Báo cáo sinh học: " Genome structure and transcriptional regulation of human coronavirus NL63" docx

... analyses of knockout mice, for an important role of TRAF2, TRAF5 and TRAF6 in TNF receptor and IL1/Toll-receptor induced activation of NF-jBandJNK (c-Jun N-terminal kinase) [1,2], the role of TRAF1 and TRAF3 ... neighborhood of the respective mRNA signal. To obtain relative TRAF4 and L32 expression values the ratio between the signal intensities of bands of treated cells...

Ngày tải lên: 21/02/2014, 15:20

... wider distribution of Hc as an oxygen carrier [4–6]. The basic structure of all arthropod Hc oligomers is a hexamer of subunits [7]. This structure has been solved by crystallography [8,9] and by electron and cryoelectron ... whereas the relative size of the peaks a, b and c remain constant (Fig. 4B). The assignment of peaks b and c is based on the well-estab- lished elu...

Ngày tải lên: 23/03/2014, 13:20

... the structure of peptide cER consists of two b-turns, located at the N- and C-termini. A comparison of the b-turn structure of cER with the similar region in the crystal structure of rat and human ... ability of Jurkat cells to express CD2 was Fig. 2. Ribbon diagram of crystal structure o f CD2–CD58 complex and crystal structure of rat CD2. (A) Ribbon diagram...

Ngày tải lên: 19/02/2014, 13:20

... Fragments of HSQC and HMBC spectra of compound 1. Labels illustrate assignment of the amide linkage between the amino group of Asp and the carboxyl group of GalA residue E. Scheme 1. The structures of ... out on Sephadex G-50 (2.5 · 95 cm) and Sephadex G -15 columns (1.6 · 80 cm) in pyridinium-acetate buffer, pH 4.5 (4 mL of pyridine and 10 mL of AcOH in 1 L of water...

Ngày tải lên: 19/02/2014, 16:20

... present analysis of enzymatic properties of ChiG, or by our analysis of the ChiG and ChiC structures. Despite the deletion of the B-loop, the two putative catalytic residues Glu68 and Glu77 are ... violet) and a small, presumably amorphous, subfraction of a-chitin and b-chitin, but was not capable of degrading crystalline chitin completely. The crystal structures of chit...

Ngày tải lên: 07/03/2014, 11:20

... inducible) and TPR (tetratrico peptide repeat) domains. (B) Multiple sequence alignments of the XPCB domains of hHR23B and hHR23A with other STI1-homologous domains from yeast STI1 and DSK2, and from human ... vectors (N- and C-terminal His-tag, GST-tag, and thioredoxin-tag) and in a number of E. coli strains. It is possible that, if we expressed por- tions of the hHR2...

Ngày tải lên: 07/03/2014, 17:20

... 7. Gene structure and deduced amino acid alignment of RNase j among various species. (A) A schematic representation of the exon (rect- angles) and intron (horizontal lines) structure of the ORF ... Additionally, the burst of determina- tion of genome sequences in recent years has led to identification of homologs of many ribonucleases in a variety of diverse organisms...

Ngày tải lên: 23/03/2014, 06:20

... AdoMet-binding protein structure [14]. An antiparallel b sheet (b1, b2, b5 and b8) forms the upper part of the structure along with strands b3 and b4, which form a b meander. On the opposite side of the sheets, ... of AdoMet. A B Fig. 2. Stereoview of a superimposition of human and E. coli MS activation domains. (A) Overall structures: blue and green car- toons are hu...

Ngày tải lên: 23/03/2014, 09:21

... bone s uperimpositio n of the final 17 structures, and Fig. 1B the ribbon repre- sentation of the best representative of the ensemble for G. Rabah et al. Structure and dynamics of NSCP in solution FEBS ... quality of the restraints and to deter- mine the geometry regularity of the final structures (Table 1). More than 87% of (F, Y) angle pairs of the 17 final structures l...

Ngày tải lên: 23/03/2014, 13:20

... [21]. From the sequence alignment of human and bacterial AC- MSD and the comparison of their three-dimensional structures, the presence of the metallocofactor in the human enzyme can be reliably predicted. ... the human enzyme structure (right) was made on the base of the crystal structure analysis of P. fluorescens ACMSD (left), as described in Experimental procedures....

Ngày tải lên: 19/02/2014, 02:20