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evaluation of treatments deficiencies in the design of clinical trials

báo cáo khoa học:

báo cáo khoa học:" Cross-cultural validity of four quality of life scales in persons with spinal cord injury" docx

Báo cáo khoa học

... differ from the others could lay in the specific meaning of the items in the context of SCI and in the specific experiences of the affected persons While the other items may be related to the experienced ... solution in the post-hoc analyses appeared to be the merging of the response options “dissatisfying”, “rather dissatisfying” and “rather satisfying” This merging of the response options parallels the ... validity The current findings hint at potential cross-country bias in all four examined instruments largely in line with existing research In the case of the SWLS, two earlier studies using different...
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Báo cáo hóa học:

Báo cáo hóa học: " Quantifying the quality of hand movement in stroke patients through three-dimensional curvature" potx

Hóa học - Dầu khí

... D plots the log of the MSJ ratio against FMA-UE The dashed line shows the linear fitting of the data represented by the magenta circles and blue crosses Experiment 2: Distribution of the -log() ... acquisition of the data and recruitment of the patients YO, MK, and ML were involved in the interpretation of the results and critical revision of the manuscript All authors read and approved the final ... characteristics of the patients involved in the study Patient clinical characteristics are described in Table The average age of the patients in Experiment was 53.7 ± 15.0 years (range: 26 - 72 years) The...
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Báo cáo khoa học:

Báo cáo khoa học: "Effects of Corticosteroid and Electroacupuncture on Experimental Spinal Cord Injury in Dogs" doc

Báo cáo khoa học

... and pain [13] In this study, acupoints could be divided into local and distal points Local points were segmental urinary bladder points Local points on the governing vessel meridian in these ... regeneration of destroyed axons in the spinal cord The faster this regrowth took place, the more axons might gain access to their original distal axonal sheathes because there was less scar tissue at the ... Deahan Pharm Ltd Co., Korea) was administered during the surgical procedure Induction of spinal cord compression The skin incision was made at the dorsal midline from the 2nd to 5th lumbar vertebra...
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Báo cáo hóa học:

Báo cáo hóa học: " Technology-assisted training of arm-hand skills in stroke: concepts on reacquisition of motor control and therapist guidelines for rehabilitation technology design" ppt

Điện - Điện tử

... principle) [77] The training load for the patient is determined by the total time spent on therapeutic activity, the number of repetitions, the difficulty of the activity in terms of coordination, ... [19] TWrex aims to offer training of e.g following activities: shopping, washing the stove, cracking eggs, washing the arm, eating, making lemonade Limitations in movement of the shoulder (especially ... sensorimotor input during training of upper limb movement Nevertheless, the state -of- the- art robotic upper extremity training in stroke patients can play a very important role in alleviating therapists...
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báo cáo hóa học:

báo cáo hóa học:" Evaluation of deformity and hand function in cerebral palsy patients" pdf

Hóa học - Dầu khí

... function in the said population -0.519* 0.011 Informed consent for publication was obtained from patients or their guardians (in case of minors) during enrollment into the study Page of (page ... bear in mind though that the components of the MAULF could not be analyzed individually, hence it would reflect the patient's level of dysfunction but not the etiology of dysfunction Review of ... Sensory Assessment involved evaluation of static twopoint discrimination (2-pd) and stereognosis Static 2-pd was tested using the Baseline Aesthesiometer Stereognosis was assessed using the Stereognosis...
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Báo cáo y học:

Báo cáo y học: " Restoration of diaphragmatic function after diaphragm reinnervation by inferior laryngeal nerve; experimental study in rabbits" pot

Báo cáo khoa học

... performed during a bilateral supramaximal stimulation of the phrenic nerve; % shortening, percentage of shortening in relation to the resting length of the muscular fiber measured at the end of the expiration ... the time of evaluation In two animals, this residual innervation was due to a branch originating from the sixth cervical root discovered after cervical dissection However, the origin of the innervation ... branch of ILN and r.C4 was anastomosed to the nerve of the sternothyroid muscle The nerve of the sternothyroid muscle issues from the descending branch of the hypoglossal nerve, innervates the sternothyroid...
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Robot assisted rehabilitation of forearm and hand function after stroke

Robot assisted rehabilitation of forearm and hand function after stroke

Cao đẳng - Đại học

... vmax zin number of joints in the system [unitless] endpoint of the parallelogram system (finger fixation) [cm] total number of trials in a set [unitless] motor for the linear opening of the Haptic ... motor for the rotation of the Haptic Knob [unitless] normalized number of zero crossing of the acceleration [1/s] number of crossing in and out of target window [unitless] number of crossing in and ... A robot maintaining the patient and guiding the movement of the legs can reduce walking rehabilitation to a monitoring and analysis task for the therapists with the possibility of increased exercise...
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Báo cáo Y học: The expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione function in spermatogenesis doc

