... factor that transactivates the expression of death-activating proteins, such as Fas ligand (FasL) and Bim [12]. Phosphorylation of FKHRL1 at Thr32, Ser253 and Ser315 prevents translocation of ... Ohmichi M, Hayasaka T, Mabuchi S, Saitoh M, Kawagoe J, Takahashi K, Igarashi H, Du B, Doshida M, Mirei IG, Motoyama T, Tasaka K, Kurachi H: Inhibition of Phosphatidylinositol 3-Kinase Increases Efficacy ... antibody, the percentage of apop-totic cells was restored to levels of observed with cisplatintreatment alone. Apoptosis was also assessed under thesame conditions by TUNEL assay. OvCa cell lines...