Báo cáo sinh học: " The Israeli strain IS-98-ST1 of West Nile virus as viral model for West Nile encephalitis in the Old World" pdf
Báo cáo khoa học: Cholinoceptive and cholinergic properties of cardiomyocytes involving an amplification mechanism for vagal efferent effects in sparsely innervated ventricular myocardium ppt
... cells. siRNA for ChAT To silence the effect of ChAT gene expression in HEK293 cells for the purpose of investigating the biological signifi- cance of the intracellular ACh synthesis system, we used siRNAs. ... mechanisms. Therefore, donepezil is a potent upregulator of the ACh level in the ventricular myocardium, in spite of the sparseness of cholinergic inn...
Ngày tải lên: 23/03/2014, 05:22
Tài liệu Báo cáo khoa học: Template requirements and binding of hepatitis C virus NS5B polymerase during in vitro RNA synthesis from the 3¢-end of virus minus-strand RNA docx
... made on the basis of the structure of the 5¢UTR of the plus-RNA, the structure of the 3¢-end of the minus- strand RNA being at that time unavailable. In the present study we investigated the involvement of ... Astier-Gin T (2003) An oligonucleotide complementary to the SL- B1 domain in the 3¢-end of the minus-strand RNA of the hepatitis C virus...
Ngày tải lên: 20/02/2014, 01:20
Tài liệu Báo cáo khoa học: A novel nuclear DNA helicase with high specific activity from Pisum sativum catalytically translocates in the 3¢fi5¢ direction docx
... helicase activity is defined as the amount of enzyme that unwinds 30% of the DNA helicase substrate at 37 °Cin30min(1 %in one min). For examining the effect of DNA-interacting compounds on DNA unwinding ... of all these inhibitors prior to dilution in the unwinding reaction. Under these condi- tions, there was no inhibition of the unwinding reaction (data not shown)....
Ngày tải lên: 20/02/2014, 11:20
Báo cáo khoa học: Plasmodium falciparum merozoite surface protein 1 Glycosylation and localization to low-density, detergent-resistant membranes in the parasitized erythrocyte pdf
... mAbs in the parasite pellet as well as in the supernatant. Western blotting with the anti-(C-ter) mAb showed a higher ratio of intact MSP-1 to the 19-kDa fragment in the parasite pellet than in the ... crossing the threshold is said to represent a (predicted) glycosylated site. While the GlcNAc linkages in the N-terminal half of the protein are probably e...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme docx
... expression of the liver and muscle isoforms of ovine carnitine palmitoyltransferase 1: resi- dues within the N-terminus of the muscle isoform in u- ence the kinetic properties of the enzyme. ... between the N-terminal and C-terminal regions of CPT1A [9]. In this model, Asp17 does not face the C-terminal frag- ment. A possible explanation for this is that, in t...
Ngày tải lên: 16/03/2014, 04:20
Báo cáo khoa học: Rapamycin inhibits lipopolysaccharide induction of granulocyte-colony stimulating factor and inducible nitric oxide synthase expression in macrophages by reducing the levels of octamer-binding factor-2 doc
... consider- able interest in the use of rapamycin for the treatment of in ammatory diseases. As G-CSF can function as either an anti -in ammatory or a proinflammatory cytokine, understanding the mechanism of the ... protein kinase A, pro- tein kinase C, Src-related kinases, mitogen-activated protein kinases and phosphoinositide 3-kinase (PI3K), downstream of the TLR4-s...
Ngày tải lên: 22/03/2014, 17:20
Báo cáo khóa học: Damped oscillatory hysteretic behaviour of butyrylcholinesterase with benzoylcholine as substrate potx
... to increase the rate, k, of the hysteretic transition (k is the reciprocal of s), probably by increasing the conformational plasticity of the active-site gorge. pH. The induction time of the ... a selective binding of NMIA to the E¢ form, when most of the resting enzyme was in the E form. Thus most of the enzyme would have to undergo the slow, hystereti...
Ngày tải lên: 07/03/2014, 14:20
Báo cáo khoa học: NovelN,N¢-diacyl-1,3-diaminopropyl-2-carbamoyl bivalent cationic lipids for gene delivery – synthesis,in vitro transfection activity, and physicochemical characterization docx
... TNS assay was used to ascertain the pK a values of the cationic lipids in assemblies where they were well separated from one another, precluding in uences of the hydrophobic anchors of the derivatives ... Mes) of varying pH containing TNS to give a lipid ⁄ probe molar ratio of 100 : 1. Samples were stirred for 30 min before measurement of TNS fluores- cence intensity....
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: Vibrio cholerae hemolysin Implication of amphiphilicity and lipid-induced conformational change for its pore-forming activity ppt
... monitored accumulation of the toxin at the interface of water and chloroform. The ratio of the aqueous phase concentration of the HlyA following partitioning with chloroform, c to the initial value, ... amphiphilicity was an intrinsic characteristic of the native HlyA. Amphiphilicity of the toxin was reflected in nonstoichiometric association of the protein i...
Ngày tải lên: 31/03/2014, 09:20
BÁO CÁO " SINH HỌC CỦA TÔM NƯỚC NGỌT MACROBRACHIUM IDAE (HELLER, 1862) Ở ĐẢO PHÚ QUỐC, VIỆT NAM THE BIOLOGY OF THE FRESHWATER PRAWN " doc
... implementation of projects on urbanization, upgrading infrastructure and expansion of tourist sites, and the accumulation of pesticides from agricultural activities in the island may affect the life ... Palaemonidae), reared in the laboratory. Journal of Zoology. Proceedings of the Zoological Society of London, 178: 15 – 55. Phạm Hoàng Hộ và ctv. (1985) Thực vật...
Ngày tải lên: 02/04/2014, 09:20