Báo cáo Y học: The expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione function in spermatogenesis doc

Báo cáo khoa học

... protein and the mRNA were faint Effects of inhibitors of cGCS and GR on primary cultured testicular cells To investigate the contribution of de novo synthesis and the recycling of GSH to the intracellular ... protein metabolism in these cells Histone is rich in the basic amino acids, lysine and arginine, but contains no cysteine Protamine, which is replaced for hitstone via transit proteins during ... level of GR in the epithelia of the epididymis (Fig 1) As the epididymis is rich in sulfoxidase, the oxidation of sulfhydryls in the sperm head and tail would be mediated by this enzyme in a specific...
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late neoclassical economics restoration of theoretical humanism in contemporary mainstream economics

late neoclassical economics restoration of theoretical humanism in contemporary mainstream economics

Kinh tế

... began to represent the loss of the disciplinary hegemony of the former as the “death” of the latter Without doubt, the loss of the disciplinary hegemony of the general equilibrium theory is a significant ... pushed to the margins of the discipline In this sense, notwithstanding the trope of the “pluralist turn” in the mainstream economics and its supposed “break” from the neoclassical orthodoxy, the discipline ... to the model of perfect competition as their ultimate point of reference: In the case of the laissez faire camp, the model of perfect competition (whether it is enframed in the Walrasian or the...
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Báo cáo hóa học:

Báo cáo hóa học: " Quantification of the effects of an alpha-2 adrenergic agonist on reflex properties in spinal cord injury using a system identification technique" pptx

Hóa học - Dầu khí

... relating position and torque The IRF characterizes the behavior of the system over its entire range of frequencies The intrinsic IRF was convolved with the experimental input to predict the intrinsic ... line) in each panel indicates what would be expected if there were no change due to the medication Points below the line indicate decreases following the administration of tizanidine, while points ... predictor of clinical/ therapeutic efficacy, in that clear reductions in reflex torque for a small dose may signify the likelihood of strong therapeutic effects of the drug Competing interests The authors...
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Báo cáo hóa học:

Báo cáo hóa học: " Kinematic analysis of the daily activity of drinking from a glass in a population with cervical spinal cord injury" potx

Hóa học - Dầu khí

... was the onset of displacement of the marker on the head of the third metacarpal and the end of the cycle was the return of the marker to the starting point after completing the drinking task As ... Test-retest involved recording the action of the drinking task and then removing the markers The entire procedure was repeated from the beginning fifteen minutes later Data processing The recordings ... reaching out for the glass from the starting position and grasping it, raising the glass to the mouth, drinking, lowering the glass to the pickup point, and returning the hand to the starting...
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báo cáo hóa học:

báo cáo hóa học: " The effects of powered ankle-foot orthoses on joint kinematics and muscle activation during walking in individuals with incomplete spinal cord injury" pptx

Hóa học - Dầu khí

... walking The ankle plantar flexors provide ~70% of the joint work during walking, far more than the muscles crossing the hip or knee [22,23] The muscles acting at the ankle joint act to support the ... plasticity in spinal stepping and standing Advances in Neurology 1997, 72:233-247 Lovely RG, Gregor RJ, Roy RR, Edgerton VR: Effects of training on the recovery of full-weight-bearing stepping in the ... cycle Finally, to examine differences in the timing of assistance between the therapist-controlled and patient-controlled conditions, we calculated the onset of the control signal and the onset of...
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Báo cáo lâm nghiệp:

Báo cáo lâm nghiệp: "Effects of soil mechanical treatments combined with bramble and bracken control on the restoration of degraded understory in an ancient beech forest" pptx

Báo cáo khoa học

... which is the machine used for the majority of soil tillage operations carried out in the past in the Sonian Forest, and a disc plough, a machine of which the use is Soil mechanical treatments in a ... sylvatica) are the main species [30] Since the plantation work of the Austrian administration at the end of the 18th century, it is now composed of 74% beech (Fagus sylvatica) with only a few other woody ... gradually be smoothed by raindrop energy [29] Most of the studies dealing with the in uence of tillage on the physical state of the soil have been carried out immediately after soil loosening To our...
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Báo cáo khoa học:

