báo cáo hóa học: " Development and psychometric assessment of the COPD and Asthma Sleep Impact Scale (CASIS)" pdf

... measures and extend our understanding of the impact of respiratory disease symptoms on sleep impact and quality. Given the prevalence of sleep problems in patients with asthma or COPD and the absence ... Development and validation of the Asthma Life Impact Scale [ALIS], submitted) during the baseline visit or survey. COPD and Asthma Sleep...

Ngày tải lên: 18/06/2014, 19:20

... modifier of the extent of the hypertrophy in our pop- ulation, in patients with and without sarcomeric muta- tions. The role of the AT 1R SNP as a modifier of the phenotype was also supported by the ... polymorphisms at these genes. We also determined the effect of these gene poly- morphisms on onset age and the extent of the hypertro- phy. Methods Patients...

Ngày tải lên: 18/06/2014, 16:20

... wrote the draft of the manuscript. HT participated in the design of the study, and carried out the clinical research. AK, AI, NO, YI participated in the conduct and data management of the clinical ... ELISPOT and MHC-Dextramer assay ELISPOT and the MHC-Dextramer assay are shown in the left (a, e, i, c, g and k) and right (b, f, j, d, h and l) side of ea...

Ngày tải lên: 18/06/2014, 16:20

... complete the scale. Conclusion: After the cultural adaptation process, a Spanish version of the GAD-7 scale was obtained. The validity of its content and the relevance and adequacy of items in the ... administered to the sample of patients and controls together with three other instruments: the Hamilton Anxiety Scale (HAM-A) [14], the Hospit al Anxiety a...

Ngày tải lên: 18/06/2014, 19:20

... feature of the a receptor components belonging to the IL-6 family is their ability t o promote the action of their ligands. These have been described in detail for IL-6/IL-6R, CNTF/CNTFR and IL-11/IL-11R [23,36,37]. ... esidues 1–286 of CNTFR were modeled by homology with gp130 (PDB accession numbers: 1BQU for the cytokine-binding domain of gp130 and 1I1R for the Ig-like...

Ngày tải lên: 08/03/2014, 10:20

... constituted of two-thirds of the UK clinical trial subjects. The scale structure was then validated in the remaining one-third of the "UK validation population", to assess the robustness of the ... between the severity of each reaction reported for 8 days after the injection using the verbal rating scale, and the respective items of the "b...

Ngày tải lên: 18/06/2014, 19:20

... suggested by the EFA. The Brazilian dataset showed coefficients of .863 for the Subscale I (and .845 for the International dataset), .804 for the Subscale II (.822 for the International sam- ple) and ... studies reliably. Another relevant issue regarding the findings of the AAQ validation is the construct similarity between the interna- tional sample and the Bra...

Ngày tải lên: 18/06/2014, 22:20

... cells [16-18]. The activities of IL21 have been shown to be highly dependent on the lineage of the target cell, the activation state of the target cell and the presence of other co-stimulators and immune ... here, analyzed the data and co-wrote the manuscript. SJ and AAW performed all the pilot studies in humans and monkeys that identified the candidate b...

Ngày tải lên: 18/06/2014, 16:20

... ISH and the expression levels of IGF2-P4 and H19 transcripts were determined by the intensity of the hybridization signal and by the quantity of the stained cells. Table 3 shows that out of 28 ... early studies of our group and others, the transcriptional regulatory sequences of the H19 and IGF2 genes emerged as candidates for cancer targe ted therapy. H19...

Ngày tải lên: 18/06/2014, 16:20

... and the development of caregiver stress and burden [5]. Families often report that behavio- ral disturbances are the primary source of stress and the primary cause for institutionalization of their ... of caregiving (p  0.05)). In con- trast, there were few associations of duration of being a caregiver and caregiver quality -of- life scores. Non-white ethnicity o...

Ngày tải lên: 18/06/2014, 18:20