Báo cáo hóa học: " Structural comparisons of the nucleoprotein from three negative strand RNA virus families" pot

... structure and function of the N proteins among negative strand RNA viruses. Implication of the hypothesis The structural alignments of the N proteins from three negative strand RNA virus families have ... Abstract Structures of the nucleoprotein of three negative strand RNA virus families, borna disease virus, rhabdovirus and influenza A...

Ngày tải lên: 18/06/2014, 18:20

... either one of the three inner-core heptose residues of H. influenzae LPS [14,17,19]. The lic1 locus of H. influenzae controls both the expression and phase variation of the PCho epitope [36]. The ... the steps in the biosynthesis of the oligosaccharide portion of the LPS molecules. Molecular structural studies o f LPS from mutant a nd wild-type strains of H...

Ngày tải lên: 31/03/2014, 21:21

... Thus inferred from the relative rates of fragment formation, the cleavages of the sites were in the order: Tyr146/Asn147 ! Phe114 ! other sites. The weakness of bands of fragments I and IV and the appearance ... appearance of fragment II in the degradation of the Tyr146!His/Asn147!Ser mutant (panel d) indicated a significant decrease in the rate of cleavage o...

Ngày tải lên: 22/02/2014, 07:20

... responsible, from a thermodynamic point of view, for the binding of the monomeric species of CAC? We have previously discussed the variation in the free energy of binding as a function of the changes ... relationship between S 2 and the location of structural elements (Fig. 4). Furthermore, the R ex terms are distributed throughout the 3D structure of the p...

Ngày tải lên: 07/03/2014, 06:20

... identified by the mass increase of 42 mass units. The relative level of acetylation of a peptide was estimated on the basis of the intensity ratio of the native and acetylated species. From the data ... a-helix in the whole protein, and the 1–70 region is poorly structured. SDS increases the a-helix content of proteins revealing the helical potential. The a-...

Ngày tải lên: 07/03/2014, 14:20

... diminished Fig. 5. Model of the acceptor end of tRNA Ser bound in the active site of mMbSerRS. The view is focused on the acceptor part of tRNA in the active site of mMbSerRS. The tRNA is shown as an orange ... Switzerland The fidelity of protein synthesis depends on the correct attachment of amino acids to the 3¢-ends of their cog- nate tRNA species by aminoa...

Ngày tải lên: 16/03/2014, 06:20

... study the secondary structure of the catalytic domain of PKCf and the effect of its substrate, MgATP, and also to study the effect of thermal unfolding in the presence and the absence of MgATP. ... structure of 282 residues of a total of 344 have been solved [19]. The catalytic domain of PKCh possesses a high degree of homology ( 80%) with the catalytic do...

Ngày tải lên: 16/03/2014, 13:20

... functional studies of Nog o-A. On the other hand, the recent identification of Nogo-40 as a potent NgR antagonist suggests a promising starting point for the design of potential therapeutic agents ... undetectable in five of the 10 selected structures. Figure 8E shows a represen- tation of the e lectrostatic potential associated with the contact s urface of the N ogo-4...

Ngày tải lên: 16/03/2014, 16:20

... of note that the structure of the LPS O-antigen of F. columnare differs structurally from the LPS O-antigen of the fish pathogen Flavobacterium psychrophilium [21], which is a linear polymer of ... However, the nature of the adhesins involved have not been identified, but possible candidates are LPS, capsule, fimbriae or other appendages of the bacterium, a hypothes...

Ngày tải lên: 17/03/2014, 10:20

... for formation of short helices, transiently, and the chain as such is highly dynamic. Structure of the core of the oligomers Because of the large size of the core of the oligomer, the NMR spectra ... signals from the interior of the core and thus do not give any informa- tion on its structural details. Nevertheless, we did derive useful insights into the...

Ngày tải lên: 23/03/2014, 11:20