... 100% abundance. The implications of a noncooperative metal-binding mechanism are that the partially metallated and metal-free species are stable intermediates, and thus may have a poten- tial role ... nonessential metal ions in vivo and in vitro strongly suggests a role in metal ion storage, metabolism and trafficking of Cu and Zn, as well as sequestration of Cd and Hg;...
Ngày tải lên: 19/02/2014, 00:20
... eIF 2a- kinases is a general phe- nomenon, we also investigated the modulation of eIF 2a phosphorylation in conditions activating GCN2. As expected, amino acid starvation (deprivation of four amino acids) ... Nck strongly impair the phosphorylation of eIF2aSer51, attenuation of translation and polysomal dissociation that nor- mally occur in response to pharmacological induction...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo Y học: The human b-globin locus control region A center of attraction potx
... and binds to DNA as a heterodimer usually composed of USF1 and USF2. USF has been implicated in the r egulation of m any genes and normally acts as a transcriptional activator. However, it has ... replicating, and remains in a DNase I-resistant and inaccessible configuration. However, recent analysis of the consequence of a targeted deletion of the LCR demonstrates...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo khoa học: Natural-abundance isotope ratio mass spectrometry as a means of evaluating carbon redistribution during glucose–citrate cofermentation by Lactococcus lactis potx
... irect decarboxylation o f a- acetolactate, a conclusion confirmed by the absence of any accumulation of butan-2,3-diol. Both products accu- mulate in strains lacking a- acetolactate decarboxylase [22,33,34] ... [11]. esoculg 5.0 etartic etavuryp etatcal α etatcaloteca- etamrof A oC-lyteca HDAN D AN + HDAN DAN + nioteca l y tecaid P-lyteca eta teca HDAN DAN + PDA PTA HDAN DAN + PTA PD...
Ngày tải lên: 30/03/2014, 15:20
Tài liệu Báo cáo khoa học: The tungsten-containing formate dehydrogenase from Methylobacterium extorquens AM1: Purification and properties docx
... Titrisol iron solution (Merck) as a standard. Acid-labile sulfur was determined as methy- lene blue [28] using Na 2 S as standard. Covalently and noncovalently bound flavins were determined as described [29]. ... via four chromatographic steps at 4 °C under oxic conditions. All chromatographic materials were from Amersham Pharmacia Biotech. The soluble fraction of the cell extract (41 mL...
Ngày tải lên: 20/02/2014, 23:20
Báo cáo khoa học: "Question Answering as Question-Biased Term Extraction: A New Approach toward Multilingual QA" doc
... Hirotoshi Taira, Yutaka Sasaki, and Eisaku Maeda: Directed Acyclic Graph Kernel, Proc. of ACL 2003 Workshop on Multilingual Summarization and Question Answering - Machine Learning and Beyond, pp. ... evaluation consists of exact matching and par- tial matching. Partial matching is useful for ab- sorbing the variation in extraction range. A partial match is judged correct if a...
Ngày tải lên: 08/03/2014, 04:22
Báo cáo khoa học: Mitochondrial biogenesis in mtDNA-depleted cells involves a Ca2+-dependent pathway and a reduced mitochondrial protein import pdf
... 5¢-TGCG CTCCATGGCATCT-3¢, antisense 5¢-CTTCTTTGCAGC CAGCATGAT-3¢; b-ATPase sense 5¢-CCATCCTGGGTA TGGATGAACT-3¢, antisense 5¢-GGCTGAGACAAGAA ACGCTGTAT-3¢, TBP sense 5¢-CCTCACAGGTCAAAG GTTTACAGTAC-3¢, antisense ... 296– 302. 96 Davis AF, Ropp PA, Clayton DA & Copeland WC (1996) Mitochondrial DNA polymerase gamma is expressed and translated in the absence of mitochon- drial DNA maintenan...
Ngày tải lên: 23/03/2014, 15:21
Tài liệu Freedom of Expression on the Internet - A study of legal provisions and practices related to freedom of expression, the free flow of information and media pluralism on the Internet in OSCE participating States ppt
... harmonization of laws and approaches at the international level. Regarding speech- and content-related laws and legal measures, any restriction must meet the strict criteria under international and ... types of content deemed to be illegal by state authorities. Based on the limited effectiveness of state laws, and lack of harmonization at the international level...
Ngày tải lên: 18/02/2014, 00:20
Báo cáo khoa học: Acute intermittent porphyria – impact of mutations found in the hydroxymethylbilane synthase gene on biochemical and enzymatic protein properties pdf
... the principals of the Declaration of Helsinki. Isolation and amplification of DNA Genomic DNA was extracted from peripheral blood leuko- cytes anticoagulated with EDTA according to a standard protocol. ... expression of mutations in the HMBS gene can provide valuable information with respect to the interpretation of clinical, biochemical and genetic data and establishing a...
Ngày tải lên: 23/03/2014, 04:21