Báo cáo hóa học: " Trichloroethylene exposure and somatic mutations of the VHL gene in patients with Renal Cell Carcinoma" potx

... been confirmed with the cloning of the VHL gene and the identification of germline and somatic mutations of this gene in VHL patients and sporadic RCC. Today, more than 400 germline mutations have ... purposes) Sequence chromatograms of the 4 mutations identified in the VHL gene in this studyFigure 1 Sequence chromatograms of the 4 mu...

Ngày tải lên: 20/06/2014, 00:20

... determined from the point on the ROC curve having the minimum distance from the point corresponding to sensitivity and specificity values of 1.0. Contingency table analysis of data obtained using the ... in Pfizer Inc., and was a paid contractor to Pfizer Inc. in the development of this manuscript and the analysis and interpretation of data involving circulat...

Ngày tải lên: 20/06/2014, 04:20

... validity. Competing interests The authors declare that they have no competing interests. Authors' contributions MSY was the main investigator and analysed the data and wrote the first draft. AI and ... functioning [7]. We were therefore interested in testing this hypothesis and examining whether there is a relationship between psychological distress and vitality. The...

Ngày tải lên: 18/06/2014, 19:20

... being administered to the same delegate by sampling within concurrent sessions and displaying a slide before each ses- sion informing delegates of the purpose of the survey and requesting their ... significantly to the success of the project, G.G. Wolvaardt for providing the authors with an understanding of historical IAC events contributing to the explanation...

Ngày tải lên: 20/06/2014, 08:20

... shown in Table 2. The results indicated that S. aureus was the most sensitive strain to the oil of L. resedifolia with the strongest inhibition zone (37 mm) and a MIC value of 0.09 mg/mL. The ... effect of the essential oils of L. resedifolia. There no reports on the essential oils of the species of the genus launaea except that reported by Cheriti et al...

Ngày tải lên: 21/06/2014, 17:20

... as the diameter of the inhibition zone in millimeter. Results obtained in the antibacterial study are shown in Table 2. The results indicated that S. aureus was the most sensitive strain to the ... report here the findings of our studies on the composition and anti- microbial activity of L. resedifolia essential oils. The spe- cies was collected during the fl...

Ngày tải lên: 21/06/2014, 19:20

... collected all the patient data and drafted the manuscript. BF participated in the design of the study. JEN participated in the design of the study, and collection of medical records data by reviewing the ... from the date of return of the questionnaires. The International Classifi- cation of diseases (ICD) version 9 was used when including patients in...

Ngày tải lên: 20/06/2014, 15:20

... stabilizing the tran- scription factor HIF-1a through inhibition of HIF-1a binding to VHL [10]. These and other findings strongly implicate angiogenesis in the pathophysiology of HCC (reviewed in ... in Pfizer Inc., and was a paid contractor to Pfizer Inc. in the development of this manuscript and the analysis and interpretation of data involving circulating...

Ngày tải lên: 18/06/2014, 22:20

... the coordination of the data collection and in the critical revision of the study. BM and GE participated in the exposure assessment and in the critical revision of the manuscript. ES is the data ... participated in the design of the study, drafted the manuscript and performed the statistical analysis. MM participated in the statistical an...

Ngày tải lên: 20/06/2014, 00:20