Báo cáo hóa học: " The emerging role of insulin-like growth factor 1 receptor (IGF1r) in gastrointestinal stromal tumors (GISTs)" pdf

... 8 :11 7 http://www.translational-medicine.com/content/8 /1/ 117 Page 2 of 6 COMM E N T ARY Open Access The emerging role of insulin-like growth factor 1 receptor (IGF1r) in gastrointestinal stromal tumors (GISTs) Maria A Pantaleo 1, 2* , Annalisa ... growing interest in insulin-like growth fa ctor 1 receptor (IGF1R) in medical oncology. IGF1R...

Ngày tải lên: 18/06/2014, 16:20

... 39.5 12 9 .1 45.4 11 6.8 42.2 CRP 0.80.4 0.90.4 ALT U/L # 72.7 25.6 49.2 17 .8 54.3 21. 8 Ferritin ng/mL 17 F 203.6 86.5 21 F 232.3 11 7.4 19 F 279.8 15 0.3 Ferritin ng/mL 19 M 396.4 15 3.5 24 M 3 81. 5 13 7.2 ... participated in the design of the study and in draft- ing the manuscript. GT conceived of the research, was the main investigator and the coordinator...

Ngày tải lên: 18/06/2014, 15:20

... (8.5%) 10 6 (10 0%) β 2 m 2 (1. 6%) 21 (16 .9%) 28 (22.6%) 73 (58.9%) 12 4 (10 0%) TAP1 0 (0.0%) 11 (8.9%) 39 ( 31. 5%) 74 (59.7%) 12 4 (10 0%) TAP2 16 (13 .1% ) 64 (52.5%) 27 (22 .1% ) 15 (12 .3%) 12 2 (10 0%) CD45 ... Beta2- microglobulin promotes the growth of human renal cell car- cinoma through the activation of the protein kinase A, cyclic AMP-responsive element-bind...

Ngày tải lên: 18/06/2014, 15:20

... A survey of 17 8 NF-Y binding CCAAT boxes. Nucleic Acids Res 26, 11 35 11 43. 12 Mantovani R (19 99) The molecular biology of the CCAAT-binding factor NF-Y. Gene 239, 15 –27. 13 van den Heuvel S & ... BubR1 is a protein important for spindle checkpoint activation. Expression of the BUB1B gene coding for BubR1 is undetectable in G 1 , but peaks in G 2 ⁄ M. Recently...

Ngày tải lên: 16/02/2014, 09:20

... representative verb of the impingement predicates class in German, the verb schlagen (hit) in examples (10 )- (12 ) above, we propose the semantic types in (17 ) and (18 ), which are in the spirit of the MRS-based ... results in trimming the dry branches off the bush. And this is what the semantic type in (16 ) captures. 3.3 Impingement Predicates In order...

Ngày tải lên: 17/03/2014, 22:20

... Secondly, in the variants Asn153fiAla and Asn153fiAsp the binding constants for cyanide to the ferric protein is about an order of magnitude lower than the corresponding binding constant of wild-type ... complex and the ferric protein) and the corres- ponding fit are shown in Fig. 4B. The observed rate of cyanide binding to the ferric enzyme linearly increased with the...

Ngày tải lên: 23/03/2014, 21:20

... 77 .17 3 IDO expression in primary tumors .598 .638 .878 1 .349 1. 818 .5 21 6.345 Bin1 expression in primary tumors 2 41 .378 .405 1 .525 .786 .375 1. 650 The density of IDO+cells in TDLN 1. 3 21 .524 ... existed in 9/ 71 cases (12 .7%), while the strong expression of Bin1 existed in 33/ 71 cases (46.5%). However, similar staining of IDO and Bin1 existed...

Ngày tải lên: 18/06/2014, 15:20

... .87 to . 91, with the cumulative percent of variation at 83%. Therefore the final scoring algorithm for the 12 items consisted of 1) the Global score (items 1 4 and 9– 11 ), 2) the Pain score (items ... to be 31. 1% and 32.3% respectively. Measurement Structure of the PPSM The exploratory factor analysis of items 1 11 suggested that the items loaded onto 2 fact...

Ngày tải lên: 18/06/2014, 18:20

... preliminary results indicating that the Dutch version of the KOOS question- naire contains one single factor, we retained in our analy- ses the original subscales of the Swedish version of the KOOS questionnaire. ... 0 .12 0.22 SF 0.36 0.42 0.33 0 .12 0.49 RF 0.28 0. 21 0.37 0.04 0.32 RE 0 .13 0 .18 0.28 -0.04 0.25 MH 0 .11 0 .12 0.36 -0.07 0 .18 VT 0.26 0.24 0.46 0 .10 0...

Ngày tải lên: 18/06/2014, 22:20

... for the planning, structuring and execution of the cross-cultural adaptation of the instrument [10 ]. The process was performed in five steps. In the first step, two translations from the original ... meaning of the terms in the pairs of statements (original and backtrans- lated versions) [9 ,11 ]. Visual Analogue Scales were used for the analysis of referent...

Ngày tải lên: 18/06/2014, 22:20