Báo cáo hóa học: " The status of clinical trials: Cause for concern" potx

... isolated one from another. The production of trialists is low. For example, over the period 1991-2002, of 232 PhD dissertations at the Bloomberg School of Public Health of the Johns Hop- kins ... address the issue would be for the NIH intramural program to initiate an integrated program that leads to the goal of buttressing the clinical trials infra- structure....

Ngày tải lên: 18/06/2014, 16:20

... mRNA, IL-6, mean of normal IL-6 level in plasma, and predictive cut-off level of IL-6 mRNA, respectively. (c) SPSS software analysis of the AUC of the ROC curve was 0.809 and 0.453 for IL-6 mRNA ... expres- sion (GE) in the serum and synchronizing GE changes with the clinical course of events. Processing of the blood and serum samples w as per- formed after blood sam...

Ngày tải lên: 18/06/2014, 16:20

... results, the RDQ may have the potential to meet some of the questionnaire needs for GERD clinical trials. In this study, the performance of the RDQ was assessed in a clinical treatment trial for patients ... Consistency of performance in two languages was also observed. The study population, being highly enriched for GERD, precluded determination of the predict...

Ngày tải lên: 18/06/2014, 22:20

... resection of hepat ic lesions. None of the patients had undergone either chemotherapy or radiotherapy before the collec- tion of the samples. The histopathologic characteristics of the colon ... review of the original pathology slides. The TNM c lassification system of the UICC (edition 6) was used for clinical staging, and the World H ealth Organi- zation cl...

Ngày tải lên: 18/06/2014, 16:20

... careful interpreta- tion of the results. For one, the rather low numbers and events in the prior phase I trial may not reflect the true, i.e. potentially low efficacy of BEXIDEM. Secondly, this phase ... ISRCTN35881130. Introduction TURB is the therapeutic gold standard for non-muscle invasive BC. Up to 50-70% of cases recur, rendering BC one of the most prevalent mal...

Ngày tải lên: 18/06/2014, 16:20

... measurement recorded before the death of one of the pairs of rabbits. The Shapiro-Wilk test was utilized to check the normality assumption before applying the pairwise t test on the mean of area of cicatrisation. Results Fibrinogen-thrombin ... just the pairs of rabbits in which neither the control nor the case rabbit died. In four pairs of rabbits, the contr...

Ngày tải lên: 18/06/2014, 16:20

... approved the final manuscript submitted to the journal. All authors were involved in the conception and design of the experiments. PG performed all experiments and prepared the draft of the manuscript. ... entirely the result of decreased GFR. To the best of our kno wledge, the effect of acyclovir on the renal tubular secretion of creatinine in vitro has not be...

Ngày tải lên: 18/06/2014, 16:20

... page of the demographic form that included diagnosis of psoriasis. The clinicians for these patients confirmed the diagnosis of psoriasis. N = total number of patients; n = number of patients for ... improves the symptoms of itch could therefore support a claim that the drug also improves HRQoL. The disease model reinforces the importance of measuring the co...

Ngày tải lên: 18/06/2014, 18:20

... Per- haps in persons with mild MS, the physical limitations of the disease are minimal and therefore irrespective of exer- cise status the impact of the disease on QoL in the physical domain is minimal. ... Non- exercisers. The MSIS-29 measures the impact of the dis- ease on the individual of the previous 2 weeks, it is possi- ble that regular exercise may impr...

Ngày tải lên: 18/06/2014, 19:20

... treat- ment effects. The purpose of this study was to evaluate the responsiveness of the UFS-QOL in a clinical study of treat- ment for uterine fibroids. Methods A post-hoc analysis of data from a ... health status changes and those who remain sta- ble? 3. What is the magnitude of the instrument's responsive- ness? A major strength of this study is the demon...

Ngày tải lên: 18/06/2014, 19:20