báo cáo hóa học: " Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice" pot
Tài liệu Báo cáo Y học: Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation ppt
... phosphorylation of Ó FEBS 2002 NAMI-A affects c-myc gene expression and MEK/ERK phosphorylation (Eur. J. Biochem. 269) 5869 Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A ... counteracted, and ultimately abolished, the increase in c-myc gene expression elicited by PMA in serum-free cells. These results suggestthat inhibition of MEK/ERK signaling by NAMI-A mayhave an ... heavily suggests that the inhibitory effect of NAMI-A on c-myc gene expression mayhave occurred by suppressing ERK1/2 activation and activity elicited by PMA-generated signals.Unlike the ras gene...
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Báo cáo khoa học: Inhibition of the NF-jB transcriptional activity by protein kinase A pot
... 2002 Inhibition of the NF-jB transcriptional activity by protein kinase A Naoko Takahashi, Toshifumi Tetsuka, Hiroaki Uranishi and Takashi OkamotoDepartment of Molecular Genetics, Nagoya City University ... examined whether cAMP and PKAmodulates NF-jB activity and found that the cAMP/PKAsignaling pathway inhibits the NF-jB activity by acting on the transactivation domain of p65. Possible mechanisms ... VCAM-1mediated by IL-1b or TNFa [15,16]. Thus, elevation of intracellular cAMP and/or activation of PKA appear tomodulate the transcriptional activity of NF-jBinanegative way.In this report, we examined...
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Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot
... into contact in the absence of ATP, curcumin is then able tobind to the ATPase (possibly at the hinge region) locking the two domains together and therefore precluding ATP binding(i.e. inhibiting ... point is the mean ^ SD of three determinations.q FEBS 2001 Inhibition of the Ca2þ-ATPase by curcumin (Eur. J. Biochem. 268) 6323 Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively ... possiblyincreased. In order to further assess the possibility of curcumin affecting the interaction of ATP binding to the ATPase, thiswas directly measured using [32P ]ATP in the absence of Ca2þ(Fig....
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Báo cáo khoa học: Inhibition of the mitochondrial calcium uniporter by the oxo-bridged dinuclear ruthenium amine complex (Ru360) prevents from irreversible injury in postischemic rat heart docx
... assessing the relevance of mPTP in I⁄ R injury in the intact heart is the Fig. 6. The oxygen-bridged dinuclear ruthenium amine complex (Ru360) does not inhibit calcium movements in sarcoplasmic ... assuming aFig. 4. Perfusion of the oxygen-bridged dinuclear ruthenium amine complex (Ru360) into isolated hearts inhibits the mitochondrial cal-cium uptake. Initial calcium in ux rate of mitochondria ... SRvesicles or in isolated myocytes [15]. To gain insightinto the contribution of the mitochondrial uniporter to myocardial injury during I ⁄ R in isolated hearts,we examined the ability of perfused...
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Báo cáo khoa học: Inhibition of the D-alanine:D-alanyl carrier protein ligase from Bacillus subtilis increases the bacterium’s susceptibility to antibiotics that target the cell wall potx
... 2993–3003 ª 2005 FEBS Inhibition of the D-alanine:D-alanyl carrier protein ligase from Bacillus subtilis increases the bacterium’s susceptibility to antibiotics that target the cell wall Juergen J. ... inhibitor. To test if the inhibitor 5 was able to penetrate the cell wall to reach its target DltA, we investigated chan-ges in the growth rates of the Gram positive wildtype strains B. subtilis ... 5).Discussion The biosynthesis of d-alanyl-lipoteichoic acid requiresfour proteins that are encoded by the dlt operon [5]. The synthesis starts with the selection of the d-Alaby the 57 kDa d-Ala-d-Ala carrier...
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báo cáo hóa học: " Validation of the Clinical COPD Questionnaire (CCQ) in primary care" docx
... [3,5,7]. The questionnaireswere filled in before meeting the health professional, i.e. the GP or a nurse. During the meeting The GP or a nurse(according to local routines) estimated if and how the patients' ... 0.83#Reliability of instruments evaluated on the stable subgroup in the entire study sample with clinical COPD. *Reliability of instruments evaluated on the stable subgroup in the group with verified COPD. ... 99:493-500.7. Kooi HH, Tuinenga MG, Schokker S, Molen T van der: How tomeasure Clinical Control in Patients with COPD. The Devel-opment of the Clinical COPD Questionnaire (CCQ). QoLNewsletter...
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báo cáo hóa học: " Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice" pot
... NeuroinflammationOpen AccessResearch Inhibition < /b> of < /b> the < /b> alternative < /b> complement < /b> activation < /b> pathway < /b> in < /b> traumatic < /b> brain < /b> injury < /b> by < /b> a < /b> monoclonal < /b> anti-factor < /b> B antibody: a < /b> randomized placebo-controlled study in < /b> miceIris ... expression.Conclusion: Inhibition < /b> of < /b> the < /b> alternative < /b> complement < /b> pathway < /b> by < /b> posttraumatic administration of< /b> a < /b> neutralizing anti-factor < /b> B antibody appears to represent a < /b> new promising avenue forpharmacological attenuation ... extrapolate thesefindings to a < /b> pharmacological model by < /b> targeted inhibi-tion of < /b> the < /b> alternative < /b> pathway < /b> [35]. We therefore used a< /b> newly available, highly specific and potent inhibitor of< /b> the < /b> alternative...
