Báo cáo sinh học: "Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication" pot
Tài liệu Báo cáo khoa học: Molecular and cellular specificity of post-translational aminoacyl isomerization in the crustacean hyperglycaemic hormone family docx
... axon terminal in the sinus gland, as a result of late and progressive isomerization of the Phe3 of the CHH during the migration of the secretion vesicles along the axonal tract [39,41]. The immunohistochemical ... microscopy study of the neuronal endings in the sinus gland to determine the subcellular localization of the different epimers. Taken togethe...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: Molecular and biochemical characterization ofD-phosphoglycerate dehydrogenase fromEntamoeba histolytica A unique enteric protozoan parasite that possesses both phosphorylated and nonphosphorylated serine metabolic pathways docx
... at the nucleotide binding domains and the regulatory domain, indicating the importance of these domains for the tetramerization of the enzyme [18]. It was shown that serine binding induces a conformational ... approximately 90% when two of the four serine binding sites of the PGDH tetramer were bound to serine [19], indicating that the binding of a single serine at...
Ngày tải lên: 19/02/2014, 13:20
Tài liệu Báo cáo khoa học: Molecular and functional characterization of adenylate kinase 2 gene from Leishmania donovani pdf
... conformation to the protein during binding of the substrate is shown in the top-most portion of the protein. ATP may bind to the glycine loop on the left flap portion (Fig. 8B) and AMP may bind to the AMP ... the enzyme. The three different views were obtained by simple rotation of the same model. The flexible LID domain appears at top of the three figures, NMP...
Ngày tải lên: 21/02/2014, 00:20
Báo cáo khoa học: Molecular and functional characterization of novel CRFR1 isoforms from the skin pptx
... cyclase with the exception of an artificial isoform (CRFR1h2) with the insertion of 37 amino acids between the ligand binding domain and the first extracellular loop that was capable of producing detectable ... cAMP production stimulated by urocortin. The artificial isoform (CRFR1h2) with the insertion of 37 amino acids between ligand binding domain and the first extrace...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: Molecular and functional characterization of a novel splice variant of ANKHD1 that lacks the KH domain and its role in cell survival and apoptosis docx
... protein containing a single ankyrin repeat that interacts with HIV-1 viral protein R (Vpr) and we designated this protein as Vpr-binding ankyrin repeat protein (VBARP). This interaction was further ... con- firmed that the cytoplasmic distribution of VBARP is independent of the cycling stage of the cells. Identification of biological function( s) of VBARP using a siRNA assa...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: Functions and cellular localization of cysteine desulfurase and selenocysteine lyase in Trypanosoma brucei pot
... dilution. Induction of dou- ble-stranded RNA synthesis upon the addition of tet- racycline indeed resulted in efficient elimination of the SCL mRNA in two selected clones within 24 h of induction ... another function of this protein. The absence of Nfs disrupts Fe–S cluster assembly, monitored by the decrease in the activities of Fe–S cluster-containing proteins...
Ngày tải lên: 22/03/2014, 21:20
Báo cáo khoa học: Molecular and genetic characterization of osmosensing and signal transduction in the nematode Caenorhabditis elegans docx
... ions in the cyto- plasm and functions as a chemical chaper- one that aids in the refolding of misfolded proteins. Loss of function of protein homeo- stasis genes also causes accumulation of damaged ... responses. Extracellular solute and water balance in animals is maintained by behavioral responses and by the func- tion of the kidney and kidney-like organs...
Ngày tải lên: 30/03/2014, 03:20
Báo cáo Y học: Molecular and biochemical characteristics of a gene encoding an alcohol acyl-transferase involved in the generation of aroma volatile esters during melon ripening pptx
... detected in fruit (Table 1), indicating that the availability of some acyl donors is a limiting factor in vivo. Table 2 shows some kinetic properties of the recombinant CM-AAT1 protein for some of the ... transformed following the instructions pro- vided by the manufacturer (Invitrogen). The strain har- bouring the correct construction was incubated in selecting liqu...
Ngày tải lên: 31/03/2014, 21:21
Báo cáo y học: "PKC and PKA Phosphorylation Affect the Subcellular Localization of Claudin-1 in Melanoma Cells"
... (CLDN1-NLS), there is increased expression of claudin-1 in the nucleus, but there are still large amounts of claudin-1 in the cytoplasm as well. B) All of the claudin-1 in the nucleus can be shuttled into ... expression of claudin-1 in the cytoplasm, with some nuclear expression of claudin-1. B) Treatment of these cells with PKA inhibitor results in nuclear tr...
Ngày tải lên: 03/11/2012, 11:17
Báo cáo khoa học: Concepts and tools to exploit the potential of bacterial inclusion bodies in protein science and biotechnology pdf
... a-helices of the N-terminal 185 residues of the functional domain of the HA2 subunit of the in uenza virus hemagglutinin protein and to detect conformational heterogeneity of the protein within IBs [65]. ... pathways of protein folding are reflected in the formation of IBs and in their structure. Study- ing protein aggregates can therefore provide a first glim...
Ngày tải lên: 06/03/2014, 00:20