Báo cáo sinh học: " Hepatitis B virus X protein interacts with β5 subunit of heterotrimeric guanine nucleotide binding protei" pptx

... domain of the HBX protein [3-6]. Another two proteins, XAP2 (X- associated protein 2) and XIP (HBX-interacting protein) were found to be negative reg- ulators of HBX. Overexpression of XAP2 abolished ... Corresponding author Abstract Background: To isolate cellular proteins interacting with hepatitis < /b> B virus X protein (HBX), from HepG2 cells infected with hepat...

Ngày tải lên: 19/06/2014, 08:20

... domain of the HBX protein [3-6]. Another two proteins, XAP2 (X- associated protein 2) and XIP (HBX-interacting protein) were found to be negative reg- ulators of HBX. Overexpression of XAP2 abolished ... two hybrid screening with HBX as bait, human guanine nucleotide binding protein β subunit 5L (GNβ5) was isolated from the cDNA library constructed in this study as a ne...

Ngày tải lên: 20/06/2014, 04:20

... infections with HBV of genotype A, B and C have been described in 0.9% of HBV infected intravenous drug users [32]. Distribution of mixed genotypes among the study groupsFigure 3 Distribution of mixed ... were HBeAg positive. Serological markers Serologic markers for HBV (hepatitis < /b> B surface antigen [HBsAg], hepatitis < /b> Be antigen [HBeAg] and antibodies to hepatiti...

Ngày tải lên: 18/06/2014, 18:20

... no proper published data are available in Sudan. Aim: The study aimed to investigate the sero-prevalance and the possible risk factors for hepatitis < /b> B virus (HBV) and hepatitis < /b> C virus (HCV) ... markers of hepatitis < /b> B virus (HBVsAg) and HCV. Results: HBVsAg was detected in 41 (5.6%) out 728 women, Anti-HCV was detected in 3 (0.6%) out of 423 women, all of...

Ngày tải lên: 18/06/2014, 18:20

... chronic hepatitis < /b> The diagnosis of HBeAg-negative chronic hepatitis < /b> B is based on the presence of HBsAg for more than 6 months, undetectable HBeAg, presence of anti-HBe, detectable serum HBV DNA exceeding ... prognosis of hepatitis < /b> B is the basis for disease management and for designing bet- ter therapeutic strategies. Hepatitis < /b> B Virus HBV belongs...

Ngày tải lên: 19/06/2014, 08:20

... Q61 - Actin binding N61 A62 - Actin binding K69 R70 F67 Actin and PIP 2 binding S71 C72 I69 Actin binding V72 V73 V70 Actin binding* I73 I74 Y71 Actin binding R74 R75 T72 Actin binding E82 D83 ... Actin binding R88 R89 L86 Actin and PIP 2 binding K90 K91 G88 Actin and PIP 2 binding T97 A95 V92 Actin binding N99 A97 P94 Actin binding V118 V116 T113 Actin binding H119...

Ngày tải lên: 18/06/2014, 18:20

... Vijaysri S, Neddermann P, Jacobs BL, Mayer BJ, Katze MG: NS5A, a nonstructural protein of hepatitis < /b> C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent ... in triplicate. A corrected binding profile was then generated by subtraction of the reference signal from the binding signal for each concentration. A 1:1...

Ngày tải lên: 20/06/2014, 01:20

... 23. Chen X, Xuan M, Wu D. Study of superinfection of HBV and HCV. Zhonghua Liu Xing Bing Xue Za Zhi 1999 ;20:141-143. 24. Zarski JP, Bohn B, Bastie A, Pawlotsky JM, Baud M, Bost-Bezeaux F, Tran ... available, little is known about this aspect. Five patients with acute HBV and HCV coinfection observed by Mimms have a lower level of HBsAg and ALT as compared with patients wi...

Ngày tải lên: 02/11/2012, 09:51

... location inside virus particles. Whether large excess of subviral particles, a unique feature of hepatitis < /b> B virus family, delays the development of anti-HBs antibody, has not been experimentally ... anti-HBs antibody is detected last. The reason for this sequence remains unknown. The HBsAg is the most abundantly expressed protein of HBV, whereas core protein has pro...

Ngày tải lên: 03/11/2012, 09:46

... infections with HBV of genotype A, B and C have been described in 0.9% of HBV infected intravenous drug users [32]. Distribution of mixed genotypes among the study groupsFigure 3 Distribution of mixed ... (sense) with a combination called mix A for geno- types A, B, and C. Mix A consisted of antisense primers BA1R (type A specific), BB1R (type B specific), and BC1R (type C...

Ngày tải lên: 20/06/2014, 01:20