Báo cáo sinh học: " Reference gene selection for quantitative real-time PCR analysis in virus infected cells: SARS corona virus, Yellow fever virus, Human Herpesvirus-6, Camelpox virus and Cytomegalovirus infections" doc

... for thevarious GO- BP categories, for example by investigating thesignature of tissue-specific expression that distinguishes,say, a ‘cell-cell adhesion’ gene from a non-cell-cell adhesion gene ... of the mouse genome. Nature 2002,420:520-573.4. The Comprehensive Knockout Mouse Project Consortium. Theknockout mouse project. Nat Genet 2004, 36:921-924.5. The European Mouse Mutagenesis ... machine-learning (pattern-recognition) algorithms were used to infer amodel to predict function for 7,387 genes labeled by Gene Ontology, using the expression measurements for the genesacross the 55 tissues....

... AccessA gene frequency model for QTL mapping using Bayesian inferenceWei He1*, Rohan L Fernando1,2*, Jack CM Dekkers1,2, Helene Gilbert3AbstractBackground: Information for mapping of ... these two models is theassumption of biallelic QTL in the gene frequency model. This assumption is often made in Maximum Like-lihood and Bayesian QTL mapping methods for mixturemodels because ... presented a gene frequency model that combines LD and cosegregation information for usein fine mapping of QTL. In this method LD informationis captured by modeling the conditional mean of the QTL given...

... use of non-additive QTL enables selection for crossbred performance based on purebred data. Compared to Crossbred selection on QTL 299Table I. Summary of notation used for the model of selection ... identification of quantitative trait loci (QTL) for many traits of interest in livestock. The strategic use of non-additive QTL in pure-line selection allows selection for crossbred performance without crossbred ... lower for ALT-STD than for PHEN for a QTL of small effect, but 12.7% greater for a QTL with large effect. Response for STD was within 3% of response to pheno-typic selection for overdominant QTL. ...

... 10.1051/gse:2004022Original article Enhanced individual selection for selecting fast growing fish: the “PROSPER” method, with application on brown trout (Salmo trutta fario)Bernard Ca,EdwigeQa,FrancineKa,Marie-GwénolaHa,MurielMa, ... first describe the theoretical background of PROSPER, then its application on one line of brown trout (Salmo trutta) over four generations. When the program started in 1986, brown trout was seen ... and the selected lineas SELg, g being the number of generations of selective breeding (or randommating for the control).Estimation of the response to selection The response to selection was...

... with an example of sire selection based on progeny test performance.discrete variable / Poisson distribution / prediction / selection response / asymmetry of response Résumé ... 1993)Summary - This paper presents a formula to predict expected response to one generation of truncation selection for a Poisson distributed trait under polygenic additive ... relies of the Poisson- lognormal model and its analysis via quasi-likelihood.The formula derived accounts for asymmetry of response. The relationship with theclassical formula...

... suicidegenes was made popular as a potential approach for treat-ing cancer. As an anti-HIV strategy this method was triedin vitro as proof-of-concept in a study that used a retrovi-rus to transduce ... sequences to a target RNA. It pairswith the target RNA forming a double-stranded RNAstructure that either blocks translation or becomes a target for degradation in the cell. Attractive targets for this ... conclusion, gene therapy is a very attractive method for treating HIV-positive patients. The approaches under-taken so far have yielded encouraging results from a safetyefficacy standpoint. Future efforts...

... fraction selected at each stage.Original article Optimum truncation points for independent culling level selection on a multivariate normal distribution, with an application to ... can be used for the computation of optimal truncation points for a broad class of objective functions with one or more constraints. Theory is developed and applications ... applications are presented for thegeneral multivariate problem considered by Smith and Quaas (1982). A practicalexample of application in the dairy cattle context is described....

... and high levels of larval density. Original article Effects of selection for early and late reproduction in low and high larval density populations of the bean weevil(Acanthoscelides ... analysis of one-generation selection for early and late reproduction in populations maintained for 10 generations at low and high levels of larval density. We have obtained ... in this paper we present the results of a study of one-generation selection for early and late reproduction in populations maintained for 10 generations at low and high...

... :Original article Reduced animal model for marker assisted selection using best linear unbiased predictionRJC Cantet*C SmithUniversity of Guelpla, Centre for Genetic ImProvement ... example is alsopresented.maker assisted selection / best linear unbiased prediction / reduced animal model /genetic marker Résumé - Un modèle animal réduit pour la sélection ... is 2r (I - r) (if marker information is available) or 1/2 (if marker infor-mation is unavailable). This occurs because, in the absence of marker information,there is...

... to selection for a ratio between 2 traits include selection for eithernumerator or denominator traits, or simultaneous selection for both traits, involvinglinear selection ... enable predicting whether selection for the ratio or for its component traits ismore effective.Original articleBidirectional mass selection for body shape in common carpY ... involvinglinear selection indices. Use of selection indices may be more effective in generatinga selection response in a ratio than direct selection for that ratio, when...