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Báo cáo hóa học: " Impairment of the CD8+ T cell response in lungs following infection with human respiratory syncytial virus is specific to the anatomical site rather than the virus, antigen, or route of infection" pdf
... life.Results: To determine whether this effect is dependent on the virus, the route of infection, or the type of infection (respiratory, disseminated, or localized dermal), we compared the CTL responses in ... subset of the virus- specific CD8+ cytotoxic T lymphocytes (CTL) isolated from the lungs of mice infected with human respiratory syncytial virus (RSV) is impaired in the ability to secrete interferon ... lung. Thus, it is not the virus bearing the epitope norlocal virus replication that results in the decreased func-tionality of CD8+ CTL in lungs, but rather the pulmonary site of residence of the...
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Báo cáo hóa học: " Inhibition of G1P3 expression found in the differential display study on respiratory syncytial virus infection" docx
... purposes)Virology JournalOpen AccessResearch Inhibition of G1P3 expression found in the differential display study on respiratory syncytial virus infectionDongchi Zhao*1,2, Dan Peng1, Lei Li2, ... is the primary initiator of pulmonary inflammation in RSV infections, whichcause significant perturbations of global gene expression controlling multiple cellular processes. In this study, differential ... α/β interferon-inducible gene expression byupregulation of MG11 and downregulation of G1P3. Conclusion: RSV replication could induce widespread changes in gene expression including bothpositive...
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Báo cáo hóa học: " Inhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating MLV-derived retroviral vectors" pdf
... CentralPage 1 of 12(page number not for citation purposes)Virology JournalOpen AccessResearch Inhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating ... loss of a small part of the R region in the LTR. Their results also suggested a negative interfer-ence of the tyrosinase enhancer on the viral enhancerwhen the latter was retained in the 3'LTR. ... involved in enhanced SINCMV titers. Our results show that treatment of the SINCMV retroviral producer cells with 3 µM TsAresulted in a significant increase in titer indicating that histone deacetylation...
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báo cáo hóa học:" Inhibition of Henipavirus fusion and infection by heptad-derived peptides of the Nipah virus fusion glycoprotein" doc
... membrane fusion. Peptides Inhibition of Hendra virus and Nipah virus infection by N-terminal and C-terminal pegylated heptad peptidesFigure 6 Inhibition of Hendra virus and Nipah virus infection by ... availability of NiV in the Inhibition of Hendra virus and Nipah virus infection by capped heptad peptidesFigure 5 Inhibition of Hendra virus and Nipah virus infection by capped heptad peptides. Vero ... moietyHypothetical models of the transmembrane (F1) glycoproteins of Hendra virus and Nipah virusFigure 1Hypothetical models of the transmembrane (F1) glycoproteins of Hendra virus and Nipah virus. The...
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báo cáo hóa học:" Evaluation of the late life disability instrument in the lifestyle interventions and independence for elders pilot (LIFE-P) study" ppt
... assesslimitations and frequency of performing life roles and activities [3]. The Lifestyle Interventions and Independence for Elders Pilot (LIFE- P) study was a single blind four-center randomized controlled ... 8:115http://www.hqlo.com/content/8/1/115Page 5 of 10RESEARC H Open Access Evaluation of the late life disability instrument in the lifestyle interventions and independence for elders pilot (LIFE- P) studyFang-Chi Hsu1*, W Jack Rejeski2, ... disability instrument in the lifestyle interventions and independence for elders pilot (LIFE- P) study. Health and Quality of Life Outcomes 2010 8:115.Submit your next manuscript to BioMed Centraland...
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báo cáo hóa học:" Validation of the Rasch-based Depression Screening in a large scale German general population sample" doc
... the manuscript. MB participated in the analysisand interpretation of the data. MW participated in the design of the studyand the statistical analysis. HG and EB participated in the design of ... the studyand coordinated the data acquisition. CN contributed to the analysis andinterpretation of the data. SG have been involved in drafting and revising the manuscript, and coordinated the ... validity basedon a representative sample of the German general population. Methods: The sample was selected with the assistance of a demographic consulting company applying a face toface in terview...
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Báo cáo hóa học: " Investigation of Nucleation Mechanism and Tapering Observed in ZnO Nanowire Growth by Carbothermal Reduction Technique" ppt
... Meyyappan5Abstract ZnO nanowire nucleation mechanism and initial stages of nanowire growth using the carbothermal reduction technique are studied confirming the involvement of the catalyst at the tip in the growth ... Reichling M: Phys Rev B 2008, 77:041405R.doi:10.1007/s11671-010-9738-3Cite this article as: Kar et al.: Investigation of Nucleation Mechanism and Tapering Observed in ZnO Nanowire Growth by Carbothermal Reduction ... such faceting is observed only in tapered nanowires and not in straightones as seen in Figure 5d, indicating such facetingmighthavesomerelationto the tapering mechanism observed in our case.Figur...
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Báo cáo hóa học: "Hypertrophy of the feet and ankles presenting in primary hypertrophic osteoarthropathy or pachydermoperiostosis: a case report" docx
... digitalclubbing (89% of cases), pachydermia: thickening and wrinkling of facial features including the forehead and the nasolabial folds, with profound hypertrophy of the eyelids (30% to 40% of cases) and ... divided into primary and secondary forms. PDP, the primary form, accounts for 3% to 5% of all cases of HOA [2]. Secondary HOA, also called pulmonary HOA,is associated with underlying cardiopulmonary ... by the Editor -in- Chief of this journal.Authors’ contributionsAll the authors of this article participated in the clinical work-up, the medicalphotography, the literature search and the writing...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngChuong 2 nhận dạng rui roTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