Báo cáo sinh học: " Genetic incorporation of the protein transduction domain of Tat into Ad5 fiber enhances gene transfer efficacy" docx

... 11 (page number not for citation purposes) Virology Journal Open Access Research Genetic incorporation of the protein transduction domain of Tat into Ad5 fiber enhances gene transfer efficacy Tie ... re-targeting Ad5 vector via the PTD tat motif would improve the efficacy of Ad5- mediated gene delivery. Results: In this study, we genetically incorpo...

Ngày tải lên: 18/06/2014, 18:20

... with a distinctively shorter N- terminus than the wild-type form [6]. Protein 3a is one of the SARS-CoV accessory proteins and the expression of the 3a protein has been demonstrated during both in ... properties) of 3a may be involved in modulating the trafficking properties of the spike protein [14]. Our results showed that the viruses in some of the patients...

Ngày tải lên: 19/06/2014, 08:20

... built from the X-ray structure of the C-terminal domain of Ure2p and integrates the finding that the N-terminal domain of Ure2p is flexible. An enlargement of the region of Ure2p involved in the interaction ... conformational changes modulate the assembly of Ure2p into fibrils and further highlight the involvement of the C-terminal domain of Ure2p in th...

Ngày tải lên: 15/03/2014, 00:20

... with an insertion of two amino Alignment of the deduced amino acid sequences of the immuno-dominant residues of the VP1 surface protein, including the GH-loopFigure 5 Alignment of the deduced amino ... 3 Bayesian phylogenetic analysis of the genome regions coding for the struc- tural proteins of the A/IRN/2005 sublineage and related published sequences. Represe...

Ngày tải lên: 18/06/2014, 18:20

... that of M96026 and its mother A94040 Our data demonstrates that the env gene of SRV-2 is very stable suggesting a remarkable adaptation of the virus to its host. Within the five isolates of SRV-2E ... http://www.virologyj.com/content/3/1/11 Page 7 of 15 (page number not for citation purposes) Multiple alignment of the complete env sequences of representative prototypes...

Ngày tải lên: 19/06/2014, 08:20

... SSAT. The apparent synergism between the polymorphism of the ODC gene and the use of aspirin was proposed to be a combined result of an inhibition of polyamine biosynthesis and an activation of their ... within). The spontaneous Hyp mutation affects only the Phex gene while in the X-ray-induced Gy mutation, the deletion extends upstream of the Phex gene and...

Ngày tải lên: 30/03/2014, 13:20

... only 8% of the health workers, while the quintile with the most health workers has 46% of the workers. The value of the Gini index is 0.229. Part of the inequality in the distribution of health ... care needs (i.e. the level of population). By com- bining the use of concentration curves for these alterna- tive measures of need with the Lorenz curve of...

Ngày tải lên: 18/06/2014, 17:20

... countries". Based on the advice of one of the authors (PF), an expert in the field of maternal health and EmOC, the search strat- egy was supplemented by a systematic review of the table of contents of specific ... greatest part of that delay was attributed to the purchase of therapeutic material by patients and their families [48]. The overall evaluation o...

Ngày tải lên: 18/06/2014, 17:20

... clear indication of the inade- quacy of adopting a strategy of training and employing mid-level cadres in the absence of strategies to strengthen and improve other aspects of the health environment ... number of strongly loading items [26,27]. Rotation of the extracted compo- nents produced a more interpretable solution than the unrotated solution. Figure 1 shows the...

Ngày tải lên: 18/06/2014, 17:20

... we assessed the degree of variation in the PA workforce distri- bution across the states. Furthermore, we examined the ratio of PAs to population by state. The analysis was sup- plemented with data on the ... 0.5 by 2007. Another remarkable change is that the rates of PAs to population and the average wages of PAs vary greatly across the 50 states and District of C...

Ngày tải lên: 18/06/2014, 17:20