Báo cáo hóa học: "Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins" ppt

... 9:2 http://www.translational-medicine.com/content/9/1/2 Page 10 of 11 RESEA R C H Open Access Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins Tonia ... Buonomo et al.: Involvement of aryl hydrocarbon receptor signaling in the development of small cell lu...

Ngày tải lên: 18/06/2014, 16:20

... WYF. Silencing of ABCC2 by siRNA increased the sensitivity of cisplatin in CNE2 without changing the cellular viabilityFigure 3 Silencing of ABCC2 by siRNA increased the sensitivity of cisplatin in CNE2 ... analysis. In vitro the accumulation of intracellular cisplatin in these CNE2 cell clones with reduced expression of ABCC2 increased markedly, accompanied...

Ngày tải lên: 18/06/2014, 15:20

... 10 11 T cells infused. In the latter case, one is comparing 10 11 T cells transiently present by infusion versus 10 11 T cells stably present by engraftment. By moderate increments in risk, the ... essay. These concepts were originally presented at the 2 nd "Cellular Therapy of Cancer& quot; Symposium of the AT TACK (Adoptive engineered T -cell Targeting to...

Ngày tải lên: 18/06/2014, 16:20

... signals for the development, function and fitness of nTreg cells. Its signaling cascade is initiated by the binding of IL-2 to its trimeric IL-2 receptor (IL-2R) which consists of the a-chain (IL-2Ra; also ... that IL-2 signaling was required for the maintenance of the expression of the genes involved in the regulation of cell growth and metabolism [22]...

Ngày tải lên: 18/06/2014, 16:20

... euge- nin, indicating that eugenin is indeed acting through CCK 2 receptors. To further investigate the interaction of eugenin with CCK 2 receptors, we investigated the effect of eugenin on lymphocyte ... as stimulation of the proliferation of lymphocytes, activa- tion of CCK receptors stimulate production of inter- leukins and secretion of immunoglobulins on the mucosal...

Ngày tải lên: 19/02/2014, 16:20

... dual subcellular location, depending on the context. In the cytoplasm, hhLIM increases the stability of the actin cytoskeleton by promoting bundling of actin filaments [114]. In the nucleus, hhLIM interacts ... occurring C-terminal 100 kDa fragment of filamin, interacting with the motor protein dynein, may exert its inhibitory effect by interfering with inter- actions...

Ngày tải lên: 07/03/2014, 01:20

... does the moth OAT substitute for DAT in dopami- nergic signaling pathways in the moth CNS, and what is the nature of the mechanism that substitutes for OAT in the octopaminergic pathways in the ... TrnDAT in its lack of expression in the abdominal ganglia other than ganglion A1. It remains to be shown what system for OA uptake functions in the abdominal ner...

Ngày tải lên: 23/03/2014, 20:22

... lesser extent, in hepatoma cells, is clearly mitigated in the context of the entire upstream region, i.e. by the interposition of 1780 bp. We interpret the increase in activity of the upstream ... (muscle). The application of the ANOVA technique allowed us to segregate the main (intrinsic) activities of the respective elements from the effects of their...

Ngày tải lên: 23/03/2014, 20:22

... the processing of the HupL subunit [15]. It is plausible to assume that HynD is involved in the maturation of the HynL protein. Indeed, in the strain harboring the Tn5 transposon-inactivated ... HupK protein. Thirty one amino acid residues in the truncated HupK originated from the N-terminus, 37 aa from the C-terminus of the protein and 13 aa came from the mu...

Ngày tải lên: 31/03/2014, 01:20

... the term S in Table 3 (the sum of the lengths of all of the constraints) is proportional to c (the number of constraints), since there are no more than three pa- rameters in each constraint. ... what kinds of relations appear as constraints in the system, and on the order in which constraints are taken off the queue. The results for systems consist- in...

Ngày tải lên: 01/04/2014, 00:20