Báo cáo sinh học: " The state of the art of adeno-associated virus-based vectors in gene therapy" ppt
Báo cáo sinh học: " The state of the art of adeno-associated virus-based vectors in gene therapy" ppt
... rAAV are increasingly becoming the vector of choice for a wide range of gene therapy approaches. This review will originally highlight the state of the art of AAV-based vector studies and the advances ... pioneering work on the successful cloning of AAV establishing the foundation of recombinant AAV vectors capable of expressing foreign genes in mammalian c...
Ngày tải lên: 18/06/2014, 18:20
báo cáo sinh học:" Is satisfaction a direct predictor of nursing turnover? Modelling the relationship between satisfaction, expressed intention and behaviour in a longitudinal cohort study" pdf
... change the overall findings. A finding that was consistent across all models was the increasing strength of relationships the nearer the expressed intentions were to the time-point of interest. Only ... and the interpreted the findings. SR made a major contribution to the conception of the study, the design, data collection and interpretation. PG provided intellec- t...
Ngày tải lên: 18/06/2014, 17:20
báo cáo sinh học:" Human resources and the quality of emergency obstetric care in developing countries: a systematic review of the literature" potx
... inad- equacy of human resources (HR) in developing countries. In the health sector in general, and in maternal health in particular, health care professionals are at the heart of the success of EmOC interventions ... that the failure of the policy regarding traditional birth attendants is due mainly to the lack of technical legitimacy in their training, the...
Ngày tải lên: 18/06/2014, 17:20
báo cáo sinh học:" Measuring and managing the work environment of the mid-level provider – the neglected human resource" pdf
... gives a clear indication of the inade- quacy of adopting a strategy of training and employing mid-level cadres in the absence of strategies to strengthen and improve other aspects of the health ... each of the three geographical regions in Malawi. A total of 34 health facilities from the three districts were included in the study. All staff in each of the...
Ngày tải lên: 18/06/2014, 17:20
báo cáo sinh học:" Experience with a "social model" of capacity building: the Peoples-uni" ppt
... for, and maybe methods of, co-authoring of course modules. ICT development The use of e-learning through the Internet is the basis of the ability of Peoples-uni to assemble an international faculty ... the goals of their institu- tions or governments. These teachers are committed to meeting capacity-building goals in resource-poor settings, but their employers insist th...
Ngày tải lên: 18/06/2014, 17:20
Báo cáo sinh học: " Epidemics to eradication: the modern history of poliomyelitis" docx
... mapping to the 5'NTR specified the att phenotype of the three Sabin strains. Attenuating point mutations within the 5'NTR of the Sabin vaccine strains (nt 480, 481, and 472 in sero- types ... nucleotide sequences of wt PV strains with revertants of the att Sabin OPV strains were key in identifying the determinants of attenuation. But perhaps just as impor...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo sinh học: " Nucleocapsid formation and RNA synthesis of Marburg virus is dependent on two coiled coil motifs in the nucleoprotein" pot
... inter- action. We then investigated whether the integrity of the coiled coil region of NP is important for the binding of NP to the polymerase cofactor VP35, which connects the polymer- ase L to the NP-induced ... address the question of whether the interaction domain for VP35 is present in the coiled coil region itself or whether the coiled coil region is necess...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo sinh học: "Histone modification enhances the effectiveness of IL-13 receptor targeted immunotoxin in murine models of human pancreatic cancer" doc
... for the treatment of cutaneous T-cell lymphoma [26]. In the present study, we have examined the epigeneti c regulation of the IL-13Ra2 gene in pancreatic cancer cell lines and investigated whether ... with HDAC inhibitors in syngenic animal tumor models. Taken together, our results provide support for testing this novel combination in the clinic for the ther- apy of...
Ngày tải lên: 18/06/2014, 19:20
Báo cáo sinh học: " No relationship between the distribution of mast cells and the survival of stage IIIB colon cancer patients" pdf
... prognostic factor. Otherwise,themastcellcountintheinvasivemargin was associated with neither the clinicopathlogic para- meters nor overall survival, since the mast cell in the cancer stroma was ... conducted in accordance with the Helsinki Declaration and approved by the Ethic s Committee of our institution. Patients were informed of the investiga- tional nature of the...
Ngày tải lên: 18/06/2014, 19:20
Báo cáo sinh học: " Genetic lesions within the 3a gene of SARS-CoV" ppt
... expression of the 3a protein has been demonstrated during both in vitro and in vivo infection [5]. To determine if the mutation arises from repeated passages of the virus or if the mutation exists in the ... 3a gene of culture-derived SARS-CoV, which results in a protein with a distinctively shorter N- terminus than the wild-type form [6]. Protein 3a is one of t...
Ngày tải lên: 19/06/2014, 08:20