báo cáo hóa học:" The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer" docx

... start of the NK cell-based therapy, the anastomotic relapse before start of the NK cell-based therapy and the duodenom metastases after finishing the NK cell-based therapyCell marker Primary ... purposes)line phosphatase, γ-glutamine transferase, alanine ami-notranferease (ALT), aspartate aminotransferase (AST),lactate dehydrogenase, Quick, and aPTT were determinedbefore each leukapheresis. ... commercial ELISA kits.BioMed CentralPage 1 of 18(page number not for citation purposes)Journal of Translational MedicineOpen AccessResearch Anti-tumor activity of patient-derived NK cells after...

... 0.05.Results The patterns of expression of IDO and Bin1 The expression of IDO was detected in the cytoplasm of tumor cells, normal epithelium, and immune cells. The staining of IDO occurred on both the ... MedicineOpen AccessResearch The paradoxical patterns of expression of indoleamine 2,3-dioxygenase in colon cancerYan-Fang Gao†1,2,3, Rui-Qing Peng†1,2, Jiang Li1,2, Ya Ding1,2, Xing ... dietary tryptophan enters the kynurenine pathway,leading to the biosynthesis of NAD or resulting in the complete oxidation of amino acids for energy production. Indoleamine 2,3-dioxygenase (IDO)...

... 8 :11 7http://www.translational-medicine.com/content/8 /1/ 117 Page 2 of 6COMM E N T ARY Open Access The emerging role of insulin-like growth factor 1 receptor (IGF1r) in gastrointestinal stromal tumors (GISTs)Maria A Pantaleo 1, 2*, Annalisa ... growing interest in insulin-like growth fa ctor 1 receptor (IGF1R) in medical oncology.IGF1R is a tyrosine kinase receptor that binds bothIGF1 and IGF2 [1] . After ligand binding, the tyrosinekinase ... Astolfi 1, 2, Margherita Nannini 1 , Guido Biasco 1, 2AbstractRecent years have seen a growing interest in insulin-like growth factor 1 receptor (IGF1R) in medical oncology.Interesting data...

... psychometric validation of a US English satisfaction measure for patients with benign prostatic hyperplasia and lower urinary tract symptomsLibby Black*1, Alyson Grove2 and Betsy Morrill1Address: ... interpretation of data and drafting the manuscript. BM participated inthe acquisition of data and the revision of the manuscript.All authors read and approved the final manuscript.AppendicesAppendix ... outcome measure designed to evaluate patient satisfaction with treatment for BPH by evaluating patient perceptions of change and their satisfaction with that change. Using datafrom a randomized...

... moderate and severe) and of patients after primary TKA, and after a revision of the TKA. All patients filled in the Dutch KOOS questionnaire, as well as the SF-36 and a Visual Analogue Scale for ... CentralPage 1 of 11(page number not for citation purposes)Health and Quality of Life OutcomesOpen AccessResearch The Dutch version of the knee injury and osteoarthritis outcome score: A validation ... the start of the present study almostno reliable and validated Dutch versions of disease-spe-cific questionnaires were available to evaluate the func-tional status of patients and quality of...

... purposes)Health and Quality of Life OutcomesOpen AccessResearch The Pediatric Quality of Life Inventory™ (PedsQL™) family impact module: reliability and validity of the Brazilian versionAna C Scarpelli1, ... the impact of chronic medical conditions on the HRQOL of parents and family functioning. The objective of the present study was to evaluate the psychometric properties of the PedsQL™ Family Impact ... regarding the reliability and validity of the construct. This suggests its usefulness asa parameter in studies assessing the impact of pediatric cancer on the HRQOL of parents and family functioning.The...

... suggests that most of the diversity in the marine RNA virus community remains uncharacterized.Furthermore, these results raise the hypothesis that the genomes of these marine RNA viruses that we ... not for citation purposes)Virology JournalOpen AccessResearch The complete genomes of three viruses assembled from shotgun libraries of marine RNA virus communitiesAlexander I Culley1, ... polycistronicpicorna-like viruses is an important component of the RNA virioplankton in coastal waters. Nevertheless, asexemplified by the SOG genome from the Strait of Geor-gia site, other marine RNA virus...

... JournalOpen AccessResearch The E5 protein of the human papillomavirus type 16 down-regulates HLA-I surface expression in calnexin-expressing but not in calnexin-deficient cellsMyriam Gruener1, ... trafficking of the HLA-I complex to the plasma mem-brane, leading instead to its accumulation in the ER/Golgi of the infected cell. A direct binding of E5 to the heavychain of HLA-I seems under the ... of 15(page number not for citation purposes)HPV16 E5 decreases HLA-I surface expression in calnexin-containing but not in calnexin-deficient cellsFigure 2HPV16 E5 decreases HLA-I surface expression...

... citation purposes)Virology JournalOpen AccessResearch The internal initiation of translation in bovine viral diarrhea virus RNA depends on the presence of an RNA pseudoknot upstream of the initiation ... features of internal initia-tion of hepatitis C virus RNA translation. EMBO Journal 1995,14(23):6010-6020.11. Jackson RJ, Kaminski A: Internal initiation of translation in eukaryotes: the picornavirus ... initi-ation of translation. If the region in question is an IRES, translation of the second cistron may occur via internal entry of ribosomes in contrast to re -initiation which ispossible only under...

... by the method of Reed and Muench [40]. Activation and inhibition of the Raf/MEK/ERK signal cascade Activation of the Raf/MEK/ERK signal cascade wasachieved by artificial stimulation of MDCK cells ... for citation purposes)Virology JournalOpen AccessResearch Higher polymerase activity of a human influenza virus enhances activation of the hemagglutinin-induced Raf/MEK/ERK signal cascadeHenju ... capacity was related to the IVA's ability to activate the Raf/MEK/ERK (MAPK) signal cascade. The H3N2 virus upregulated MAPK signaling better than did the H1N1 virus. Accordingly, stimulation...

... article as: Lane et al.: The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer. Journal of Ovarian Research 2010 ... 3:1http://www.ovarianresearch.com/content/3/1/1Page 2 of 10invasion of ovarian tumor s [27]. Activation of this path-way has been associated with cisplatin resistance in ovarian cancer [28]. In addition, the inhibition of Aktprevents the ... diseases against TRAIL- induced cell d eath.Most of ovarian cancer ascit es (82%) led to some degree of inhibition of TRAIL- induced apoptosis as demon-stratedbyanincreaseofTRAILIC50 with ascites...

... purposes)BackgroundThis paper describes the development and validation of a very brief measure of peritraumatic autonomic activation,the STRS (Shortness of Breath, Tremulousness, Racing Heart, and Sweating) checklist. ... CentralPage 1 of 8(page number not for citation purposes)Annals of General Hospital PsychiatryOpen AccessPrimary researchThe STRS (shortness of breath, tremulousness, racing heart, and sweating): ... HI, USA and 2Department of Psychology, University of Hawaii at Manoa, Honolulu, HI, USAEmail: HS Bracha* - H.Bracha@med.va.gov; Andrew E Williams - awilliam@crch.hawaii.edu; Stephen N Haynes...