Báo cáo sinh học: " Spectratyping analysis of the islet-reactive T cell repertoire in diabetic NOD Igμnull mice after polyclonal B cell reconstitution" potx
... post- reconstitution. This allowed us to identify the < /b> expanding TCR repertoire < /b> infiltrating the < /b> islets of < /b> NOD.< /b> Igμ null mice < /b> that are dependent on B cells. We observed that without B cell < /b> reconstitution, ... capsule of < /b> diabetic < /b> B cell < /b> reconstitu ted NOD.< /b> Igμ null mice < /b> were rejected very fast (within 4 d...
Ngày tải lên: 18/06/2014, 19:20
... post- reconstitution. This allowed us to identify the < /b> expanding TCR repertoire < /b> infiltrating the < /b> islets of < /b> NOD.< /b> Igμ null mice < /b> that are dependent on B cells. We observed that without B cell < /b> reconstitution, ... implants were removed for spectratyping < /b> analysis < /b> of < /b> TCR repertoire < /b> of < /b> inf iltrating T < /b> cells...
Ngày tải lên: 20/06/2014, 04:20
... E120A mutant and, to a lesser extent the < /b> E35A mutant, none of < /b> the < /b> other mutants were capable of < /b> complimenting the < /b> conditional mutant virus grown in < /b> the < /b> absence of < /b> TET. These results are in < /b> accordance ... inhib- ited G1L processing. This may be indicative of < /b> either the < /b> loss of < /b> a zinc ion, which would render a m...
Ngày tải lên: 19/06/2014, 08:20
Báo cáo khoa học: Epitope analysis of the rat dipeptidyl peptidase IV monoclonal antibody 6A3 that blocks pericellular fibronectin-mediated cancer cell adhesion pot
... examine the < /b> stability of < /b> the < /b> 6A3 epitope. Epitope mapping of < /b> 6A3 may be the < /b> most direct approach for answering the < /b> above questions [21]. In < /b> the < /b> present study, we first show that the < /b> inhibi- tory ... solu- ble rDPP IV lost the < /b> ability to bind to immobilized MTF7 cell < /b> surfaces to the < /b> same degree that polyclonal...
Ngày tải lên: 29/03/2014, 22:21
Báo cáo Y học: Structural analysis of the lipopolysaccharide from nontypeable Haemophilus influenzae strain 1003 potx
... to be present i n the < /b> LPS of < /b> all of < /b> these strains ( data not shown). S tructural a nalyses have shown that PCho can be linked to terminal hexose residues attached to either one of < /b> the < /b> three inner-core heptose ... erely the < /b> members of < /b> the < /b> Finnish Otitis Media Study Grou p at the < /b> National P ublic Health Institu te in < /b> Finland...
Ngày tải lên: 31/03/2014, 21:21
Tài liệu Báo cáo khoa học: Quantitative analysis of the experimental O–J–I–P chlorophyll fluorescence induction kinetics Apparent activation energy and origin of each kinetic step Steve Boisvert, David Joly and Robert Carpentier doc
... rate constant of < /b> the < /b> J–I phase compared to the < /b> amplitudes and rate constants of < /b> the < /b> two other phases. The < /b> above should be gov- erned by the < /b> balance between the < /b> rate of < /b> reduction and oxidation of < /b> ... demonstrating that the < /b> J–I rise is not directly related to the < /b> reduction of < /b> the < /b> PQ pool. A furthe...
Ngày tải lên: 19/02/2014, 05:20
Tài liệu Báo cáo khoa học: Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation ppt
... (one of < /b> 5¢-AAGCT TCACCATGTACCCTGCCCACATGTACCAAGTG TAC-3¢,5¢-AAGCTTCACCATGCCGCACCGG CTC ATCGAGAAAAAGAG-3¢,5¢-AAGCTTCACCATG GCAGTGGTTCTTGAACTTACCTTGAAGC-3¢ or 5¢-AAGCTTCACCATGATTGCCCTGCAGAGTGG TTTACAAGCTG-3¢) ... region, including the < /b> PAS -B domain of < /b> BMAL1, is required for the < /b> binding to DEC1, Fig. 4. Identification of < /b> the < /b> domain of < /b> D EC1 that i...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: Fluorescence analysis of the Hansenula polymorpha peroxisomal targeting signal-1 receptor, Pex5p pdf
... due to FRET from certain Trp residues in < /b> the < /b> C-terminus of < /b> HpPex5p to the < /b> dansyl cap in < /b> the < /b> PTS1 peptides, the < /b> distance between the < /b> dansyl cap in < /b> L2 and the < /b> three tryptophan residues in < /b> the < /b> model ... cytosolic ribosomes. In < /b> order to ensure that these proteins reach the < /b> correct destination in <...
Ngày tải lên: 21/02/2014, 00:20
Báo cáo khoa học: Structure analysis of the flavoredoxin from Desulfovibrio vulgaris Miyazaki F reveals key residues that discriminate the functions and properties of the flavin reductase family pdf
... retention time of < /b> the < /b> obtained prosthetic group was compared with those of < /b> flavin derivatives. The < /b> retention time of < /b> the < /b> prosthetic group bound to recom- binant flavoredoxin was identical to that of < /b> FMN (Fig. ... [5,6]. The < /b> crystal structure of < /b> FeR has been determined with and without NADP + [6]. These authors were unsuccessful in...
Ngày tải lên: 07/03/2014, 02:20
Báo cáo khoa học: Interaction analysis of the heterotrimer formed by the phosphatase 2A catalytic subunit, a4 and the mammalian ortholog of yeast Tip41 (TIPRL) ppt
... 7. The < /b> interaction of < /b> PP2Ac with the < /b> regulatory B sub- unit requires the < /b> extreme C-terminal region of < /b> the < /b> cat- alytic subunit [29] and the < /b> interaction site for TIPRL was mapped to the < /b> C-terminal ... to the < /b> C-terminus, respec- tively. The < /b> interaction between TIPRL and the < /b> catalytic subunit of < /b> type 2A phosph...
Ngày tải lên: 07/03/2014, 05:20