene. Gene therapy trials for HD are in the planning stage. (See the gene therapy updates in chapter 8 for additional information.) Genetic Disorders ... Joseph. Gene Therapy : treating disease by repairing genes / Joseph Panno. p. cm. — (The “new biology” series) Includes bibliographical references and index. ISBN 0-8160-4...
Ngày tải lên: 29/06/2014, 11:20
nonviral vectors for gene therapy, methods and protocols
... by Mark A. Findeis Nonviral Vectors for Gene Therapy Methods and Protocols Humana Press Humana Press Edited by Mark A. Findeis Nonviral Vectors for Gene Therapy Methods and Protocols Lipid–ODN ... Bos. References 1. Behr, J. P. (1993) Synthetic gene transfer vectors. Acc. Chem. Res. 26, 274–278. 2. Ledley, F. D. (1997) Pharmaceutical approach to somatic gene therapy. Pharm. Res....
Ngày tải lên: 11/04/2014, 09:59
Báo cáo sinh học: "Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma" pptx
... effectively co- operate with HRP/IAA gene therapy. Another major focus of the present study was to evaluate whether sui- cide gene therapy plus immuno -gene therapy had any toxicity on the treated ... of a therapeutic gene to cancer cells. Gene directed enzyme/prodrug therapy (GDEPT) or suicide gene therapy using viral vectors is an attracti ve alternative approach to canc...
Ngày tải lên: 18/06/2014, 19:20
![Báo cáo y học: "Comparison of osteogenic potentials of human rat BMP4 and BMP6 gene therapy using [E1-] and [E1-,E2b-] adenoviral vectors"](https://media.store123doc.com/images/document/12/to/qp/medium_qpq1351678087.png)
Báo cáo y học: "Comparison of osteogenic potentials of human rat BMP4 and BMP6 gene therapy using [E1-] and [E1-,E2b-] adenoviral vectors"
... E2b genes and the use of homologous (rat) BMP genes do not improve the osteogenic potential of direct BMP adenovirus vector gene therapy, the results of this study indicate that BMP gene therapy ... vector and to its transgene. J Immunol 1997; 159:685-93. 43. Varady P, Li JZ, Cunningham M, et al. Morphologic analysis of BMP-9 gene therapy- induced osteogenesis. Hum Gene Ther...
Ngày tải lên: 31/10/2012, 17:08
Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"
... to human germline gene therapy. 2. Criteria for Assessing Applicability to Human Germline Gene Therapy An ideal gene transfer system in the context of human germline gene therapy would have ... important advances in gene transfer technology. K K e e y y w w o o r r d d s s gene targeting; gene therapy; genetic modification; pronuclear microinjection; sperm-medi...
Ngày tải lên: 03/11/2012, 10:01
sermina lieu phap gen human gene therapy
... Simplex. nguyenthanhloi_2@yahoo.com 18 TRƯỜNG ĐH TÂY NGUYÊN KHOA KHTN & CN LIỆU PHÁP GEN (Human Gene Therapy) GVHD: Võ Thị Phương Khanh SVTH: Nguyễn Thành Lợi Hồ Thị Lan Anh Nguyễn Thị Trang nguyenthanhloi_2@yahoo.com ... nhằm tạo ra thế hệ sau bình thường. nguyenthanhloi_2@yahoo.com 6 Sử dụng các gen tự sát (Suicide gene) và gen độc tố đưa vào tế bào mới bị xâm nhiễm HIV cũng...
Ngày tải lên: 06/09/2013, 22:49
Improvement of different vaccine delivery systems for cancer therapy pptx
... development and cancer gene therapy. Curr Gene Ther 2010, 10:56-76. 46. Kim-Schulze S, Kaufman HL: Gene therapy for anti-tumor vaccination. In Methods in Molecular Biology, Gene Therapy of Cancer ... gene therapy trials. In current study, a retroviral vector was encapsulated with genetic segment bearing both IL-12 and herpes simplex virus thymidine kinase (HSV-tk) genes [42]....
Ngày tải lên: 06/03/2014, 02:21