báo cáo sinh học:" The role of pharmacists in developing countries: the current scenario in Pakistan" potx
Báo cáo sinh học: "Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" pot
... for increas ing intensity and “ continuity” of stain- ing of the cell membrane[17]. For quantification of Her3 staining, we scored two compartmen ts of the cell - the cell membrane, using the ... extracellular ligand-binding domain, a transmembrane domain, and an intracytoplas mic tyrosine kinase domain[3-5]. Ligand binding to these receptors induces the formation of * Cor...
Ngày tải lên: 18/06/2014, 22:20
Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt
... or without hematoxylin staining. In hypoxia experiments, 3T3-L1 cells were maintained in a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati, OH, USA) constantly maintained at 1% O 2 . Culture medium ... lgÆmL )1 insulin, 1 lm dexamethasone, and 0.5 mm IDM). Cells were then maintained in DMEM con- taining 10% fetal bovine serum and 1 lgÆmL )1 insulin. The medium was replaced every...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Key role of the loop connecting the two beta strands of mussel defensin in its antimicrobial activity docx
... molecule comprising Ôresidues in the protruding domain consisting of the type VI b-turn and the first part of b-strand 3Õ (i.e. the b-hairpin loop and part of the adjoining b-sheet) and Ôresidues in the loop ... peptide K in which the sequence of the b-strands was maintained but the amino acids from loop 3 had been replaced by multiple Ser and Gly residues. Ther...
Ngày tải lên: 20/02/2014, 11:20
Tài liệu Báo cáo khoa học: Electrostatic role of aromatic ring stacking in the pH-sensitive modulation of a chymotrypsin-type serine protease, Achromobacter protease I pdf
... dependence of the pH-activity curve of API The pH-activity profiles depending on NaCl concentration were determined as part of the investigation into the shielding from solvent of the electrostatic interaction between ... position. In the struc- tural deviation, the solvent ASA of the side-chain of His210 increased with the decrease in size of the side-cha...
Ngày tải lên: 21/02/2014, 03:20
Báo cáo khoa học: Critical role of the plasma membrane for expression of mammalian mitochondrial side chain cleavage activity in yeast pptx
... mammalian cells [9], the SCC reaction is the rate-determining step in progesterone synthesis in yeast. The yeast SCC system offers the possibility of increasing or decreasing the availability of the endogenous ... hydrolysis, resulting in an increase in intracellular sterol trafficking. It is unclear, then, whether the corresponding increase in pregnenolone pro- duc...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: Essential role of the C-terminus in Melanocarpus albomyces laccase for enzyme production, catalytic properties and structure pdf
... preventing binding of oxygen. We analyzed the azide inhibition and determined the inhibition constants for sodium azide, in order to see the effect of the mutation (L559A) on the binding properties ... stability of the trinuclear site is decreased, the binding of azide to the trinuclear site may be decreased. The depletion of the T2 copper and chloride ion may...
Ngày tải lên: 16/03/2014, 00:20
Báo cáo khoa học: Dual role of Nbs1 in the ataxia telangiectasia mutateddependent DNA damage response ppt
... formation of MRN foci [19–21]. The Mre11-binding domain of human Nbs1 has been localized to amino acids 682–693 in the COOH- terminal region of the protein. Deletion of this region of Nbs1 results in ... damage, thereby promoting ATM-dependent signaling [23]. Domains similar to the ATM-binding domain of Nbs1 are also found in ATRIP and Ku80 and are required for the...
Ngày tải lên: 16/03/2014, 13:20
Báo cáo khoa học: Functional role of the linker region in purified human P-glycoprotein pot
... This kinetic analysis provided new insight into the role of the linker region. In addition, we fur- ther analyzed the functional role of the linker region based on the crystal structures of a ... exclude the effects of interacting proteins but can also be used to perform kinetic analy- ses of the native and linker-cleaved P-gp. In the present study, we invest...
Ngày tải lên: 29/03/2014, 23:20
Báo cáo khoa học: Functional role of Bb-chain N-terminal fragment in the fibrin polymerization process pdf
... situated in the E-domain of the fibrin molecule, the complementary site ‘c’ is suggested to be situated in the D-domain. We have tried to model the intermolecular binding between the D-domain of one ... situated in the bC-domain in a ‘knob’–‘hole’ type of interaction [7,9]. The remain- ing part of site ‘C’ (Bb19–46) probably remains bound to the fibrin D-domain...
Ngày tải lên: 30/03/2014, 03:20
báo cáo sinh học:" Alumni survey of Masters of Public Health (MPH) training at the Hanoi School of Public Health" pptx
... informs the policies of the Minis- try of Health in the broad area of public health. Among these tasks, training is considered to be the most impor- tant. In 1995, on direction of the Ministry of ... alumni interviewed were quite representative. Twelve of them were working in public/government sec- tor (including Ministry of Health offices, training institu- tion...
Ngày tải lên: 18/06/2014, 17:20