... Performance Computing in Science and Engineering ’10,DOI10.1007/978-3-642-15748-63,© Springer-Verlag Berlin Heidelberg 201129Massive and Massless Four-Loop Integrals 23Fig. 2. CPU-time and speedup ... XAu24(SR)18isomers C, V and U.PdandPt atoms are drawn in black, Au in orange or purple, Ag in grey, Cl or I in green,Sinyellow,PinblueandHinwhiteinvestigated1 in contrast to earlier calculations ... excellent software and methods to address – and solve – the most de-manding problems in science and engineering. The success of this approach isof significant importance for our community and will also...