báo cáo hóa học: " Hypoxia silences the neural activities in the early phase of the phrenic neurogram of eupnea in the piglet" docx
Báo cáo hóa học: " “Hypoxia-induced down-regulation of microRNA449a/b impairs control over targeted SERPINE1 (PAI-1) mRNA - a mechanism involved in SERPINE1 (PAI-1) overexpression” pptx
... transferred the finding of inverse expression of miRNA-449/SERPINE1 to an in vivo set- ting, i.e. chronic allograft remodeling in kidney trans- plants. We assumed that initial tissue damage and ongoing ... miRNA will then be incorporated into the so-called RNA-induced silencing complex (RISC), where binding of mRNA targets by miRNA takes place. Semi-complementary binding of mi...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học:" Protective CD8+ T-cell responses to cytomegalovirus driven by rAAV/GFP/IE1 loading of dendritic cells" pdf
... immediate -early 1 (IE1), expressed in HCMV. Our rAAV vector induced a strong stimulation of CTLs directed against the HCMV antigen IE1. We then investigated the efficiency of the CTLs in killing IE1 ... We used the rAAV system to induce specific CTLs against CVM antigens for the development of cytomegalovirus HCMV) gene therapy. As an extension of the versatility of...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Stem cells from umbilical cord blood do have myogenic potential, with and without differentiation induction in vitro" pdf
... their potential to restore the absent protein. Our results show CD34+ cells are able to participate in the myotube formation, resulting in the restoration of dys- trophin expression. These findings ... primary deficiency in any of these proteins induces to a secondary deficient of the entire complex, causing different types of muscular dystrophies [10,11]. Many different...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " Vaccination with a plasmid DNA encoding HER-2/ neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial" pptx
... production of Her2-pDNA vaccine To minimize the risk of malignant transformation of cells at the site of injection a kinase deficient Her2 DNA sequence (E2A) containing a m utation in codon 753 ... convert a lysine (AAA) to an alanine (GCA) resi- due in the ATP binding site [25,26] was used. From the pCMV-E2A vector the E2A insert was subcloned into pVax1 (Invitrogen, Le...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " A novel method for neck coordination exercise – a pilot study on persons with chronic non-specific neck pain" docx
... faster surfaces during the intervention period. The outcome var- iable for the improvement in performing the task, was the slope of the linear regression of the trial times on the fast- est surface ... completed, the subject was instructed to move the ball to another starting posi- tion. Light emitting diodes indicated the starting position and when the ball was...
Ngày tải lên: 19/06/2014, 08:20
Báo cáo hóa học: " Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke" ppt
... significant increase of NGF, BDNF and NT-3 transcripts and NGF proteins in both the NSC cultures and the CSF of the rats. The immunochemical staining for MHC in brain sections and the enzyme-linked immunosorbent ... staining. Immunohistochemistry staining Immunohistochemical staining of nestin and BrdU were performed to assess the property of NSC in cultures and trac...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: "Investigating the synchronization of hippocampal neural network in response to acute nicotine exposure" pdf
... absorbed rapidly by the body, either through the skin or smoking, crosses the blood-brain barrier and stimu- lates nicotinic-cholinergic receptors of the CNS, causing an increase in heart rate, blood ... Harrington Department of Bioengineering, Fulton School of Engineering ASU, Tempe AZ, USA Full list of author information is available at the end of the article Akkurt...
Ngày tải lên: 19/06/2014, 08:20
Tài liệu Báo cáo khoa học: Hypoxia reduces the expression of heme oxygenase-2 in various types of human cell lines A possible strategy for the maintenance of intracellular heme level pdf
... hypoxia. Results Effects of hypoxia on HO-1 and HO-2 expression in human cell lines We initially analyzed the effects of hypoxia on the expression of HO-1 and HO-2 in human cell lines of bone marrow origin, including ... expression in human cells under hypoxia. In the present study, we have analyzed the effect of hypoxia on the expression levels of HO-1...
Ngày tải lên: 19/02/2014, 06:20
Báo cáo khoa học: Hypoxia-driven proliferation of embryonic neural stem ⁄ progenitor cells – role of hypoxia-inducible transcription factor-1a ppt
... effect of hypoxia on NPC proliferation. In an attempt to elucidate the role of HIF-1a in the hypoxia- induced proliferative effect, we investigated the expression of HIF-1a mRNA and protein during the ... consistent with the above data. Bromodeoxyuridine incorporation assay Incorporation of Bromodeoxyuridine (BrdU) into growing (DNA-synthesizing) S phase cells is mo...
Ngày tải lên: 30/03/2014, 04:20
Báo cáo khoa học: Hypoxia induces expression of a GPI-anchorless splice variant of the prion protein potx
... panel). Detection of the splice variant of PrP mRNA in human brain To investigate whether PrPSV mRNA is expressed in human brain, we subjected total RNA of adult and fetal brains to RT-PCR analysis using the ... accumulation of an abnormal isoform of prion protein (PrP) in the brain [1]. Cellular prion protein (PrP C ) is a glycoprotein that is anchored to the cell sur...
Ngày tải lên: 30/03/2014, 04:20