Báo cáo hóa học: " Constancy and diversity in the flavivirus fusion peptide Stephen J Seligman" ppt

... the implications of the fusion peptide differ-ences between CFRV and the other flaviviruses? The changes in eight of the 16 amino acids in CFRV in the sequence homologous to the flavivirus fusion ... domain I, four pairs in domain II (including the fusion- peptide related pair) and one pair in domainIII were present in both the arthropod-borne flaviviruses and the CFRV (Figure 1). However, the ... the fusion peptide and the patternof disulfide linkages in protein E differed significantly from the other flaviviruses.Conclusion: The constancy of the canonical fusion peptide sequences in...

Báo cáo hóa học: " Endotoxin and CD14 in the progression of biliary atresia" ppt

... CD14 production in the liver and the subsequent effects on LPS-inducedliver injury during BA is not clear. In this study, we investigated the role of CD14 in BA-associated liver injury, with particular ... cleared from the circulationwithin a few minutes of intravenous injection, and the majority of LPS is traced to the liver [6,7]. In additionto clearing LPS, the liver also responds to the presenceof ... 14Figure 10 Endotoxin staining in the liver tissues of rats. Immunohistochemical stain of the liver sections using a monoclonal antibodyagainst lipid A shows positive staining in the Kupffer cells,...

báo cáo hóa học:" Macrophages and cytokines in the early defence against herpes simplex virus" potx

... overlappingkinases and nuclear binding proteins in their signallingpathway and thus have overlapping functions [178]. The final functional capacity of the effector cell thus reflects the cytokine ... firstcytokines described in detail, and thus provided the fun-damental basis for the understanding of the cytokine con-cept [183]. The IFNs are divided into three major groups. The two original ... Furthermore, the tegument proteins have been shown to induce cellularinhibitors of the JAK/STAT pathway, resulting in inhibi-tion of both IFN signalling and production [341,342]. The IE protein...

Báo cáo hóa học: " Air ambulance services in the Arctic 1999-2009: a Norwegian study" pptx

... snowmobileinjuries were registered [15]. Most i njuries (79.4%)occurred in the time period between March and May.This is in accordance with the peak of fractures in Aprilshown in our survey. In the ... impor-tant for the hasty transfer of patients to the mainlandfor CT scanning.We have documented the logistics of the air ambu-lance service in the Norwegian Arctic and the varia-tions around the year. ... taken care of by the Lynx or Super Puma crews are thus indirectlyincluded in our survey. The NAF’s Sea King helicoptersoperate on t he Norwegian mainland and along its coast-line. They very rarely...

báo cáo hóa học: " Type D personality in the general population: a systematic review of health status, mechanisms of disease, and work-related problems" docx

... letters to the editoretc.), (3) if they were published in peer-review journals, and (4) if they were written in English. Studies wereexcluded for the following reasons; (1) if they included apatient ... dur-ing experimental stress. Type D was also associated witha decreased activity in the amygdala in response to fear-ful expressions [10], suggesting inadequate emotion-pro-cessing in the brain. ... disease-promoting mechanisms and work-related problems in apparently healthy individuals.Introduction In the past decade, studies on the effects of Type D per-sonality on clinical and psychological...

báo cáo hóa học: " Development and validation of the insulin treatment appraisal scale (ITAS) in patients with type 2 diabetes" docx

... striking. Yet, still 36% of the insulin-treatedpatients agree to the item that injecting insulin is painful,compared to 43% in the insulin-naïve group. This sug-gests that despite improved injection ... insulin-treated agreed thatinsulin causes weight gain, compared to 23% in the insu-lin naïve. The highest mean score for insulin-naïvepatients was on the item pertaining to the belief that insu-lin ... participated in the conceptualisation and design of the original web-based survey. FJS, SES and FP assessed the quality of the data collected and participated in the design of the validation study and the...

báo cáo hóa học: " Reliability and validity of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire in dyspepsia: A six-country study" pptx

... low internal consistency in the Abdominalpain domain probably reflects the difficulty of measuringthis often fluctuating symptom, as well as the fact that the GSRS Abdominal pain domain contains ... domains. Correlation was significantfor the relevant GSRS Abdominal pain domain and mostor all QOLRAD domains in the majority of the differentlanguage versions. The GSRS Abdominal pain domainalso ... most or all domains in the Hungarian and German translations of the QOLRAD,but only for one domain in the Spanish version and for nodomains in the Afrikaans and Polish versions of the QOL-RAD....

báo cáo hóa học:" Mechanically-induced osteogenesis in the cortical bone of pre- to peripubertal stage and peri- to postpubertal stage mice" ppt

... puberty and endocortical expansion in the postpubertal stage[8,10], but the effects of loading and estrogen may beindependent of each other [11]. The aim of this study is tofurther examine the ... environment.MethodsForty-two virgin female mice of the strain C57BL/ 6J wereused in the experiment (Jackson Laboratory, Bar Harbor,ME). Mice were housed in 153 in 2 cages and providedwith food and water ad libitum. ... humans.Activity during this time period may be particularlyimportant for adding bone mass and minimizing the riskof bone loss and fracture in adulthood. Clearly the effectsof age on the location and rate...

báo cáo hóa học:" Repositioning and stabilization of the radial styloid process in comminuted fractures of the distal radius using a single approach: the radio-volar double plating technique" pot

... and drafting of the manuscript.GK participated in the design of the study and coordination and helped todraft the manuscript. All authors read and approved the final manuscript.Competing interestsThere ... were placed on the operating table in the supine position with abduction of the arm and supina-tion of the forearm. A tourniquet was used, and stan-dard disinfection and draping carried out. ... be the case in joint depression fractures, in fractures with com-pletely displaced joint fragments or in fractures of the dorsal rim. These fractures are therefore also i nap-propriate for the...

báo cáo hóa học: " Reliability and validity of the Spanish version of the 10-item Connor-Davidson Resilience Scale (10-item CD-RISC) in young adults" potx

... version = 0.85 and of the Spanish version = 0.85), and the weights in factor analy-sis w ere within the range of 0.48-0.76 on our sc ale and within the range of 0.44-0.74 in the original. The factor ... evaluate the validity and reliability of the Spanish version of the 10-item CD-RISC in young adults of Cuenca, Spain, in addi-tion to verifying the single dimension factor structure.FindingsStudy ... structure d in a single dimension as in the original English version.Findings: Cross-sectional observational study including 681 university students ranging in age from 18 to 30 years. The number...

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