Báo cáo sinh học: "The combined transduction of copper, zincsuperoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury" ppt

... dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury. Journal of Translational Medicine 2011 9:73. Huang et al. Journal of ... min followed by PI for 15 min. The apoptosis rate was evaluated by Flow cytometry. Transduction of PEP-1-SOD1 and/ or PEP-1-CAT in rat myocardium and isch...

Ngày tải lên: 18/06/2014, 19:20

... (1991 to 2005) Michel D Landry* 1,2 , Thomas C Ricketts 2,3 and Molly C Verrier 1 Address: 1 Department of Physical Therapy, Faculty of Medicine, University of Toronto, Canada, 2 Department of ... "Appropriate planning and manage- ment of HHR are key to developing a health-care work- force that has the right number and mix of health professionals to serve Canad...

Ngày tải lên: 18/06/2014, 17:20

... Mozambique, which needs to provide ART to about 200,000 patients, would require 200–400 doctors from its' total stock of 514, and 400–1400 nurses from its total stock of 3947. Other estimates of the workforce ... adoption of a low-resource model of ART provision, underscored by task shifting and the use of clinical officers and nurses to diagnose and treat...

Ngày tải lên: 18/06/2014, 17:20

... replicase gene of viruses in 7 of the 8 genera of the Tombusviridae [24]. This division of the rep- licase of the Tombusviridae by a termination codon is thought to be part of a translational read though ... of 774 nt followed by two predicted ORFs of 4842 nt (ORF 1, nt position 775 to 5616) and 2589 nt (ORF 2, nt posi- tion 5914 to 8502) separated by an IGR of...

Ngày tải lên: 18/06/2014, 18:20

... oncogenes HPV16 E5, E6 and E7 and different apoptotic pathways have already been identified [9]. E6 and E7 modulate apoptosis by binding and inactivating p53 and the product of tumour suppressor ... [10,11], thereby deregu- lating the cell cycle. E5 impairs ligand -mediated apoptosis by reducing the amount of surface CD95 proteins or inhibiting the formation of the DISC c...

Ngày tải lên: 18/06/2014, 18:20

... dropped down to 1% of the wt SD-1 IRES in mutant M1, could be restored in compensatory mutant M2 to 78% of wt level. In summary, the results from mutational analysis of stem 1 and stem 2 of the putative ... by the moncistronic constructs were taken into account to calculate the effect of the inclusion of coding region on IRES mediated translation. The AUG context at...

Ngày tải lên: 18/06/2014, 18:20

... production of a va riety of cytokines and chemokines, including IL-8 from macrophages. The IL-21 receptor includes a comm on IL-2R g-chain and signaling is meditated by JAK 1,3 and STAT1, STAT3, and ... involved in cytokines binding to a receptor, causing receptor dimerization and signal transduction through receptor kinases, resulting in activation and translocation...

Ngày tải lên: 18/06/2014, 19:20

... SC: Expression of beta-F1- ATPase and mitochondrial transcription factor A and the change in mitochondrial DNA content in colorectal cancer: clinical data analysis and evidence from an in vitro ... (annexin-positive) cells and the upper right and left quadrants corresponds to dead (PI positive) cells. Histograms shown are the means ± SEM of the percentage of apoptotic (ann...

Ngày tải lên: 18/06/2014, 19:20

... NBD2B (792 lm), and NBD2A (529 lm). The different activities of NBD2A and NBD2B could result from an inhibitory effect of the C-terminal 42 amino acids of NBD2B or a stimulatory effect of the equivalent ... l M,aV max of 2.52 nmol P i ÆminÆmg )1 and an offset of 0.1 nmol P i ÆminÆmg )1 for SUR2A, and a K m of 41 lM,aV max of 0.73nmol P i ÆminÆmg )1 and an offset o...

Ngày tải lên: 06/03/2014, 11:20