Báo cáo sinh học: "Combination therapy: the next opportunity and challenge of medicine" ppt
Báo cáo khoa học: Glutamine stimulates the gene expression and processing of sterol regulatory element binding proteins, thereby increasing the expression of their target genes docx
... after the addition of glutamine, the gene expression of the SREBP targets, such as HMG CoA synthase and the LDL receptor, was slightly increased, but then the mRNA levels of both SREBPs and their ... was calculated by the ratio of the intensity between the O-glycosylated Sp1 and the whole Sp1 signals. The ratio in the absence of both glutamine and azase...
Ngày tải lên: 28/03/2014, 22:21
Tài liệu Báo cáo khoa học: Arginine ethylester prevents thermal inactivation and aggregation of lysozyme pptx
... pH 9.2 and 7.4, respectively. The decreased pK a of amino group of ArgEE compare to Arg is related to the ethylation of the main chain of the carboxyl group. Figure 5B shows the amount of aggregation ... equation and determined the apparent T m . Results Thermal inactivation and aggregation of lysozyme in the presence of additives Figure 1 s hows the therma...
Ngày tải lên: 19/02/2014, 16:20
Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"
... contributed to the embryo, the resultant offspring will be chimeric (up to ca. 50% of animals). The ESC contribution to a mouse can high (up to ca. 80% of the cells), and will often include the germline ... variety of routes including pronuclear microinjection and SMGT [74, 75, 76]. In the context of human germline gene therapy, such vectors offer the potential a...
Ngày tải lên: 03/11/2012, 10:01
Báo cáo khoa học: "WHEN IS THE NEXT ALPAC REPORT DUE" ppt
... tations. Traditionally, the start of intensive work on machine translation is taken as being a memorand~n of Warren Weaver, then Director of the Natural Sciences Division of the Rockefeller Foundation, ... begun in the early 1960's at Grenoble and Milan reflect this, as does the work of the group sot up in Montreal in 1962. These groups based their work fro...
Ngày tải lên: 24/03/2014, 01:21
Tài liệu Báo cáo khóa học: Mutations in the hydrophobic core and in the protein–RNA interface affect the packing and stability of icosahedral viruses doc
... to the formation of cavities, one in the hydrophobic core (M88V) and the other in the protein–RNA interaction (T45S), decrease the stability of the capsid. Our findings illuminate the role of ... ð1Þ where Fi stands for the fluorescence emitted at wavenumber mi and the summation is carried out over the range of appreciable values of F. The values of center...
Ngày tải lên: 19/02/2014, 12:20
Báo cáo khoa học: Các dạng , thể thơ của câu đố người Việt pptx
... words and riddles composed in the forms and styles of poetry (Those of the metres of 2 words, 3 words, 4 words, 5 words, 7 words, six-eight-word stieh, seven-seven-six-eight word stieh, and of ... regards its form and consequently can make a comparison between riddles and other folk rhymed literature and also can understand the process of formation of our nat...
Ngày tải lên: 06/03/2014, 22:21
Báo cáo khoa học: Exosites mediate the anti-inflammatory effects of a multifunctional serpin from the saliva of the tick Ixodes ricinus potx
... helices. The mean surface accessibility of the predicted epitopes on the Iris 3D structures was calculated by averaging the accessible surface area of the peptide residues using the Shrake and Rupley ... epitopes and recep- tor-binding domain. The first column indicates the amino acid positions in the protein sequence. Angle, the calculated angle between the helix...
Ngày tải lên: 07/03/2014, 01:20
Báo cáo Y học: ORF6 from the clavulanic acid gene cluster of Streptomyces clavuligerus has ornithine acetyltransferase activity potx
... responsible for the biosynthesis of other clavams [13,14]. Thus, only functions for the gene products of orfs2–5 in the early stages of the pathway and the final stage (orf 9) of the clavulanic ... this, extension of the time the ORF6 protein was heated with SDS before electrophoresis resulted in apparent conversion of the lower b subunit band to the upper ban...
Ngày tải lên: 08/03/2014, 22:20
Báo cáo khoa học: Residues affecting the chloride regulation and substrate selectivity of the angiotensin-converting enzymes (ACE and ACE2) identified by site-directed mutagenesis pot
... mutagenesis of CL1 and CL2 site residues of tACE and ACE2 The residues surrounding the chloride ion at the CL1 and CL2 sites of tACE and ACE2 are shown in Fig. 1. In tACE, the residues that coordinate the ... that in the absence of NaCl and 3.2- fold less than that at 100 mm NaCl. Effects of CL1 and CL2 site mutations on the chloride sensitivity of tACE...
Ngày tải lên: 16/03/2014, 04:20
Báo cáo khoa học: Phosphorylation modulates the local conformation and self-aggregation ability of a peptide from the fourth tau microtubule-binding repeat pdf
... pK a1 and pK a2 . The pK a value is deter- mined from a fit of the phosphorus chemical shifts of the without ionic, monoionic and diionic forms of the phosphate group as a function of pH [33,34]. The phosphorus ... at neutral pH, affects the electrostatic potential and quite often the conformation of the modified protein. Even in the absence of rearrangement,...
Ngày tải lên: 16/03/2014, 05:20