... useful platform for the building of functional intrabody libraries [4,29]. The initial aim of this study was to investigate whe- ther the modification of the half -life of an active intra- body could ... perform well when expressed intracellularly. This may be due to the redu- cing conditions existing in cell compartments, which may prevent the formation of intradoma...
Ngày tải lên: 19/02/2014, 18:20
... transport chain would nor- malize the pathways involved in the development of the oxidative stress (68). If our findings are proven by further studies in- volving a larger number of patients, ... scavenging already formed oxidants and may be considered symptomatic instead of a causal treatment for oxidative stress (67). Inter- ruption of the overproduction of s...
Ngày tải lên: 26/10/2012, 09:39
Báo cáo y học: "Godoy & Godoy technique in the treatment of lymphedema for under-privileged populations."
... produce their own compression stockings, sleeves or gloves. The use of these compression mechanisms gives a certain independence of patients allowing them to return to their daily activities. Interdisciplinary ... depending on several factors such as, for example, the weight and the fitness of the patient and the duration of exercises. Compression mechanism One...
Ngày tải lên: 26/10/2012, 09:39
Báo cáo y học: " Vacuum-assisted closure in the treatment of early hip joint infection"
... re-established. The increase of the oxygen gradient facilitates the transportation of toxins and inhibitors inducing thereby the wound healing [16]. As a result of the increased angiogenesis, the local ... not often used in orthopaedic surgery. In this study, we report our experience on the management of bacterial infections and/or draining sinus of the hip...
Ngày tải lên: 26/10/2012, 09:53
Báo cáo y học: " Two-stage procedure in the treatment of late chronic hip infections spacer"
... however; is influenced by the ratio in which the antibiotics are mixed into the cement and therefore, the total dose of antibiotics should not exceed 10% of the weight of the cement in order ... spacers formed in the operating room have the advantage of adjustable antibiotic dosing. Disadvantages of such spacers in- clude additional time to construct th...
Ngày tải lên: 26/10/2012, 09:53
Tài liệu Báo cáo khoa học: An alternative isomerohydrolase in the retinal Muller cells of a cone-dominant species doc
... RPE65c in the inner retina, including Mu ¨ ller cells, but not in the RPE. Furthermore, double-immuno- staining of dissociated retinal cells using antibodies for RPE65c and gluta- mine synthetase (a ... containing atRE in the presence of 1m M bipyridine (B) and liposomes containing atRE, in the presence of 1 m M bipyridine and 6 mM FeSO 4 (C). The generated retinoids...
Ngày tải lên: 14/02/2014, 14:20
Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx
... is known to bind a Zn 2+ ion, rendering stability to the adjacent PH domain. The substitution of conserved Zn 2+ -interacting amino acids results in the formation of a highly unstable protein, which ... lymphoproliferative dis- ease. Arginine 335 is found in the ‘BG loop’ not involved in phosphotyrosine binding and mutation to tryptophan most probably causes instability of...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Báo cáo khoa học: Osmosensing and signaling in the regulation of mammalian cell function docx
... integrin-dependent cell volume sensing and signaling integrates into the overall context of insulin signaling. Similarly, sensing of glutamine-induced hepatocyte swelling by integrins feeds into ... hepatocyte swelling [12,13], insu- lin-induced hepatocyte swelling is registrated by the integrin system, leading to a Src-dependent activation of the p38-type MAPK and thereby inhibit...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: An intermediate step in the evolution of ATPases – a hybrid F0–V0 rotor in a bacterial Na+ F1F0 ATP synthase pdf
... of the ion-binding site. Therefore, the c ring of A. woodii has only 10 membrane-buried negative charges that are essential for binding the ion and also for the rotational mechanism of the ring. ... to the other two, forming the same pattern as in the AFM surface representation of Fig. 2A. By comparison with the 3D structure of the I. tartaricus c ring [24]...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: Bone morphogenetic proteins in the early development of zebrafish pptx
... synthesized in the Spemann organizer, namely Follistatin, Chordin and Noggin [12]. These proteins are antagonists of BMP and other members of the TGF-b family, binding to and inhibit- ing these ... embryos, the din mutant is not rescued. Expression of chordin is induced by Sizzled in embryos with Chordin, but not in the absence of Chordin. These results indicate that Cho...
Ngày tải lên: 19/02/2014, 00:20