Báo cáo hóa học: " New Insights into the RLS Algorithm" pdf

... proteins were sequenced. Of these, 10 clones were found to encode the LC2 and LC1 sub- units. Others were found to encode other variants of the C-lectin-like venom proteins. The amino acid sequences ... 3944–3958 ª 2008 The Authors Journal compilation ª 2008 FEBS 3945 the corresponding D ion. Third, the 0,4 A ion would include the 6-arm substituents, but not the extra Glc- NAc...

Ngày tải lên: 07/03/2014, 06:20

... concentration, the rate of their passive diffusion through the plasma membrane and then the kinetic parameters characteristic of their P-gp-mediated efflux. Our data show that the efficiencies of the P-gp-mediated efflux ... the measurement of the rate of passive diffusion of the dye through the plasma membrane. This cannot be done by the simple measurement of the increase...

Ngày tải lên: 08/03/2014, 08:20

... Finally in 1996 these micropar- ticles were recognized for their central role in antigen pres- entation with the work of Graça Raposo and Hans Geuze of Utrecht University in the Netherlands, who ... cell cross-priming through the expression of HLA/peptide complexes [6]. Based on these and following observations about the role of exosomes in antigen presentation, the exacerbated prod...

Ngày tải lên: 18/06/2014, 15:20

... about the pathogenesis of these disorders suggest that not only the decline in CD4 + T cell counts [6], but also the shift into a Th2 cytokine profile [7], the molecular mimicry [8] and the over-expression ... by S. aureus [9]. These superantigens penetrate the skin and bind to Langerhans cells, thereby stimulating the release of IL-4 and IL-5, which further enhance the prod...

Ngày tải lên: 20/06/2014, 08:20

... perturbations in the vicinity of the introduced mutation, with the overall fold conserved. The data presented here represent the first biophysi- cal characterizations of the KH domains of dFXRP. The structure ... FMRP function as the primary cause of the syndrome. In spite of its key importance, the effect of the I304N mutation on the structure and function of FMRP is s...

Ngày tải lên: 30/03/2014, 15:20

... maintained together in either the test set or the working set. Although the data could be processed up to 2.5 A ˚ , there were some practical problems in using the full dataset in the refine- ment – the ... in the orientation of the P3 moiety is further influenced by the different orienta- tion pattern of the individual P2 Leu residues. In erva- tamin-A, the P3 moiety of b...

Ngày tải lên: 18/02/2014, 16:20

... while the remaining subunits of the bc 1 complex are encoded in the nucleus, synthesized by cytosolic polysomes, and then imported into mitochondria, thereby reaching their final location in the ... known about the function of the seven supernumerary subunits. To gain fur- ther insight into the function of the supernumerary subunits in the assembly process, we have examin...

Ngày tải lên: 19/02/2014, 12:20

... clarify whether these enzymes do indeed fulfil their predicted function, and how the properties of the enzymes differ from those of the homologous enzymes from O. formigenes. Although the crystal ... atom pairs). The locations of the cofactor ThDP and the activator ADP are clearly defined in the electron density map. In contrast, electron density of the S-acetyl pantetheine mo...

Ngày tải lên: 06/03/2014, 11:20

... between the CPRP and the mature hormone sequence, the posi- tion of the six cysteyl residues in the sequence, the size of the putative mature peptide (72 amino acid resi- dues), and presence of the ... revealed the existence of two distinct groups of neurons: the major- ity of them were stained only by the anti-CHH serum, and therefore probably represent the CHH secret...

Ngày tải lên: 23/03/2014, 07:20

... the KNR refinery, an unlikely finding that signals the presence of misclassification problems. In retrospect, the Pedersen et al. [1] study was the first human health study to raise the hypothesis ... evidence standard [63] to examine the support for the soluble nickel cancer hypothesis; and have presented new findings and new analyses of existing findings of the human hea...

Ngày tải lên: 20/06/2014, 00:20