Báo cáo khoa học: "Transplantation of canine umbilical cord blood-derived mesenchymal stem cells in experimentally induced spinal cord injured dogs" pot

Báo cáo khoa học

... ytisrevinU lanoitaN luoeS fo ’slaminA yrotarobaL fo esU dna eraC eht rof ediuG‘ eht fo senilediug eht ot gnidrocca demrofrep saw noitagitsevni sihT yduts yrujni droc lanips latnemirepxe eht rof desu ... erew sgod ehT ICS eht retfa keew a demrofrep saw sCSM-BCU eninac fo noitatnalpsnarT :FSCGhmr fo noitcejni dna sCSM-BCU eninac fo noitatnalpsnarT noitcejni eht rof noitulos enilas fo lµ 051 ni 601 ... ilumits cinegotim cificepsnon ro ralullec yb decudni noitarefilorp etycohpmyl-T sserppus sllec lamorts worram enob namuH MA innaiG ,S itnasirG ,P iccuettaM ,DP inognoL ,M isenaliM ,M ingaM ,C...
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Báo cáo khoa học:

Báo cáo khoa học: "Functional recovery and neural differentiation after transplantation of allogenic adipose-derived stem cells in a canine model of acute spinal cord injury" potx

Báo cáo khoa học

... droplets (Fig 1B) The colonies of ASCs were subjected to Alizarin red S staining weeks after the initiation of osteogenic differentiation Intense Alizarin red S staining of the colonies confirmed ... For group V, the injured site was exposed by dorsal laminectomy and 150 μL of PBS was injected into the spinal cord at locations to depths of mm using a 30 gauge needle (middle of the injury site, ... movement and with deep pain sensation The Olby score for the ASC group increased in the weeks after injury and was 4.6 at the end of the study, with moveable joints of the pelvic limbs This score...
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Báo cáo khoa học:

Báo cáo khoa học: "Relationship of cognitive function in patients with schizophrenia in remission to disability: a cross-sectional study in an Indian sample" pps

Báo cáo khoa học

... analysis and interpretation of results PBM was involved in review of the manuscript including extensive revision of interpretation and discussion of the results AN and RRP reviewed the methodology, ... than the controls but the number of years of education was slightly higher in the control group The mean duration of illness was 11.3 ± 5.8 years, ranging from to 20 years A total of 24% of the ... remained employed in spite of the significant cognitive deficits Similar employment rates have been shown in previous studies from India [14] The findings in the present study emphasize the importance...
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Báo cáo y học:

Báo cáo y học: "Vitamin D receptor gene polymorphisms and susceptibility of hand osteoarthritis in Finnish wome" pdf

Báo cáo khoa học

... of the involvement of the VDR polymorphism in the etiology of symmetrical hand OA In addition, our findings suggest a detrimental effect of low dietary calcium intake on OA The findings remain ... with the AATT genotype the highest odds of hand osteophytes as compared with the AAtt genotype The direction of these associations contrast the findings in the studies of osteophytes formation in ... was defined as a subcategory of OA in at least two symmetrical pairs of the joints (if two joints of the hand are affected, the same joints of the opposite hand are also affected) If the subject...
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Báo cáo y học:

Báo cáo y học: " Interrelated modulation of endothelial function in Behcet''''s disease by clinical activity and corticosteroid treatmen" ppt

Báo cáo khoa học

... PK participated in designing the study and helped to revise the manuscript MM participated in designing the study and helped to revise the manuscript JL participated in designing the study and ... together with the presence of the significant interaction between BD activity and corticosteroid treatment, the results obtained in the cross-sectional part of the study suggest that in the presence ... [3-5], may restore endothelial dysfunction by counteracting the harmful effects of relapsing inflammation Competing interests The authors declare that they have no competing interests Authors' contributions...
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Báo cáo y học:

Báo cáo y học: "Standards of evidence in chronobiology: critical review of a report that restoration of Bmal1 expression in the dorsomedial hypothalamus is sufficient to restore circadian food anticipatory rhythms in Bmal1-/- mice" pot

Báo cáo khoa học

... either side of the blue line Therefore, in the actogram-style plots of the same data, the dark sections (indicating higher temperature) should also be symmetrical on either side of the blue line ... restricted feeding restores the rhythms of expression of the clock protein, Period2, in the oval nucleus of the bed nucleus of the stria terminalis and central nucleus of the amygdala in adrenalectomized ... to ZT7 The amplitude of the rhythm only appears low in those figures due to the scaling of the y-axis During restricted feeding, the phase of the rhythm was shifted and its amplitude increased...
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